Blar i tittel Det helsevitenskapelige fakultet

Viser treff 6084-6103 av 10152

    • Miljøgifter og svangerskapsutfall i Vietnam 

      Gansmo, Marit; Johansen, Silje Udjus (Master thesis; Mastergradsoppgave, 2005-09)

    • Miljørisikovurdering genmodifisert mais MON 89034 x NK603 fra Monsanto Company (EFSA/GMO/NL/2009/72). Uttalelse fra Faggruppe for genmodifiserte organismer Vitenskapskomiteen for mattrygghet 

      Sorteberg, Hilde-Gunn Opsahl; Bøhn, Thomas; Finne, Merethe Aasmo; Holck, Askild Lorentz; Klungland, Helge; Meadow, Richard; Myhr, Anne Ingeborg; Nerland, Audun Helge; Nes, Ingolf; Nielsen, Kaare Magne; Stabbetorp, Odd Egil; Vikse, Rose (Research report; Forskningsrapport, 2010-04-07)
      Helse- og miljørisikovurderingen av den insektresistente og herbicidtolerante maishybriden MON 89034 x NK603 (EFSA/GMO/NL/2009/72) fra Monsanto Company er utført av Faggruppe for genmodifiserte organismer i Vitenskapskomiteen for mattrygghet (VKM). VKM er bedt av Direktoratet for naturforvalting (DN) om å vurdere miljørisiko ved en eventuell godkjenning av maislinje MON 89034 x NK603 til dyrking og ...

    • Milk and risk of colorectal, colon and rectal cancer in the Norwegian Women and Cancer (NOWAC) Cohort Study 

      Bakken, Toril; Braaten, Tonje; Olsen, Anja; Hjartåker, Anette; Lund, Eiliv; Skeie, Guri (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-17)
      According to World Cancer Research Fund International/American Institute for Cancer Research, it is ‘probable’ that dairy products decrease the risk of colorectal cancer (CRC). However, meta-analyses restricted to women have not shown associations between milk intake and risk of CRC. The aim of this study was to examine the association between milk intake and risk of CRC, colon cancer and rectal ...

    • Mimicking regional and fasted/fed state conditions in the intestine with the mucus-PVPA in vitro model: The impact of pH and simulated intestinal fluids on drug permeability 

      Falavigna, Margherita; Klitgaard, Mette; Steene, Erik; Flaten, Gøril Eide (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-27)
      Intestinal drug absorption following oral administration can be influenced by regional conditions (absorbing surface area, bacterial flora, motility, pH, mucus thickness) and food intake, all of which affect drug solubility and permeability. Therefore, it is crucial to assess the impact of these conditions on the drugability of drugs and formulations. In this study, the ability of the liposome-based ...

    • Mind the Gap! Lay and Medical Perceptions of Risks Associated with the Use of Alternative Treatment and Conventional Medicine 

      Salamonsen, Anita (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-19)
      Studies of the widespread use of complementary and alternative medicine (CAM) demonstrate that CAM users relate to both subjective, experience-based knowledge and medical knowledge in treatment decisions. The aim of this study was to explore lay and medical risk perceptions associated with CAM and conventional medicine.<br> <b>Patients and Methods</b> Twenty-five Norwegian users of CAM who ...

    • Mind-wandering: mechanistic insights from lesion, tDCS, and iEEG 

      Kam, Julia W.Y.; Mittner, Matthias; Knight, Robert T (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-24)
      Cognitive neuroscience has witnessed a surge of interest in investigating the neural correlates of the mind when it drifts away from an ongoing task and the external environment. To that end, functional neuroimaging research has consistently implicated the default mode network (DMN) and frontoparietal control network (FPCN) in mind-wandering. Yet, it remains unknown which subregions within these ...

    • Mindfulness Mediates the Effect of a Psychological Online Intervention for Psychosis on Self-Reported Hallucinations: A Secondary Analysis of Voice Hearers From the EviBaS Trial 

      Lüdtke, Thies; Platow-Kohlschein, Heike; Rüegg, Nina; Berger, Thomas; Moritz, Steffen; Westermann, Stefan (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-03)
      <i>Background</i>: Psychological online interventions (POIs) could represent a promising approach to narrow the treatment gap in psychosis but it remains unclear whether improving mindfulness functions as a mechanism of change in POIs. For the present study, we examined if mindfulness mediates the effect of a comprehensive POI on distressing (auditory) hallucinations.<p> <p><i>Methods</i>: We ...

    • Mindfulness training for chronic fatigue syndrome: a pilot study 

      Sollie, Katinka; Næss, Eva Therese; Solhaug, Ida; Thimm, Jens (Journal article; Tidsskriftartikkel; Peer reviewed, 2017)
      Background: <br> Chronic fatigue syndrome (CFS) is a condition characterized by persistent and unexplained fatigue that may result in severe impairment of daily functioning. Currently, there is no curative treatment for CFS, and many patients experience the existing interventions as ineffective. Thus, there is a need for new approaches that target psychological maintenance factors and coping. ...

    • Mindfulness training for stress management: a randomised controlled study of medical and psychology students 

      de Vibe, Michael; Solhaug, Ida; Tyssen, Reidar; Friborg, Oddgeir; Rosenvinge, Jan H; Sørlie, Tore; Bjørndal, Arild (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Distress and burnout among medical and psychology professionals are commonly reported and have implications for the quality of patient care delivered. Already in the course of university studies, medicine and psychology students report mental distress and low life satisfaction. There is a need for interventions that promote better coping skills in students in order to prevent distress ...

    • Mindfulness-Based Stress Reduction for Integrative Cancer Care : a Summary of Evidence 

      Musial, Frauke; Büssing, Arndt; Heusser, Peter; Choi, Kyung-Eun; Ostermann, Thomas (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      This paper provides a comprehensive overview of the relevant existing evidence, and critically appraises the use of mindfulness-based stress reduction (MBSR) in cancer care. Furthermore, a meta-analysis was conducted in order to investigate the effect of MBSR on quality of life (QoL), mood, and distress. Besides 6 reviews (5 systematic, 1 meta-analytic) which are reported separately, a total of 19 ...

    • Mindfulnessbasert mestring for personer diagnostisert med ME/CFS - En pilotstudie 

      Sollie, Katinka (Master thesis; Mastergradsoppgave, 2014-05-02)
      Kronisk utmattelsessyndrom (ME/CFS) er en tilstand karakterisert av vedvarende og uforklarlig utmattelse som resulterer i alvorlig funksjonsnedsettelse. Det finnes ingen kurativ behandling for ME/CFS, og eksisterende intervensjoner oppleves av mange med ME/CFS som ineffektive. Det derfor er behov for å finne en alternativ tilnærming. Det antas å være hensiktsmessig å fokusere på en mestringsbasert ...

    • "Mine naturopplevelser". En fenomenologisk studie av fire personers naturopplevelser etter å ha gått turen Norge på langs 

      Marø, Erlend (Master thesis; Mastergradsoppgave, 2017-05-15)
      Denne undersøkelsen gir et dypdykk i fire utvalgte personers livsverdensbeskrivelser av naturopplevelse etter at de gikk turen Norge på langs i løpet av 2014-2016. Problemstillingen lød slik: Hvordan beskriver fire utvalgte personer som har gått Norge på langs de siste tre årene sine naturopplevelser etter denne turen? Naturopplevelse ble delt inn i opplevelser med naturen, opplevelser med det sosiale ...

    • Minimal important change was on the lower spectrum of previous estimates and responsiveness was sufficient for core outcomes in chronic low back pain 

      Bråten, Lars Christian Haugli; Grøvle, Lars; Wigemyr, Monica; Wilhelmsen, Maja; Gjefsen, Elisabeth; Espeland, Ansgar; Haugen, Anne Julsrud; Skouen, Jan Sture; Brox, Jens Ivar; Zwart, John Anker Henrik; Storheim, Kjersti; Ostelo, Raymond WJG.; Grotle, Margreth (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-01)
      Objectives: The objective of this study was to estimate the minimal important change (MIC) and responsiveness of core patient reported outcome measures for chronic low back pain (LBP) and Modic changes.<p> <p>Study Design and Setting: In the Antibiotics in Modic changes (AIM) trial we measured disability (RMDQ, ODI), LBP intensity (NRS) and health-related quality of life (EQ5D) electronically at ...

    • Minimum effective volume of ropivacaine 7.5mg/ml for an ultrasound-guided infraclavicular brachial plexus block 

      Flohr-Madsen, Sandra; Ytrebø, Lars Marius; Kregnes, Sylvia Beate; Wilsgaard, Tom; Klaastad, Øivind (Journal article; Tidsskriftartikkel; Peer reviewed, 2013-02-18)
      <p><i>Background - </i>Ultrasound guidance has been shown to reduce the minimum effective volume (MEV) of local anaesthetics for several peripheral nerve blocks. Although the lateral sagittal infraclavicular block (LSIB) is a well‐established anaesthesia method, MEV for this technique has not been established. Our aim with this study was to determine the MEV using ropivacaine 7.5 mg/ml for the LSIB ...

    • Minor changes in the incidence of primary and secondary involuntary childlessness across birth cohorts 1916 to 1975, but major differences in treatment success 

      Skjeldestad, Finn Egil (Journal article; Tidsskriftartikkel, 2023-07-12)
      There have been tremendous advances in assisted reproductive technologies (ARTs) over the past 50 years. The present study assessed infertility outcomes among women of reproductive age during this period. The seventh survey of the Tromsø Study (Tromsø7, 2015–16) recruited Tromsø residents aged 40–98 years. The questionnaire collected information on sociodemographics and infertility, as well as data ...

    • Minor oral soft tissue surgery for the general dental practitioner 

      Lein, Ingvild Årøen (Master thesis; Mastergradsoppgave, 2011-06)
      In this study, a guide for soft tissue surgery has been made, based on a review. The guide should serve as an update and reminder of selected surgical procedures for the general dental practitioner.

    • miR-101-5p Acts as a Tumor Suppressor in HER2-Positive Breast Cancer Cells and Improves Targeted Therapy 

      Normann, Lisa Svartdal; Haugen, Mads Haugland; Aure, Miriam Ragle; Kristensen, Vessela N.; Mælandsmo, Gunhild Mari; Sahlberg, Kristine Kleivi (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-01)
      Purpose: Human epidermal growth factor receptor 2 positive (HER2+) breast cancers responding poorly to targeted therapy need improved treatment options. miR-101-5p has shown tumor-suppressive properties in multiple cancer forms, and we assessed the effect and mechanism of action of this miRNA in HER2+ breast cancer.<p> <p>Methods: Expression levels of miR-101-5p in two clinical datasets, TCGA and ...

    • miR-126 as a prognostic marker in non-GIST soft tissue sarcoma 

      Persson, Magnus Lennart (Master thesis; Mastergradsoppgave, 2014-04-10)
      The aim of the study was to study the prognostic impact of miRNAs in non-GIST soft tissue sarcoma. The method used was microarray-based miRNA expression profiling of all verified human miRNAs on a selected number of samples. Selection criteria was time of survival (long and short). Then, the significance of miR-126 expression for disiease-specific survival in the total patient cohort of non-GIST ...

    • mir-34a targets cell cycle genes CCND1 (cyclin D1) and MYCN, while mir-21 does not target PTEN and PDCD4 in neuroblastoma 

      Utnes, Peter Andree (Master thesis; Mastergradsoppgave, 2013-06-03)
      Neuroblastoma is an embryonal cancer of the post-sympathetic nervous system and is the most frequent extra-cranial solid tumor in childhood. Two important microRNAs, the tumor suppressor mir-34a and the oncogenic mir-21, have been found to increase during MYCN-knockdown induced differentiation. However their distinct roles are not clear. This thesis employs a method to identify the mRNA targets of ...

    • MiR-493-5p attenuates the invasiveness and tumorigenicity in human breast cancer by targeting FUT4 

      Zhao, Lifen; Feng, Xiaobin; Song, Xiaobo; Zhou, Humin; Zhao, Yongfu; Cheng, Lei; Jia, Li (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-16)
      Breast cancer is a leading cause of cancer-related mortality among women. Altered fucosylation was found to be closely associated with tumorigenesis and metastasis of breast cancer. MicroRNAs (miRNAs) are important regulators of cell proliferation and metastasis, and aberrant miRNA expression has been observed in breast cancer. The present study aimed to evaluate the level of fucosyltransferase IV ...