Background and purpose: Several population-based cohort studies have related higher body mass index (BMI) to a decreased risk of subarachnoid hemorrhage (SAH). The main objective of our study was to investigate whether the previously reported inverse association can be explained by modifying effects of the most important risk factors of SAH—smoking and hypertension.<p> <p>Methods: We conducted ...

Background - The mortality of metabolic-obesity phenotypes has been thoroughly studied, but it is not known if or how the association between mortality and body mass index (BMI), waist circumference or a body shape index (ABSI) differ in strata of cardiometabolic health status.<p> <p>Methods - We linked data on 12,815 men and women aged 36–79 years from the SAMINOR 1 Survey with mortality data ...

Objectives: To examine the precision of imaging measures commonly used to assess mandibular morphology in children and adolescents with juvenile idiopathic arthritis (JIA). Secondly, to compare cone-beam computed tomography (CBCT) and magnetic resonance imaging (MRI) in the measurement of condylar height.<p> <p>Methods: Those included were children diagnosed with JIA during 2015–18 who had had ...

<i>Objective</i> - To assess the incidence of postdural puncture headache (PDPH) using 22-gauge atraumatic needle (Sprotte, 22GS) compared with 22-gauge traumatic needle (Quincke, 22GQ).<br><br> <i>Background</i> - Diagnostic lumbar puncture (dLP) is commonly complicated by PDPH. Despite evidence to support the use of 22GS, European neurologists seem to keep using 22GQ.<br><br> <i>Methods</i> ...

The acquisition of Antimicrobial Multidrug Resistance (AMR) in patients admitted to the Intensive Care Units (ICU) is a major global concern. This study analyses data in the form of multivariate time series (MTS) from 3476 patients recorded at the ICU of University Hospital of Fuenlabrada (Madrid) from 2004 to 2020. 18% of the patients acquired AMR during their stay in the ICU. The goal of ...

Background: Chronic headache causing severe headache-related disability for those affected by the disease is under- or misdiagnosed in many cases and therefore requires easy access to a specialist for optimal health care management.<p> <p>Objective: The goal of the research is to determine whether video consultations are noninferior to face-to-face consultations in treating chronic headache ...

Introduction:<br>Since the introduction of lumbar microdiscectomy in the 1970’s, many studies have attempted to compare the effectiveness of this method with that of standard open discectomy with conflicting results. This observational study is designed to compare the relative effectiveness of microdiscectomy (MD) with open discectomy (OD) for treating lumbar disc herniation, -within a large cohort, ...

Background To our current understanding, solid tumors depend on suppressed local immune reactions, often elicited by the interaction between tumor cells and tumor microenvironment (TME) components. Despite an improved understanding of anti-cancer immune responses in the TME, it is still unclear how immuno-suppressive TME are formed and how some cancer cells survive and metastasize.<p> <p>Methods ...

<p><i>Background: </i>China's two-child policy has led to a trend of aging in pregnancy which was associated with adverse outcomes. This study aimed to identify the clinically cutoff maternal age for adverse obstetric outcomes in China. <p><i>Methods: </i>This secondary analysis of a multicenter retrospective cohort study included data of childbearing women from 39 hospitals collected in urban China ...