Artikler, rapporter og annet (klinisk medisin): Nye registreringer

Viser treff 1561-1580 av 1974

    • Does concomitant methotrexate during rituximab treatment in granulomatosis with polyangiitis (Wegener's) increase the risk of severe infection? Comment on the article by Azar et al 

      Besada, Emilio; Diamantopoulos, Andreas P (Journal article; Tidsskriftartikkel, 2015-06-26)

    • Randomized trial of a novel game-based appointment system for a university hospital venereology unit: Study protocol 

      Gabarron, Elia; Fernandez-Luque, Luis; Serrano, Artur; Wynn, Rolf; Schopf, Thomas Roger Griesbeck (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-08)
      Background: Chlamydia is the most common reportable sexually transmitted disease (STD) in Norway, and its incidence in the two northernmost counties has been disclosed to be nearly the double of the Norwegian average. The latest publicly available rates showed that 85.6% of the new cases were diagnosed in people under 29 years old. The information and communication technologies are among the most ...

    • Impact of red cell distribution width on future risk of cancer and all-cause mortality among cancer patients – the Tromsø Study 

      Ellingsen, Trygve; Lappegård, Jostein; Skjelbakken, Tove; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10)

    • Quantitative home-based assessment of Parkinson’s symptoms: The SENSE-PARK feasibility and usability study 

      Ferreira, Joaquim J; Godinho, Catarina; Santos, Ana T.; Domingos, Josefa; Abreu, Daisy; Lobo, Raquel; Larsen, Frank Atle; Fagerbakke, Øyvind; Akeren, Ingvild; Wangen, Hilde; Serrano, Artur; Weber, Peter; Thoms, Andrea; Meckler, Stefan; Sollinger, Stefan; Uem, Janet van; Hobert, Markus A; Maier, Karin S; Matthew, Helen; Isaacs, Tom; Duffen, Joy; Graessner, Holm; Maetzler, Walter (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-06-10)
      Background: Currently, assessment of symptoms associated with Parkinson’s disease is mainly performed in the clinic. However, these assessments have limitations because they provide only a snapshot of the condition. <p>Methods: The feasibility and usability of an objective, continuous and relatively unobtrusive system (SENSE-PARK System), which consists of wearable sensors (three worn during the ...

    • Uric acid is associated with microalbuminuria and decreased glomerular filtration rate in the general population during 7 and 13 years of follow-up: The Tromsø Study 

      Storhaug, Hilde-Merete; Toft, Ingrid; Norvik, Jon Viljar; Jenssen, Trond Geir; Eriksen, Bjørn Odvar; Melsom, Toralf; Løchen, Maja-Lisa; Solbu, Marit Dahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12-11)
      Background: The role of uric acid in development of renal dysfunction (RD) remains controversial. Earlier studies have reported inconsistent results, possibly because of their varying ability to adjust for confounding. The impact of longitudinal change in uric acid on renal outcome has not been assessed previously. We aimed to study the impact of change in serum uric acid (SUA) as well as baseline ...

    • Mortality and one-year functional outcome in elderly and very old patients with severe traumatic brain injuries: observed and predicted 

      Røe, Cecilie; Skandsen, Toril; Manskow, Unn Sollid; Ader, Tiina; Anke, Audny (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11)
      The aim of the present study was to evaluate mortality and functional outcome in old and very old patients with severe traumatic brain injury (TBI) and compare to the predicted outcome according to the internet based CRASH (Corticosteroid Randomization After Significant Head injury) model based prediction, from the Medical Research Council (MRC). Methods. Prospective, national multicenter study ...

    • Inflammatory response after laparoscopic versus open resection of colorectal liver metastases: Data from the oslo-comet trial 

      Fretland, Åsmund Avdem; Sokolov, Andrey; Postriganova, Nadezda; Kazaryan, Airazat M.; Pischke, Søren Erik; Nilsson, Per; Rognes, Ingrid Nygren; Bjørnbeth, Bjørn Atle; Fagerland, Morten; Mollnes, Tom Eirik; Edwin, Bjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10)
      Laparoscopic and open liver resection have not been compared in randomized trials. The aim of the current study was to compare the inflammatory response after laparoscopic and open resection of colorectal liver metastases (CLM) in a randomized controlled trial. This was a predefined exploratory substudy within the Oslo CoMetstudy. Forty-five patients with CLM were randomized to laparoscopic (n ...

    • Early intervention influences positively quality of life as reported by prematurely born children at age nine and their parents; a randomized clinical trial 

      Landsem, Inger Pauline; Handegård, Bjørn Helge; Ulvund, Stein Erik; Kaaresen, Per Ivar; Rønning, John Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-22)
      Background: The Tromsø Intervention Study on Preterms evaluates an early, sensitizing intervention given to parents of prematurely born children (birth-weight < 2000 g). The current study investigated the potential influence of the intervention on children’s self-reported and parental proxy-reported quality of life (QoL) at children’s age of nine. <p>Methods: Participants were randomized to either ...

    • Is there a weekly pattern for health information searching and is the pattern unique to health topics? 

      Gabarron, Elia; Lau, Annie YS; Wynn, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12)
      Background: Online health information–seeking behaviors have been reported to be more common at the beginning of the workweek. This behavior pattern has been interpreted as a kind of “healthy new start” or “fresh start” due to regrets or attempts to compensate for unhealthy behavior or poor choices made during the weekend. However, the observations regarding the most common health information–seeking ...

    • Ketamine for prehospital trauma analgesia in a low-resource rural trauma system: a retrospective comparative study of ketamine and opioid analgesia in a ten-year cohort in Iraq 

      Losvik, Ole Kristian; Murad, Mudhafar Kareem; Skjerve, Eystein; Husum, Hans (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-09)
      Background Opioid analgesics are used in most trauma systems, and only a few studies report on the use of ketamine for prehospital analgesia. In a low-cost rural trauma system in Iraq paramedics have been using prehospital ketamine analgesia for ten years. This study aims to evaluate the effects of prehospital analgesia on physiologic trauma severity indicators and compare the effect of ketamine ...

    • Relationship between the quality of service provided through store-and-forward telemedicine consultations and the difficulty of the cases – implications for long-term quality assurance 

      Wootton, Richard; Liu, Joanne; Bonnardot, Laurent (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-09-25)
      We examined the difficulty of telemedicine cases and the quality of the resultant consultation in a mature store-and-forward telemedicine network. A random sample of 10 telemedicine cases was selected from those occurring over a 3-month period (5% of the workload) and they were scored by three experienced observers. Inter-observer agreement on the difficulty scores was poor (Fleiss’s kappa = 0.18) ...

    • Experience with quality assurance in two store-and-forward telemedicine networks 

      Wootton, Richard; Liu, Joanne; Bonnardot, Laurent; Venugopal, Raghu; Oakley, Amanda (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-26)
      Despite the increasing use of telemedicine around the world, little has been done to incorporate quality assurance (QA) into these operations. The purpose of the present study was to examine the feasibility of QA in store-and-forward teleconsulting using a previously published framework. During a 2-year study period, we examined the feasibility of using QA tools in two mature telemedicine networks ...

    • Cancer-associated fibroblasts from lung tumors maintain their immunosuppressive abilities after high-dose irradiation 

      Gorchs, Laia; Hellevik, Turid; Bruun, Jack-Ansgar; Camilio, Ketil Andre; Al-Saad, Samer; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-05-12)
      Accumulating evidence supports the notion that high-dose (>5 Gy) radiotherapy (RT) regimens are triggering stronger pro-immunogenic effects than standard low-dose (2 Gy) regimens. However, the effects of RT on certain immunoregulatory elements in tumors remain unexplored. In this study, we have investigated the effects of high-dose radiotherapy (HD-RT) on the immunomodulating functions of cancer-associated ...

    • Prognostic impact of CXCL16 and CXCR6 in non-small cell lung cancer: Combined high CXCL16 expression in tumor stroma and cancer cells yields improved survival 

      Hald, Sigurd; Kiselev, Yury; Al-Saad, Samer; Richardsen, Elin; Johannessen, Charles; Eilertsen, Marte; Kilvær, Thomas Karsten; Al-Shibli, Khalid; Andersen, Sigve; Busund, Lill-Tove; Bremnes, Roy M.; Dønnem, Tom (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-05-29)
      Background: The chemokine CXCL16 and its receptor CXCR6 are expressed by a variety of immune cells and have been shown to influence angiogenesis. The expression of CXCR6 and CXCL16 has been examined in numerous human cancers; however no studies have yet investigated their influence on prognosis in non-small cell lung cancer (NSCLC). We aimed to explore their prognostic significance in NSCLC, in ...

    • Polymorphisms on PAI-1 and ACE genes in association with fibrinolytic bleeding after on-pump cardiac surgery 

      Ozolina, Agnese; Strike, Eva; Nikitina-Zake, Liene; Jaunalksne, Inta; Krumina, Angelika; Lacis, Romans; Bjertnæs, Lars J.; Vanags, Indulis (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-09-04)
      Background: Carriers of plasminogen activator inhibitor -1 (PAI-1) -675 genotype 5G/5G may be associated with lower preoperative PAI-1 plasma levels and higher blood loss after heart surgery using cardiopulmonary bypass (CPB). We speculate if polymorphisms of PAI-1 -844 A/G and angiotensin converting enzyme (ACE) intron 16 I/D also might promote fibrinolysis and increase postoperative bleeding. ...

    • Scientific impact of studies published in temporarily available radiation oncology journals: a citation analysis 

      Nieder, Carsten; Geinitz, Hans; Andratschke, Nikolaus H.; Grosu, Anca-Ligia (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-24)
      The purpose of this study was to review all articles published in two temporarily available radiation oncology journals (Radiation Oncology Investigations, Journal of Radiosurgery) in order to evaluate their scientific impact. From several potential measures of impact and relevance of research, we selected article citation rate because landmark or practice-changing research is likely to be cited ...

    • Training frontline workforce on psychosis management: a prospective study of training effects 

      Sørlie, Tore; Borg, Marit; Flage, Karin; Kolbjørnsrud, Ole Bjørn; Haugen, Gunnar; Saltyte Benth, Jurate; Ruud, Torleif (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-19)
      Background: The care situation for persons experiencing severe mental illness is often complex and demands good coordination, communication, and interpersonal relationships among those involved from the primary and special‑ ized mental health care systems. For 15 years, professional care providers from different service levels within the same geographical areas in Norway have been trained ...

    • The Significance of Emotions and Professional Relations for Accommodating a Web-Based Ulcer Record and Improving Home-Based Care 

      Ekeland, Anne G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-01-22)
      Evidence of technological performance, medical improvements and economic effectiveness is generally considered sufficient for judging advances in healthcare. In this paper, I aim to add knowledge about the ways human emotions and professional relations play roles in the processes of accommodating new technologies for quality improvements. A newly-implemented, web-based ulcer record service for ...

    • Regional differences in renal replacement therapy in northern Norway 2000-2012 

      Norum, Jan; Leivestad, Torbjørn; Eriksen, Bjørn Odvar; Skår, Siw; Fagerheim, Anne Kristine; Reisæter, Anna Varberg (Journal article; Tidsskriftartikkel, 2015-02-10)
      Objectives: Distance from residence location to a centre for renal replacement therapy (RRT) may influence patients’ quality of life and prognosis. Northern Norway constitutes 45% of Norway’s landmass, but has less than 10% of the population. <p>Methods: In this study, we analysed all patients in northern Norway consecutively registered in the Norwegian Renal Registry during 20002012. A total ...

    • The treatment of spleen injuries: a retrospective study 

      Dehli, Trond; Bågenholm, Anna; Trasti, Nora; Monsen, Svein Arne; Bartnes, Kristian (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10-29)
      Background Hemorrhage after blunt trauma is a major contributor to death after trauma. In the abdomen, an injured spleen is the most frequent cause of major bleeding. Splenectomy is historically the treatment of choice. In 2007, non-operative management (NOM) with splenic artery embolization (SAE) was introduced in our institution. The indication for SAE is hemodynamically stable patients with ...