Viser treff 19121-19140 av 36331

    • The 3‐D Distribution of Artificial Aurora Induced by HF Radio Waves in the Ionosphere 

      Kvammen, Andreas; Gustavsson, Björn Johan; Sergienko, Tima; Brändström, Urban; Rietveld, Michael T; Rexer, Theresa; Vierinen, Juha (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-21)
      We present 3‐D excitation rate estimates of artificial aurora in the ionospheric F layer, induced by high‐frequency radio waves from the European Incoherent Scatter heating facility. Simultaneous imaging of the artificial aurora was done with four separate Auroral Large Imaging System stations, permitting tomography‐like 3‐D auroral reconstruction of the enhanced atomic oxygen emissions at 6,300, ...
    • Addition of marine omega-3 fatty acids to statins in familial hypercholesterolemia does not affect in vivo or in vitro endothelial function 

      Hande, Liv Nesse; Thunhaug, Hilde; Enebakk, Terje; Ludviksen, Judith K; Pettersen, Kristin; Hovland, Anders; Lappegård, Knut Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-29)
      <i>Background</i> - Prestatin trials reported positive effects of omega-3 polyunsaturated fatty acids (n-3 PUFA) in cardiovascular disease, whereas recent studies and meta-analyses have not reproduced these results. The effect of n-3 PUFA in patients with familial hypercholesterolemia (FH), a group with particularly high risk of cardiovascular disease, is not well established.<p><p> <i>Objective</i> ...
    • Hoffmann´s syndrome necessitating forearm fasciotomy: a case report 

      Aarsæther, Erling Johan; Joakimsen, Ragnar Martin; Halvorsen, Hanne; Sildnes, Trude; Sivertsen, Olav; Due, Jan (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-02)
      <i>Background</i> - Hoffmann’s syndrome is a rare form of hypothyroid myopathy. Only a few cases of fasciotomy in this setting have previously been reported.<p><p> <i>Case presentation</i> - A 41-year-old Caucasian man under treatment for hypothyroidism presented with acute-onset severe pain in his forearm for no obvious reason and was admitted to our emergency room. He eventually developed ...
    • Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma 

      Pölonen, Petri; Jawahar Deen, Ashik; Leinonen, Hanna M.; Jyrkkänen, Henna-Kaisa; Kuosmanen, Suvi; Mononen, Mimmi; Jain, Ashish; Tuomainen, Tomi; Pasonen-Seppänen, Sanna; Hartikainen, Jaana M.; Mannermaa, Arto; Nykter, Matti; Tavi, Pasi; Johansen, Terje; Heinäniemi, Merja; Levonen, Anna-Liisa (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-23)
      Accumulating evidence suggests that constitutively active Nrf2 has a pivotal role in cancer as it induces pro-survival genes that promote cancer cell proliferation and chemoresistance. The mechanisms of Nrf2 dysregulation and functions in cancer have not been fully characterized. Here, we jointly analyzed the Broad-Novartis Cancer Cell Line Encyclopedia (CCLE) and the Cancer Genome Atlas (TCGA) ...
    • The Case for Combining a Large Low‐Band Very High Frequency Transmitter With Multiple Receiving Arrays for Geospace Research: A Geospace Radar 

      Hysell, David; Chau, Jorge Luis; Coles, William A; Milla, Marco; Obenberger, Kenneth; Vierinen, Juha (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-09)
      We argue that combining a high‐power, large‐aperture radar transmitter with several large‐aperture receiving arrays to make a geospace radar—a radar capable of probing near‐Earth space from the upper troposphere through to the solar corona—would transform geospace research. We review the emergence of incoherent scatter radar in the 1960s as an agent that unified early, pioneering research in geospace ...
    • Genetic population structure and variation at phenology‐related loci in anadromous Arctic char (Salvelinus alpinus) 

      Madsen, Rikke; Jacobsen, Magnus W; O´Malley, Kathleen G; Nygaard, Rasmus; Præbel, Kim; Jonsson, Bjarni; Pujolar, Jose M; Fraser, Dylan J; Bernatchez, Louis; Hansen, Michael M (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-03)
      The Arctic will be especially affected by climate change, resulting in altered seasonal timing. Anadromous Arctic char (<i>Salvelinus alpinus</i>) is strongly influenced by sea surface temperature (SST) delimiting time periods available for foraging in the sea. Recent studies of salmonid species have shown variation at phenology‐related loci associated with timing of migration and spawning. We ...
    • TAK1 converts Sequestosome 1/p62 from an autophagy receptor to a signaling platform 

      Kehl, Stephanie R; Soos, Brandy-Lee A; Saha, Bhaskar; Choi, Seong Won; Herren, Anthony W; Johansen, Terje; Mandell, Michael A (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-25)
      The protein p62/Sequestosome 1 (p62) has been described as a selective autophagy receptor and independently as a platform for pro‐inflammatory and other intracellular signaling. How these seemingly disparate functional roles of p62 are coordinated has not been resolved. Here, we show that TAK1, a kinase involved in immune signaling, negatively regulates p62 action in autophagy. TAK1 reduces p62 ...
    • A raster version of the Circumpolar Arctic Vegetation Map (CAVM) 

      Raynolds, Martha K.; Walker, Donald A.; Balser, Andrew; Bay, Christian; Campbell, Mitch; Cherosov, Mikhail M.; Daniëls, Fred J.A.; Eidesen, Pernille Bronken; Ermokhina, Ksenia A.; Frost, Gerald V.; Jedrzejek, Birgit; Jorgenson, M. Torre; Kennedy, Blair E.; Kholod, Sergei S.; Lavrinenko, Igor A.; Lavrinenko, Olga V.; Magnússon, Borgþór; Matveyeva, Nadezhda V.; Metúsalemsson, Sigmar; Nilsen, Lennart; Olthof, Ian; Pospelov, Igor N.; Pospelova, Elena B.; Pouliot, Darren; Razzhivin, Vladimir; Schaepman-Strub, Gabriela; Šibík, Jozef; Telyatnikov, Mikhail Yu.; Troeva, Elena (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-17)
      Land cover maps are the basic data layer required for understanding and modeling ecological patterns and processes. The Circumpolar Arctic Vegetation Map (CAVM), produced in 2003, has been widely used as a base map for studies in the arctic tundra biome. However, the relatively coarse resolution and vector format of the map were not compatible with many other data sets. We present a new version of ...
    • Intrauterine progestin therapy as a new approach to premalignant endometrial polyps: A prospective observational study 

      Sletten, Elise Thoresen; Arnes, Marit; Vereide, Anne Beate; Ørbo, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09)
      Background/Aim: Endometrial hyperplastic polyps (EHP) may progress to endometrial carcinoma (EC) if left untreated. We aimed to prospectively investigate the efficacy of the low-dose levonorgestrel intrauterine system (LNG-IUS) as therapy for EHP with malignant potential. Patients and Methods: In total, 37 women with EHP underwent therapy with LNG-IUS containing 13.5 mg levonorgestrel for six months ...
    • Selective Autophagy: RNA Comes from the Vault to Regulate p62/SQSTM1 

      Johansen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-22)
      A new study shows that the oligomerization of p62/Sequestosome-1 (SQSTM1) — a selective autophagy receptor and signaling adapter — is regulated directly by vault RNA. This riboregulation negatively affects the aggregation state of p62 and thereby its autophagic degradation and its role as a selective autophagy receptor.
    • Breast cancer risk after recent childbirth: A pooled analysis of 15 prospective studies 

      Nichols, Hazel B.; Schoemaker, Minouk J.; Cai, Jianwen; Xu, Jiawei; Wright, Lauren B.; Brook, Mark N.; Jones, Michael E.; Adami, Hans Olov; Baglietto, Laura; Bertrand, Kimberly A.; Blot, William J.; Boutron-Ruault, Marie-Christine; Dorronsoro, Miren; Dossus, Laure; Eliassen, A. Heather; Giles, Graham G.; Gram, Inger Torhild; Hankinson, Susan E.; Hoffman-Bolton, Judy; Kaaks, Rudolf; Key, Timothy J.; Kitahara, Cari M.; Larsson, Susanna C.; Linet, Martha; Merritt, Melissa A.; Milne, Roger L.; Pala, Valeria; Palmer, Julie R.; Peeters, Petra H.; Riboli, Elio; Sund, Malin; Tamimi, Rulla M.; Tjønneland, Anne; Trichopoulou, Antonia; Ursin, Giske; Vatten, Lars Johan; Visvanathan, Kala; Weiderpass, Elisabete; Wolk, Alicja; Zheng, Wei; Weinberg, Clarice R.; Swerdlow, Anthony J.; Sandler, Dale P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-01)
      <i>Background</i>: Parity is widely recognized as protective for breast cancer, but breast cancer risk may be increased shortly after childbirth. Whether this risk varies with breastfeeding, family history of breast cancer, or specific tumor subtype has rarely been evaluated.<p> <p><i>Objective</i>: To characterize breast cancer risk in relation to recent childbirth.<p> <p>Design</i> : Pooled ...
    • Minnesøkologi og den uregjerlige industriarven 

      Bangstad, Torgeir Rinke (Journal article; Tidsskriftartikkel; Peer reviewed, 2019)
      This essay explores the entangled material and biological afterlife of coal and steel industries in the German Ruhr region. The industrial nature, <i>Industrienatur</i>, of the heritage site <i>Kokerei Hansa</i> in Dortmund serves as starting point for a broader reflection on both the nature of memory and the memory of nature. Drawing on new materialist theory and media ecology, the ambition of this ...
    • Aliivibrio wodanis as a production host: development of genetic tools for expression of cold-active enzymes 

      Johansson Söderberg, Jenny; Grgic, Miriam; Hjerde, Erik; Haugen, Peik (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-11)
      <i>Background</i>: Heterologous production of cold-adapted proteins currently represents one of the greatest bottlenecks in the ongoing bioprospecting eforts to fnd new enzymes from low-temperature environments, such as, the polar oceans that represent essentially untapped resources in this respect. In mesophilic expression hosts such as <i>Escherichia coli</i>, cold-adapted enzymes often form ...
    • Small places, universal stories. Diversity, film policy and the geographical dimension of filmmaking 

      Sand, Stine Agnete (Journal article; Tidsskriftartikkel; Peer reviewed, 2019)
      This article examines approaches to cultural diversity in a global- local axis. Can one talk about local cultural diversity in a film industry that is increasingly global? Cultural diversity is a goal in European film policy and an important rationale behind the support of European films. Geographical location is a key factor when discussing filmmaking because of the assumption that film and television ...
    • Måleegenskaper ved den norske versjonen av Wechsler Intelligence Scale for Children – Fifth Edition (WISC-V) 

      Brøndbo, Per Håkan; Egeland, Jens (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-16)
      Wechsler Intelligence Scale for Children – Fifth Edition (WISC-V) ble publisert i USA i 2014 og den norske versjonen kom i 2017. Norsk og internasjonal rettighetshaver er Pearson Assessment. Oversettelsesarbeidet, inkludert kulturell tilpasning, ble gjennomført av Pearson Assessment med hjelp fra klinisk ekspertise i Norge, Danmark og Sverige. WISC-V er en individuelt administrert test av intellektuelle ...
    • Activated dendritic cells and monocytes in HIV immunological nonresponders: HIV-induced interferon-inducible protein-10 correlates with low future CD4+ recovery 

      Stiksrud, Birgitte; Aass, Hans Christian Dalsbotten; Lorvik, Kristina Berg; Ueland, Thor; Trøseid, Marius; Dyrhol-Riise, Anne Ma (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-01)
      <i>Objective</i>: To explore monocyte and dendritic cell immune responses, and their association with future CD4<sup>+</sup> gain in treated HIV patients with suboptimal CD4<sup>+</sup> recovery.<p> <p><i>Design</i>: A cross-sectional study of HIV-infected, virally suppressed individuals on antiretroviral therapy for at least 24 months; 41 immunological nonresponders (INRs) (CD4+ cell count <400 ...
    • A transdisciplinary approach to Brucella in Muskoxen of the Western Canadian Arctic 1989-2016 

      Tomaselli, Matilde; Elkin, Brett T.; Kutz, Susan; Harms, Naomi Jane; Nymo, Ingebjørg Helena; Davison, Tracy; Leclerc, Lise-Marie; Branigan, Marsha; Dumond, Mathieu; Tryland, Morten; Checkley, Sylvia L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-14)
      Brucella serostatus was evaluated in 3189 muskoxen sampled between 1989 and 2016 from various locations of the Canadian Arctic archipelago and mainland, near the communities of Sachs Harbour and Ulukhaktok, Northwest Territories, and Cambridge Bay and Kugluktuk, Nunavut. Brucella antibodies were found only in muskoxen sampled around Cambridge Bay, both on southern Victoria Island and on the adjacent ...
    • Association of socioeconomic status with consumption of cigarettes, illicit drugs, and alcohol 

      Marzban, Maryam; Hadji, Maryam; Gholipour, Mahin; Rashidian, Hamideh; Rezaianzadeh, Abbas; Hasanzadeh, Jafar; Haghdoost, Ali Akbar; Rahimi-Movaghar, Afarin; Ghiasvand, Reza; Moradi, Abdolvahab; Khavari-Daneshvar, Hossein; Weiderpass, Elisabete; Kamangar, Farin; Zendehdel, Kazem (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-18)
      <i>Introduction and Aims</i>: Socioeconomic Status (SES) is considered as one of the important factors associated with use of various drugs. The present study aimed to investigate the effect of SES on cigarette smoking, alcohol use, drug use, and passive exposure to opium and cigarette smoke.<p> <p><i>Design and Methods</i>: In this study, which is part of a ...
    • Framtida til Historisk tidsskrift 

      Fulsås, Narve (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-04)
      Framtida til Historisk tidsskrift var tema ved avslutninga av Norske historiedagar i Tønsberg i år. Som hovudredaktør av tidsskriftet 2015–2018 var eg invitert til å innleie. Innlegget her er basert på innleiinga, men også utvida som respons på synspunkt som kom fram i den påfølgjande panel- og plenumsdebatten.
    • Validation of prediction models of severe disease course and non-achievement of remission in juvenile idiopathic arthritis: part 1—results of the Canadian model in the Nordic cohort 

      Rypdal, Veronika Gjertsen; Guzman, Jaime; Henrey, A; Loughin, T; Glerup, Mia; Arnstad, Ellen Dalen; Aalto, Kristiina; Rygg, Marite; Nielsen, Susan M.; Herlin, Troels; Fasth, Anders; Berntson, Lillemor; Rypdal, Martin Wibe; Nordal, Ellen Berit (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-05)
      <i>Background</i> - Models to predict disease course and long-term outcome based on clinical characteristics at disease onset may guide early treatment strategies in juvenile idiopathic arthritis (JIA). Before a prediction model can be recommended for use in clinical practice, it needs to be validated in a different cohort than the one used for building the model. The aim of the current study was ...