• Adverse Pregnancy Outcomes among Adolescents in Northwest Russia: A Population Registry-Based Study 

      Usynina, Anna Aleksandrovna; Postoev, Vitaly; Odland, Jon Øyvind; Grjibovski, Andrej (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-03)
      This study aimed to assess whether adolescents have an increased risk of adverse pregnancy outcomes (APO) compared to adult women. We used data on 43,327 births from the population-based Arkhangelsk County Birth Registry, Northwest Russia, for 2012–2014. The perinatal outcomes included stillbirth, preterm birth (<37 and <32 weeks), low and very low birthweight, 5 min Apgar score <7 and <4, ...
    • The Apolipoprotein B/Apolipoprotein A-I Ratio as a Potential Marker of Plasma Atherogenicity 

      Kaneva, Anastasiya M.; Potolitsyna, Natalya N.; Bojko, Evgeny R.; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2015)
      Background. The apolipoprotein (apo) B/apoA-I ratio represents the balance between apoB-rich atherogenic particles and apoAI-rich antiatherogenic particles, and this ratio is considered to be a marker of cardiovascular risk. Although many studies have demonstrated the importance of the apoB/apoA-I ratio in predicting the presence or absence of cardiovascular disease, less is known about apoB/apoA-I ...
    • The Argentinian mother-and-child contaminant study: a cross-sectional study among delivering women in the cities of Ushuaia and Salta 

      Økland, Inger; Odland, Jon Øyvind; Matiocevich, Silvinia; Alvarez, Marisa Viviana; Aarsland, Torbjørn; Nieboer, Evert; Hansen, Solrunn (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-28)
      Several ongoing international multidisciplinary projects have examined linkages between environmental chemicals and health. In contrast to Arctic regions, information for the Southern Hemisphere is scarce. Because of the inherent practice of pesticide utilisation and mismanagement, food security is potentially threatened. The most vulnerable period in human life occurs during pregnancy and early ...
    • Assessing the relationship between perfluoroalkyl substances, thyroid hormones and binding proteins in pregnant women; a longitudinal mixed effects approach 

      Berg, Vivian; Nøst, Therese Haugdahl; Hansen, Solrunn; Elverland, Astrid; Veyhec, Anna-Sofía; Jorde, Rolf; Odland, Jon Øyvind; Sandanger, Torkjel M (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04)
      <p>The mechanisms involved in thyroid homeostasis are complex, and perfluoroalkyl substances (PFASs) have been indicated to interfere at several levels in this endocrine system. Disruption of the maternal thyroid homeostasis during early pregnancy is of particular concern, where subclinical changes in maternal thyroid hormones (THs) may affect embryonic and foetal development.</p> <p>The present ...
    • Azithromycin versus placebo for the treatment of HIV-associated chronic lung disease in children and adolescents (BREATHE trial): study protocol for a randomised controlled trial 

      Gonzalez-Martinez, Carmen; Kranzer, Katharina; McHugh, Grace; Corbett, Elizabeth L.; Mujuru, Hilda A.; Nicol, Mark P; Rowland-Jones, Sarah; Rehman, Andrea M.; Gutteberg, Tore Jarl; Flægstad, Trond; Odland, Jon Øyvind; Ferrand, Rashida (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-28)
      Background<br> Human immunodeficiency virus (HIV)-related chronic lung disease (CLD) among children is associated with substantial morbidity, despite antiretroviral therapy. This may be a consequence of repeated respiratory tract infections and/or dysregulated immune activation that accompanies HIV infection. Macrolides have anti-inflammatory and antimicrobial properties, and we hypothesised that ...
    • Benefit and risk assessment of breastmilk for infant health in Norway 

      Meltzer, Helle Margrete; Knutsen, Helle Katrine; Skåre, Janneche Utne; Brandtzæg, Per; Torheim, Liv Elin; Odland, Jon Øyvind; Løland, Beate Fossum (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-20)
      The present benefit and risk assessment of breastmilk and contaminants in breastmilk was initiated by the Norwegian Scientific Committee for Food Safety (VKM). The overall objective is to provide a balanced assessment of the benefits of breastmilk against the possible risks from exposure to contaminants in breastmilk with focus on Norwegian conditions. The aim is to contribute to a foundation for ...
    • Benefit and risk assessment of breastmilk for infant health in Norway: Opinion of the Steering Committee of the Norwegian Scientific Committee for Food Safety 

      Meltzer, Helle Margrete; Brandtzæg, Per; Knutsen, Helle Katrine; Løland, Beate Fossum; Odland, Jon Øyvind; Skåre, Janneche Utne; Torheim, Liv Elin; Amlund, Heidi; Arukwe, Augustine; Bernhoft, Aksel; Brantsæter, Anne Lise; Dierkes, Jutta; Eggesbø, Merete Åse; Eriksen, Gunnar Sundstøl; Frølich, Wenche; Frøyland, Livar; Fæste, Christiane Kruse; Halvorsen, Ragnhild; Haugen, Margaretha; Hemre, Gro Ingunn; Iversen, Per Ole; Krogdahl, Åshild; Lassen, Jørgen Fredrik; Lindemann, Rolf; Lyche, Jan Ludvig; Mansoor, Mohammad Azam; Nerland, Audun Helge; Næss, Bjørn; Ruus, Anders; Skålhegg, Bjørn Steen; Steffensen, Inger-Lise; Sundheim, Leif; Sverdrup, Line Emilie; Thomsen, Cathrine; Østerås, Olav; Alexander, Jan (Research report; Forskningsrapport, 2013-12-12)
      Breastmilk covers all the nutritional needs of the infant the first months of life, with the exception of vitamin D. In addition, breastmilk has a number of protective properties. However, as humans are exposed to polluting chemicals through food, air, water and skin contact, breastmilk also contains contaminants. Taking the present-day levels of contaminants in Norwegian breastmilk and the long ...
    • Carotid intima media thickness in older childrenand adolescents with HIV taking antiretroviraltherapy 

      Majonga, Edith D.; Chiesa, Scott T.; McHough, Grace; Mujuru, Hilda; Nathoo, Kusum; Odland, Jon Øyvind; Kaski, Juan Pablo; Ferrand, Rashida A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04)
      Increased carotid intima-media thickness (cIMT) is reported in both adults and children with human immunodeficiency virus (HIV) in high income settings and is associated with an increased risk of cardiovascular disease, but data from sub-Saharan Africa is lacking.<p> <p>We assessed cIMT using ultrasound in perinatally HIV-infected children aged 6 to 16 years taking antiretroviral therapy (ART) ...
    • Changes in detection of birth defects and perinatal mortality after introduction of prenatal ultrasound screening in the Kola Peninsula (North-West Russia): combination of two birth registries 

      Postoev, Vitaly Alexandrovich; Grjibovski, Andrej; Nieboer, Evert; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-23)
      Background: Prenatal diagnostics ultrasound was established in Russia in 2000 as a routine method of screening for birth defects. The aims of the current study were twofold: to assess changes in birth defects prevalence at birth and perinatal mortality after ultrasound screening was implemented and to estimate prenatal detection rates for congenital malformations in the city of Monchegorsk (Murmansk ...
    • Composition of gut microbiota of children and adolescents with perinatal HIV infection taking antiretroviral therapy in Zimbabwe 

      Flygel, Trym Thune; Sovershaeva, Evgeniya; Classen-Weitz, Shantelle; Hjerde, Erik; Mwaikono, Kilaza S.; Odland, Jon Øyvind; Ferrand, Rashida A.; McHugh, Grace; Gutteberg, Tore Jarl; Nicol, Mark P.; Cavanagh, Jorunn Pauline; Flægstad, Trond (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-24)
      <p><i>Background - </i>Human immunodeficiency virus (HIV) infection causes impairment of the gastrointestinal barrier, with substantial depletion of CD4<sup>+</sup> T cells in the gut. Antiretroviral therapy (ART) restores CD4<sup>+</sup> counts and may have beneficial effects on gut microbiota in adults. Little is known about effect of long-term ART on gut microbiome in HIV-infected children. We ...
    • Congenital anomalies of the kidney and the urinary tract: A murmansk county birth registry study 

      Postoev, Vitaly Alexandrovich; Grjibovski, Andrej; Kovalenko, Anton Alexandrovich; Anda, Erik Eik; Nieboer, Evert; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-02-02)
      BACKGROUND: Congenital anomalies of the kidney and the urinary tract (CAKUTs) are relatively common birth defects. The combined prevalence in Europe was 3.3 per 1000 in 2012. The risk factors for these anomalies are not clearly identified. The aims of our study were to calculate the birth prevalences of urinary malformations in Murmansk County during 2006 to 2011 and to investigate related prenatal ...
    • Contamination index. A novel parameter for metal and pesticide analyses in maternal blood and umbilical cord 

      Motta, Ilse Sodré; Volpato, Gustavo Tadeu; Damasceno, Débora Cristina; Sinzato, Yuri Karen; Vesentini, Giovana; Rudge, Cibele Vicira Cunha; Calderon, Iracema Mattos Paranhos; Kempinas, Wilma de Grava; Odland, Jon Øyvind; Rudge, Marilza Vieira Cunha (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-07)
      PURPOSE:<br> To evaluate the contamination index of metals and pesticides in pregnant women, and to relate this to perinatal outcomes. <br> METHODS:<br> Descriptive, retrospective, exploratory study, developed from existing secondary data analyses at Level III maternity center. A total of 40 mothers with their newborns (NB), living in a rural area in Botucatu- Brazil and surrounding region. ...
    • Design and validity of a questionnaire to assess sexuality in pregnant women 

      Rudge, Cibele V. C.; Calderon, Iracema M. P.; Odland, Jon Øyvind; Dias, Adriano; Lopes, Gerson P.; Rudge, Marilza V. C.; Barbosa, Angélica P.; Maestá, Izildinha (Journal article; Tidsskriftartikkel; Peer reviewed, 2009-07-29)
      Background: A review of validated methods for assessing female sexual dysfunction and a review of male and female sexual dysfunction did not refer to any specific questionnaire for evaluating sexuality during pregnancy. A study was performed at the Obstetrics and Gynecology Department of Botucatu Medical School, São Paulo State University, Brazil to design and validate a pregnancy sexuality ...
    • Do Cervical Cancer Patients Diagnosed with Opportunistic Screening Live Longer? An Arkhangelsk Cancer Registry Study 

      Roik, Elena Evgenievna; Nieboer, Evert; Kharkova, Olga Alexandrovna; Grjibovski, Andrej; Postoev, Vitaly Alexandrovich; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-26)
      The aim of the current study was to compare cervical cancer (СС) patients diagnosed with and without screening in terms of: (i) sociodemographic and clinical characteristics; (ii) factors associated with survival; and (iii), and levels of risk. A registry-based study was conducted using data from the Arkhangelsk Cancer Registry. It included women with newly diagnosed malignant neoplasm of the uterine ...
    • Effect of Smoking Behavior before and during Pregnancy on Selected Birth Outcomes among Singleton Full-Term Pregnancy: A Murmansk County Birth Registry Study 

      Kharkova, Olga Alexandrovna; Grjibovski, Andrej M; Krettek, Alexandra; Nieboer, Evert; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-02)
      The aim of our study was to assess associations between smoking behavior before and during pregnancy and selected adverse birth outcomes. This study is based on the Murmansk County Birth Registry (MCBR). Our study includes women who delivered a singleton pregnancy after 37 weeks of gestation (N = 44,486). Smoking information was self-reported and assessed at the first antenatal visit during pregnancy. ...
    • Estimating Time-Varying PCB Exposures Using Person-Specific Predictions to Supplement Measured Values: A Comparison of Observed and Predicted Values in Two Cohorts of Norwegian Women 

      Nøst, Therese Haugdahl; Breivik, Knut; Wania, Frank; Rylander, Charlotta; Odland, Jon Øyvind; Sandanger, Torkjel M (Journal article; Tidsskriftartikkel; Peer reviewed, 2015)
      Background: Studies on the health effects of polychlorinated biphenyls (PCBs) call for an understanding of past and present human exposure. Time-resolved mechanistic models may supplement information on concentrations in individuals obtained from measurements and/or statistical approaches if they can be shown to reproduce empirical data. <p>Objectives: Here, we evaluated the capability of one ...
    • Factors associated with maternal serum levels of perfluoroalkyl substances and organochlorines: A descriptive study of parous women in Norway and Sweden 

      Lauritzen, Hilde Brun; Larose, Tricia L; Øien, Torbjørn; Odland, Jon Øyvind; van de Bor, Margot; Jacobsen, Geir Wenberg; Sandanger, Torkjel M (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-08)
      <b>Introduction</b><br> Perfluoroalkyl substances (PFASs) and organochlorines (OCs) are ubiquitous and persistent in the environment and proposed endocrine disrupting chemicals (EDCs). They can be transferred across the placenta during pregnancy, and studies suggest that the prenatal period may be particularly sensitive for influences on fetal growth and development. Several studies have ...
    • First-trimester smoking cessation in pregnancy did not increase the risk of preeclampsia/eclampsia: A Murmansk County Birth Registry study 

      Kharkova, Olga Alexandrovna; Grjibovski, Andrej M; Krettek, Alexandra; Nieboer, Evert; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-10)
      Although prior studies have shown that smoking reduces preeclampsia/eclampsia risk, the consequence of giving up this habit during pregnancy should be assessed. The aims of the current study were threefold: (i) describe maternal characteristics of women with preeclampsia/ eclampsia; (ii) examine a possible association between the number of cigarettes smoked daily during pregnancy and the development ...
    • Health effects associated with measured levels of contaminants in the Arctic 

      Weihe, Pál; Debes, Frodi; Halling, Jónrit; Petersen, Maria Skaalum; Muckle, Gina; Odland, Jon Øyvind; Dudarev, Alexey; Ayotte, Pierre; Dewailly, Éric; Grandjean, Philippe; Bonefeld-Jørgensen, Eva (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-13)
      The Human Health Assessment Group has over the past decade recommended that effect studies be conducted in the circumpolar area. Such studies examine the association between contaminant exposure in the Arctic populations and health effects. Because foetuses and young children are the most vulnerable, effect studies are often prospective child cohort studies. The emphasis in this article is on a ...
    • High HIV and active tuberculosis prevalence and increased mortality risk in adults with symptoms of TB: a systematic review and meta-analyses 

      Nliwasa, Marriot; MacPherson, Peter; Gupta-Wright, Ankur; Mwapasa, Mphatso; Horton, Katherine; Odland, Jon Øyvind; Flach, Clare; Corbett, Elizabeth L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-31)
      <i>Introduction</i>: HIV and tuberculosis (TB) remain leading causes of preventable death in low- and middle-income countries(LMICs). The World Health Organization (WHO) recommends HIV testing for all individuals with TB symptoms, but implementation has been suboptimal. We conducted a systematic literature review and meta-analyses to estimate HIV and TB prevalence, and short-term (two to six months) ...