Browsing Artikler, rapporter og annet (medisinsk biologi) by Title

Now showing items 295-314 of 1054

    • Endoscopic full-thickness dissection (EFTD) in the rectum: a case series 

      Rushfeldt, Christian; Nordbø, M.; Steigen, Sonja Eriksson; Dehli, Trond; Gjessing, Petter Fosse; Norderval, Stig (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-28)
      Background Rectal endoscopic full- thickness dissection (EFTD) using a fexible colonoscope is an alternative to the wellestablished trans-anal endoscopic microsurgery (TEM) and the trans-anal minimally invasive surgery (TAMIS) techniques for resecting dysplastic or malignant rectal lesions. This study evaluated EFTD safety by analyzing outcomes of the frst patients to undergo rectal EFTD at the ...

    • Energy expenditure of free-living reindeer estimated by the doubly labelled water method. 

      Milne, Eric; Gotaas, Geir; Haggarty, Paul; Tyler, Nicholas J.C. (Journal article; Peer reviewed; Tidsskriftartikkel, 2000)

    • Enhanced T-lymphocyte infiltration in a desmoid tumor of the thoracic wall in a young woman treated with intratumoral injections of the oncolytic peptide LTX-315: a case report 

      Jebsen, Nina Louise; Apelseth, Torunn Oveland; Haugland, Hans Kristian; Rekdal, Øystein; Patel, Hamina; Gjertsen, Bjørn Tore; Jøssang, Dag Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-10)
      <p><i>Background - </i>Desmoid tumors are intermediary malignant, fibrous lesions occurring in various soft tissues. Surgical treatment is relentlessly challenging because of the propensity for local aggressive behavior and high risk of recurrence. Consequently, a wide range of oncological drugs and radiation therapy are being used; however, outcomes are unpredictable. We investigated whether local ...

    • Enterococcal Membrane Vesicles as Vaccine Candidates 

      Wagner, Theresa Maria; Romero-Saavedra, Felipe; Laverde, Diana; Johannessen, Mona Susan; Hübner, Johannes; Hegstad, Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-07)
      Enterococcus faecium is a leading cause of nosocomial infections, particularly in immunocompromised patients. The rise of multidrug-resistant E. faecium, including Vancomycin-Resistant Enterococci (VRE), is a major concern. Vaccines are promising alternatives to antibiotics, but there is currently no vaccine available against enterococci. In a previous study, we identified six protein vaccine ...

    • The enterococcus cassette chromosome, a genomic variation enabler in enterococci 

      Sivertsen, Audun; James Peter, Jessin Janice; Pedersen, Torunn Annie; Wagner, Theresa; Hegstad, Joachim; Hegstad, Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-07)
      Enterococcus faecium has a highly variable genome prone to recombination and horizontal gene transfer. Here, we have identified a novel genetic island with an insertion locus and mobilization genes similar to those of staphylococcus cassette chromosome elements SCCmec. This novel element termed the enterococcus cassette chromosome (ECC) element was located in the 3′ region of rlmH and encoded large ...

    • Enterococcus faecium produces membrane vesicles containing virulence factors and antimicrobial resistance related proteins 

      Wagner, Theresa; Joshi, Bishnu; James Peter, Jessin Janice; Askarian, Fatemeh; Skalko-Basnet, Natasa; Hagestad, Ole Christian; Mekhlif, Ahmed; Wai, Sun Nyunt; Hegstad, Kristin; Johannessen, Mona (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-30)
      <i>Enterococcus faecium</i> is a commensal but also a bacteremia causing pathogen, which is inherently resistant to several antimicrobials and has a great ability to acquire new traits. Bacterial membrane vesicles (MVs) are increasingly recognized as a mode of cell-free communication and a way to deliver virulence factors and/or antimicrobial resistance determinants. These features make MVs interesting ...

    • Enterococcus faecium TIR-Domain Genes Are Part of a Gene Cluster Which Promotes Bacterial Survival in Blood 

      Wagner, Theresa; James Peter, Jessin Janice; Paganelli, Fernanda; Willems, Rob J.L.; Askarian, Fatemeh; Pedersen, Torunn Annie; Top, Janetta; de Haas, Carla; van strijp, Jos A. G.; Johannessen, Mona; Hegstad, Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-03)
      <i>Enterococcus faecium</i> has undergone a transition to a multidrug-resistant nosocomial pathogen. The population structure of <i>E. faecium</i> is characterized by a sharp distinction of clades, where the hospital-adapted lineage is primarily responsible for bacteremia. So far, factors that were identified in hospital-adapted strains and that promoted pathogenesis of nosocomial <i>E. faecium</i> ...

    • Entrance and survival of Brucella pinnipedialis hooded seal strain in human macrophages and epithelial cells 

      Larsen, Anett Kristin; Nymo, Ingebjørg Helena; Briquemont, Benjamin; Sørensen, Karen Kristine; Godfroid, Jacques (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Marine mammal Brucella spp. have been isolated from pinnipeds (B. pinnipedialis) and cetaceans (B. ceti) from around the world. Although the zoonotic potential of marine mammal brucellae is largely unknown, reports of human disease exist. There are few studies of the mechanisms of bacterial intracellular invasion and multiplication involving the marine mammal Brucella spp. We examined the infective ...

    • Epidemiological and molecular characterization of Streptococcus pneumoniae carriage strains in pre-school children in Arkhangelsk, northern European Russia, prior to the introduction of conjugate pneumococcal vaccines 

      Jensen, V. Vorobieva S.; Furberg, Anne-Sofie; Slotved, Hans-Christian; Bazhukova, Tatiana; Haldorsen, Bjørg; Caugant, Dominique A.; Sundsfjord, Arnfinn; Valentiner-Branth, Palle; Simonsen, Gunnar Skov (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-15)
      <p><i>Background - </i>The 13-valent Pneumococcal Conjugate Vaccine (PCV-13) was introduced in the National Immunization Programme (NIP) schedule in Russia in March 2014. Previously, the 7-valent Pneumococcal Conjugate Vaccine (PCV-7) was marketed in Russia in 2009 but has never been offered for mass vaccination. A carriage study was performed among children in Arkhangelsk in 2006. The objective was ...

    • Epigenomic and transcriptomic approaches in the post-genomic era: Path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart 

      Perrino, Cinzia; Barabási, Albert-Laszló; Condorelli, Gianluigi; Davidson, Sean Michael; De Windt, Leon; Dimmeler, Stefanie; Engel, Felix Benedikt; Hausenloy, Derek John; Hill, Joseph Addison; Van Laake, Linda Wilhelmina; Lecour, Sandrine; Leor, Jonathan; Madonna, Rosalinda; Mayr, Manuel; Prunier, Fabrice; Sluijter, Joost Petrus Geradus; Schulz, Rainer; Thum, Thomas; Ferdinandy, Péter (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-29)
      Despite advances in myocardial reperfusion therapies, acute myocardial ischaemia/reperfusion injury and consequent ischaemic heart failure represent the number one cause of morbidity and mortality in industrialized societies. Although different therapeutic interventions have been shown beneficial in preclinical settings, an effective cardioprotective or regenerative therapy has yet to be successfully ...

    • ERBB3 is a marker of a ganglioneuroblastoma/ganglioneuroma-like expression profile in neuroblastic tumours 

      Wilzén, Annika; Krona, Cecilie; Sveinbjørnsson, Baldur; Kristiansson, Erik; Dalevi, Daniel; Øra, Ingrid; De Preter, Katleen; Stallings, Raymond L.; Maris, John; Versteeg, Rogier; Nilsson, Staffan; Kogner, Per; Abel, Frida (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Neuroblastoma (NB) tumours are commonly divided into three cytogenetic subgroups. However, by unsupervised principal components analysis of gene expression profiles we recently identified four distinct subgroups, r1-r4. In the current study we characterized these different subgroups in more detail, with a specific focus on the fourth divergent tumour subgroup (r4). Methods: Expression ...

    • Erfaringer med økonomiske støtteordninger for tannbehandling hos personer som er behandlet for hode-halskreft 

      Hadler-Olsen, Elin Synnøve (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11)
      Medlemmer i Munn- og halskreftforeningen mottok et spørreskjema for å kartlegge erfaringer med økonomiske refusjonsordninger for tannbehandling og kostnader til tannbehandling hos personer som er behandlet for hode-halskreft i Norge. I tillegg kartla vi utviklingen i Folketrygdens honorartakster for tannbehandling i perioden 2015-2020, og sammenlignet honorartakstene for 2021 med takstene for ...

    • ESC working group on cellular biology of the heart: Position paper for Cardiovascular Research: Tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure 

      Madonna, Rosalinda; Van Laake, Linda W.; Bøtker, Hans Erik; Davidson, Sean M.; De Caterina, Raffaele; Engel, Felix B.; Eschenhagen, Thomas; Fernandez-Aviles, Francesco; Hausenloy, Derek J.; Hulot, Jean-Sebastien; Lecour, Sandrine; Leor, Jonathan; Menasché, Philippe; Pesce, Maurizio; Perrino, Cinzia; Prunier, Fabrice; Van Linthout, Sophie; Ytrehus, Kirsti; Zimmermann, Wolfram-Hubertus; Ferdinandy, Péter; Sluijter, Joost P.G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-17)
      Morbidity and mortality from ischaemic heart disease (IHD) and heart failure (HF) remain significant in Europe and are increasing worldwide. Patients with IHD or HF might benefit from novel therapeutic strategies, such as cellbased therapies. We recently discussed the therapeutic potential of cell-based therapies and provided recommendations on how to improve the therapeutic translation of these ...

    • Estimating QUALY gains in applied studies: A review of cost-utility analyses published in 2010 

      Wisløff, Torbjørn; Hagen, Gunhild; Hamidi, Vida; Movik, Espen; Klemp, Marianne; Olsen, Jan Abel (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Estrogen receptors α and β and aromatase as independent predictors for prostate cancer outcome 

      Grindstad, Thea; Skjefstad, Kaja; Andersen, Sigve; Ness, Nora; Nordby, Yngve; Al-Saad, Samer; Fismen, Silje; Dønnem, Tom; Rakaee, Mehrdad; Busund, Lill-Tove; Bremnes, Roy M.; Richardsen, Elin (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-09)
      Androgens are considered important in normal prostate physiology and prostate cancer (PCa) pathogenesis. However, androgen-targeted treatment preventing PCa recurrence is still lacking. This indicates additional mediators contributing to cancer development. We sought to determine the prognostic significance of estrogen receptors, ERα and -β, and the aromatase enzyme in PCa. Tissue microarrays ...

    • Ethnic difference in the prevalence of angina pectoris in Sami and non-Sami populations: the SAMINOR study 

      Eliassen, Bent-Martin; Graff-Iversen, Sidsel; Melhus, Marita; Løchen, Maja-Lisa; Broderstad, Ann Ragnhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
      Objective: To assess the population burden of angina pectoris symptoms (APS), self-reported angina and a combination of these, and explore potential ethnic disparity in their patterns. If differences in APS were found between Sami and non-Sami populations, we aimed at evaluating the role of established cardiovascular risk factors as mediating factors. Design: Cross-sectional population-based ...

    • The european primary care monitor : structure, process and outcome indicators 

      Hasvold, Toralf; Kringos, Dionne S; Boerma, W; Bourgueil, Yann; Cartier, Thomas; Hutchinson, A; Lember, M; Oleszczyk, M; Pavlic, D; Svab, I; Tedeschi, P; Wilson, Andrew; Windak, A; Dedeu, T; Wilm, S (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)

    • Evaluation Challenges in the validation of B7-H3 as oral tongue cancer prognosticator 

      Sieviläinen, Meri; Wirsing, Anna Maria; Hyytiäinen, Aini; Almahmoudi, Rabeia; Rodrigues, Priscila; Bjerkli, Inger-Heidi; Åström, Pirjo; Toppila‑Salmi, Sanna; Paavonen, Timo; Coletta, Ricardo D.; Hadler‑Olsen, Elin; Salo, Tuula; Al‑Samadi, Ahmed (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-21)
      B7-H3 was the only molecule identified with prognostic potential from a recent systematic review of the prognostic value of immune checkpoints in oral cancer. We aimed to validate this finding in a multicenter international cohort. We retrospectively retrieved 323 oral tongue squamous cell carcinoma (OTSCC) samples from three different countries (Brazil, Finland, and Norway) for immunostaining and ...

    • Evaluation of Merkel Cell Polyomavirus DNA in Tissue Samples from italian Patients With Diagnosis of MCC 

      Prezioso, Carla; Carletti, Raffaella; Obregon, Francisco; Piacentini, Francesca; Maricone, Anna Maria; Soda, Giuseppe; Moens, Ugo; Di Gioia, Cira; Pietropaolo, Valeria (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-05)
      Because the incidence of Merkel cell carcinoma (MCC) has increased significantly during the last 10 years and it is recognized that Merkel cell polyomavirus (MCPyV) and ultraviolet (UV) radiation represent two different etiological inputs sharing clinical, histopathological, and prognostic similar features, although with different prognosis, this study investigated the detection of MCPyV in skin and ...

    • Evaluation of the One Health-Ness of 20 Years of Antimicrobial Resistance Surveillance in Norway 

      Norström, Madelaine; Simonsen, Gunnar Skov; Slettemeås, Jannice Schau; Furberg, Anne-Sofie; Urdahl, Anne Margrete (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-21)
      We evaluated the One Health-ness (OH-ness) of the surveillance system for antimicrobial resistance (AMR) in Norway by using the recently developed “Evaluation tool for One Health epidemiological surveillance capacities and capabilities” (OH–EpiCap tool). First, we defined the Norwegian AMR surveillance system that we would evaluate. The tool was applied by a group of stakeholders (key persons in the ...