English
norskBlar i tittel Artikler, rapporter og annet (medisinsk biologi)
Viser treff 401-420 av 1054
-
Halibut mitochondrial genomes contain extensive heteroplasmic tandem repeat arrays involved in DNA recombination
(Journal article; Tidsskriftartikkel; Peer reviewed, 2008-01-11)Background: Halibuts are commercially important flatfish species confined to the North Pacific and North Atlantic Oceans. We have determined the complete mitochondrial genome sequences of four specimens each of Atlantic halibut (Hippoglossus hippoglossus), Pacific halibut (Hippoglossus stenolepis) and Greenland halibut (Reinhardtius hippoglossoides), and assessed the nucleotide variability within ... -
Hazard Characterization of Modified Vaccinia Virus Ankara Vector: What Are the Knowledge Gaps?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-29)Modified vaccinia virus Ankara (MVA) is the vector of choice for human and veterinary applications due to its strong safety profile and immunogenicity in vivo. The use of MVA and MVA-vectored vaccines against human and animal diseases must comply with regulatory requirements as they pertain to environmental risk assessment, particularly the characterization of potential adverse effects to humans, ... -
The hazards of death by smoking in middle-aged women
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)Recent studies have found that the risk of death continues to increase among female smokers, as compared with women who have never smoked. We wanted to examine the effect of smoking on all-cause and causespecific mortality and calculate the corresponding population attributable fraction (PAF) of mortality in the Norwegian women and cancer study; a nationally representative prospective cohort ... -
HE4 is a novel tissue marker for therapy response and progestin resistance in medium- and low-risk endometrial hyperplasia
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-08-18)Background: The aim of the present study was to investigate whether changes in the tissue expression of human epididymisspecific protein 4 (HE4) could predict therapy resistance and relapse after progestin hormone therapy for medium- and low-risk endometrial hyperplasia.<p> <p>Methods: Endometrial biopsies were obtained from women participating in a multicentre RCT performed according to the ... -
Health and diseases of semi-domesticated reindeer in a climate change perspective
(Chapter; Bokkapittel, 2022-04-21)Climate change may affect reindeer herding and the health and disease of reindeer in several ways. One way of mitigating such changes is supplementary feeding, both in corrals and by bringing fodder to the animals on natural pastures. Feeding, when the right feed and feeding regime are used, may compensate for the loss of natural pastures and increase animal welfare. However, feeding may also cause ... -
Health and diseases of semi-domesticated reindeer in a climate change perspective
(Chapter; Bokkapittel, 2022-04-21)Climate change may affect reindeer herding and the health and disease of reindeer in several ways. One way of mitigating such changes is supplementary feeding, both in corrals and by bringing fodder to the animals on natural pastures. Feeding, when the right feed and feeding regime are used, may compensate for the loss of natural pastures and increase animal welfare. However, feeding may also cause ... -
Health and society in Chukotka: an overview
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)This study provides a historical overview of the changes in the socio-economic and health status of the population of Chukotka, from the Soviet to the post-Soviet period, with special attention paid to the circumstances of indigenous people. Past health studies in Chukotka are reviewed and key demographic and health indicator data presented. Since the 1990s, Chukotka’s population has shrunk to ... -
Health in overweight children: 2-year follow-up of Finnmark Activity School-a randomised trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014-11-20) -
The health of populations living in the indigenous minority settlements of northern Yakutia
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
The health related quality of life of people living with HIV/AIDS in sub-Saharan Africa - a literature review and focus group study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2010) -
Heart Angiotensin- Converting Enzyme and Angiotensin-Converting Enzyme 2 Gene Expression Associated With Male Sex and Salt-Sensitive Hypertension in the Dahl Rat.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-19)Angiotensin-converting enzyme 2 (ACE 2) in the heart including its sex dependency in the hypertensive heart, has not been much studied compared to ACE. In the present study, we used the Dahl salt-sensitive rat exposed to fructose and salt to model a hypertensive phenotype in males, females, and ovariectomized females. Blood pressure was measured by the tale-cuff technique in the conscious state. ... -
Heart Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 Gene Expression Associated With Male Sex and Salt-Sensitive Hypertension in the Dahl Rat
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-19)Angiotensin-converting enzyme 2 (ACE 2) in the heart including its sex dependency in the hypertensive heart, has not been much studied compared to ACE. In the present study, we used the Dahl salt-sensitive rat exposed to fructose and salt to model a hypertensive phenotype in males, females, and ovariectomized females. Blood pressure was measured by the tale-cuff technique in the conscious state. ... -
Heat for wounds - water filtered infrared-A for wound healing- a review.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-29)Background:<br>Water-filtered infrared-A (wIRA) is a special form of heat radiation with high tissue penetration and a low thermal load to the skin surface. wIRA corresponds to the major part of the sun’s heat radiation, which reaches the surface of the Earth in moderate climatic zones filtered by water and water vapour of the atmosphere. wIRA promotes healing of acute and chronic wounds both by ... -
Heavy decline of the largest European Arctic Skua Stercorarius parasiticus colony: interacting effects of food shortage and predation
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-24)Capsule: The number of breeding pairs of Europe’s largest Arctic Skua Stercorarius parasiticus colony at Slettnes, Norway, showed a dramatic decline of at least 50% over two decades, with food shortage in four years and increasing predation by Red Fox Vulpes vulpes leading to total breeding failure in five out of six recent study years.<p> Aims: To document the decline of Europe’s largest Arctic ... -
The Hematology of Tomorrow Is Here-Preclinical Models Are Not: Cell Therapy for Hematological Malignancies
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-24)The purpose of this review is to present the current knowledge on the clinical use of several forms of cell therapy in hematological malignancies and the preclinical models available for their study. In the context of allogeneic hematopoietic stem cell transplants, mesenchymal stromal cells are pursued to help stem cell engraftment and expansion, and control graft versus host disease. We further ... -
Hemodynamic effects of a soluble guanylate cyclase stimulator, Riociguat, and an activator, Cinaciguat, during NO-modulation in healthy pigs
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-14)Cardiovascular diseases are often characterized by dysfunctional endothelium. To compensate for the related lack of nitric oxide (NO), a class of soluble guanylate cyclase (sGC) stimulators and activators have been developed with the purpose of acting downstream of NO in the NO-sGC-cGMP cascade. These drugs have been discovered using photoaffinity labeling of sGC and high-throughput screening of a ... -
Hepatic disposal of advanced glycation end products during maturation and aging
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)Aging is characterized by progressive loss of metabolic and biochemical functions and accumulation of metabolic by-products, including advanced glycation end products (AGEs), which are observed in several pathological conditions. A number of waste macromolecules, including AGEs are taken up from the circulation by endocytosis mainly into liver sinusoidal endothelial cells (LSECs) and Kupffer cells ... -
Hepatitis B and C viruses and survival from hepatocellular carcinoma in the Arkhangelsk region: a Russian registry-based study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)Introduction. Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. The prevalence of hepatitis B (HBV) and C (HCV) in Russia was 7.6 and 5.4 per 100,000, respectively. The aim of this study was to assess the proportion of HCV and HBV infection among HCC patients, to evaluate associations between HCV, HBV and stage of HCC and to compare survival of HCC patients by their HBV/HCV ... -
High coffee consumption and different brewing methods in relation to postmenopausal endometrial cancer risk in the Norwegian women and cancer study: A population-based prospective study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014)<i>Background</i>: Coffee and its compounds have been proposed to inhibit endometrial carcinogenesis. Studies in the Norwegian population can be especially interesting due to the high coffee consumption and increasing incidence of endometrial cancer in the country.<p> <p><i>Methods</i>: A total of 97 926 postmenopausal Norwegian women from the population-based prospective Norwegian Women and ... -
High expression of CD20+ lymphocytes in soft tissue sarcomas is a positive prognostic indicator
(Journal article; Tidsskriftartikkel, 2012)The immune status is important in cancer patients. Tissue microarrays from 249 patients with soft tissue sarcomas were constructed. Immunohistochemistry was used to evaluate the CD3+, CD4+, CD8+, CD20+ and CD45+ lymphocytes in tumors. High density of CD20+ lymphocytes is an independent positive prognostic indicator for these patients.
