Viser treff 513-532 av 1054

    • Inter-rater reliability of a national acute stroke register 

      Varmdal, Torunn; Ellekjær, Hanne; Fjærtoft, Hild; Indredavik, Bent; Lydersen, Stian; Bønaa, Kaare Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10-19)
      <p>Background: Medical quality registers are useful sources of knowledge about diseases and the health services. However, there are challenges in obtaining valid and reliable data. This study aims to assess the reliability in a national medical quality register. <p>Methods: We randomly selected 111 patients having had a stroke in 2012. An experienced stroke nurse completed the Norwegian Stroke ...
    • The interaction between Staphylococcus aureus SdrD and desmoglein 1 is important for adhesion to host cells 

      Askarian, Fatemeh; Ajayi, Clement; Hanssen, Anne-Merethe; Van Sorge, Nina M.; Pettersen, Ingvild; Diep, Dzung Bao; Sollid, Johanna U. Ericson; Johannessen, Mona (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-02-29)
      <i>Staphylococcus aureus</i> is known as a frequent colonizer of the skin and mucosa. Among bacterial factors involved in colonization are adhesins such as the microbial surface components recognizing adhesive matrix molecules (MSCRAMMs). Serine aspartate repeat containing protein D (SdrD) is involved in adhesion to human squamous cells isolated from the nose. Here, we identify Desmoglein 1 ...
    • The Interaction Between Venous Thromboembolism and Socioeconomic Status on the Risk of Disability Pension 

      Jørgensen, Helle; Horváth-Puhó, Erzsébet; Laugesen, Kristina; Brækkan, Sigrid Kufaas; Hansen, John Bjarne; Sørensen, Henrik Toft (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-14)
      Background: Venous thromboembolism (VTE) is associated with increased risk of disability pension. How socioeconomic status (SES) impacts the risk of disability pension after a VTE is unknown. The aim of this nationwide population based cohort study to investigate the interaction between SES and incident VTE on the risk of subsequent disability pension.<p> <p>Methods: Using Danish national medical ...
    • Interleukin-1β as emerging therapeutic target in hematological malignancies and potentially in their complications 

      Arranz, Lorena; Arriero Sanchez, Maria Del Mar; Villatoro, Alicia (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-03)
      Interleukin-1β (IL-1β) is a pleiotropic cytokine that exerts multiple roles in both physiological and pathological conditions. It is produced by different cell subsets, and drives a wide range of inflammatory responses in numerous target cells. Enhanced IL-1β signaling is a common event in patients of hematological malignancies. Recent body of evidence obtained in preclinical models shows the ...
    • The International Collaboration on Complementary Therapy Resources (ICCR) : working together to improve online CAM information 

      Pilkington, Karen; Gamst, are; Liu, Irene; Ostermann, Thomas; Pinto, Dimitry; Richardon, Janet (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Use of the Internet to find health information is increasing dramatically but the quality of information, particularly on complementary and alternative medicine (CAM) is variable. The International Collaboration on Complementary Therapy Resources (ICCR) involves collaboration between the national CAM information centers in Australia, Denmark, Norway, the United Kingdom, and the United States, and a ...
    • Interobserver Reliability of Four Diagnostic Methods Using Traditional Korean Medicine for Stroke Patients 

      Lee, Ju Ah; Ko, Mi Mi; Kang, Byoung-Kab; Alræk, Terje; Birch, Stephen; Lee, Myeong S. (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Interplay of immune and kidney resident cells in the formation of tertiary lymphoid structures in lupus nephritis 

      Jamaly, Simin; Rakaee, Mehrdad; Abdi, Reza; tsokos, George; Fenton, Kristin Andreassen (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-27)
      Kidney involvement confers significant morbidity and mortality in patients with systemic lupus erythematosus (SLE). The pathogenesis of lupus nephritis (LN) involves diverse mechanisms instigated by elements of the autoimmune response which alter the biology of kidney resident cells. Processes in the glomeruli and in the interstitium may proceed independently albeit crosstalk between the two is ...
    • The interplay of matrix metalloproteinase-8, transforming growth factor-β1 and vascular endothelial growth factor-C cooperatively contributes to the aggressiveness of oral tongue squamous cell carcinoma 

      Åström, Pirjo; Juurikka, Krista; Hadler-Olsen, Elin Synnøve; Svineng, Gunbjørg; Cervigne, Nilva K.; Coletta, Ricardo D.; Risteli, Juha; Kauppila, Joonas H.; Skarp, Sini; Kuttner, Samuel; Oteiza, Ana; Sutinen, Meeri; Salo, Tuula (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-03)
      Background: Matrix metalloproteinase-8 (MMP-8) has oncosuppressive properties in various cancers. We attempted to assess MMP-8 function in oral tongue squamous cell carcinoma (OTSCC).<p> <p>Methods: MMP-8 overexpressing OTSCC cells were used to study the effect of MMP-8 on proliferation, apoptosis, migration, invasion and gene and protein expression. Moreover, MMP-8 functions were assessed in the ...
    • Intestinal fungi are causally implicated in microbiome assembly and immune development in mice 

      van Tilburg Bernardes, Erik; Pettersen, Veronika Kucharova; W. Gutierrez, Mackenzie; Isabelle, Laforest-Lapointe; Marie-Claire, Arrieta (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-22)
      The gut microbiome consists of a multi-kingdom microbial community. Whilst the role of bacteria as causal contributors governing host physiological development is well established, the role of fungi remains to be determined. Here, we use germ-free mice colonized with defined species of bacteria, fungi, or both to differentiate the causal role of fungi on microbiome assembly, immune development, ...
    • Intra-cellular to inter-organ mitochondrial communication in striated muscle in health and disease 

      Boardman, Neoma Tove; Wüst, Rob C.I. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-02)
      Mitochondria sense both biochemical and energetic input in addition to communicating signals regarding the energetic state of the cell. Increasingly, these signaling organelles are recognized as key for regulating different cell functions. This review summarizes recent advances in mitochondrial communication in striated muscle, with specific focus on the processes by which mitochondria communicate ...
    • Intracellular MMP-2 Activity in Skeletal Muscle is Associated with Type II Fibers 

      Hadler-Olsen, Elin Synnøve; Solli, Ann Iren; Hafstad, Anne Dragøy; Winberg, Jan-Olof; Uhlin-Hansen, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-09-29)
      Matrix metalloproteinase 2 (MMP-2) is a proteolytic enzyme implicated in motility, differentiation, and regeneration of skeletal muscle fibers through processing of extracellular substrates. Although MMP-2 has been found to be localized intracellularly in cardiomyocytes where the enzyme is thought to contribute to post-ischemic loss of contractility, little is known about intracellular MMP-2 activity ...
    • Intraregional hospital outbreak of OXA-244-producing Escherichia coli ST38 in Norway, 2020 

      Lindemann, Paul Christoffer; Pedersen, Torunn Annie; Oma, Dorthea Hagen; Janice, Jessin; Grøvan, Fredrik; Chedid, Ghantous Milad; Hafne, Liv Jorunn; Josefsen, Ellen Haldis; Kacelnik, Oliver; Sundsfjord, Arnfinn; Samuelsen, Ørjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-06)
      Infections with OXA-244-carbapenemase-producing Escherichia coli with sequence type (ST)38 have recently increased in Europe. Due to its low-level activity against carbapenems, OXA-244 can be difficult to detect. Previous assessments have not revealed a clear source and route of transmission for OXA-244-producing E. coli, but there are indications of non-healthcare related sources and community ...
    • Introduktion: Arbejde – sundhed og sygdom 

      Vinther Nielsen, Claus; Wind, Gitte; Risør, Mette Bech (Journal article; Tidsskriftartikkel, 2012)
      I dette temanummer kigger vi nærmere på forholdet mellem arbejde, sundhed og sygdom.
    • Investigating the mobilome in clinically important lineages of Enterococcus faecium and Enterococcus faecalis 

      Mikalsen, Theresa; Pedersen, Torunn Annie; Willems, Rob J; Coque, Teresa M.; Werner, Guido; Sadowy, Eva; van Schaik, Willem; Jensen, Lars Bogø; Sundsfjord, Arnfinn; Hegstad, Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-10)
      Background: The success of Enterococcus faecium and E. faecalis evolving as multi-resistant nosocomial pathogens is associated with their ability to acquire and share adaptive traits, including antimicrobial resistance genes encoded by mobile genetic elements (MGE). Here, we investigate this mobilome in successful hospital associated genetic lineages, E. faecium sequence type (ST)17 (n=10) and ...
    • An investigation of multidisciplinary complex health care interventions - steps towards an integrative treatment model in the rehabilitation of People with Multiple Sclerosis 

      Skovgaard, Lasse; Bjerre, Liv; Haahr, Niels; Paterson, Charlotte; Launsø, Laila; Boesen, Finn; Nissen, Michael; Ottesen, May-Britt; Mortensen, Christina; Olsen, Anette; Borch, Søren; Mortensen, Birte K.; Rasmussen, Gudrun A.; Sietam, Kirsten; Staalkjær, Frank; Pedersen, Karin; Søndermark, Kirsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      The Danish Multiple Sclerosis Society initiated a large-scale bridge building and integrative treatment project to take place from 2004–2010 at a specialized Multiple Sclerosis (MS) hospital. In this project, a team of five conventional health care practitioners and five alternative practitioners was set up to work together in developing and offering individualized treatments to 200 people with MS. ...
    • Ionizing radiation abrogates the pro-tumorigenic capacity of cancer-associated fibroblasts co-implanted in xenografts 

      Grinde, Maria Tunset; Vik, Jørg; Camilio, Ketil Andre; Martinez-Zubiaurre, Inigo; Hellevik, Turid (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-25)
      Cancer-associated fibroblasts (CAFs) are abundantly present in solid tumors and affect tumorigenesis and therapeutic responses. In the context of clinical radiotherapy, the impact of irradiated CAFs to treatment outcomes is largely unexplored. Aiming at improving radiotherapy efficacy, we have here explored the effect of radiation on the inherent pro-tumorigenic capacity of CAFs in animals. Ionizing ...
    • Is a high level of general practitioner consultations associated with low outpatients specialist clinic use? A cross-sectional study 

      Deraas, Trygve Sigvart; Berntsen, Gro; Hasvold, Toralf; Ringberg, Unni; Førde, Olav Helge (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Objective: To examine if increased general practice activity is associated with lower outpatient specialist clinic use. Design: Cross-sectional population based study. Setting: All 430 Norwegian municipalities in 2009. Participants: All Norwegians aged ≥65 years (n=721 915; 56% women—15% of the total population). Main outcome measure: Specialised care outpatient clinic consultations per 1000 ...
    • Isolated perfused working hearts provide valuable additional information during phenotypic assessment of the diabetic mouse heart 

      Pedersen, Tina Myhre; Boardman, Neoma; Hafstad, Anne Dragøy; Aasum, Ellen (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-01)
      Although murine models for studying the development of cardiac dysfunction in diabetes mellitus are well established, their reported cardiac phenotypes vary. These reported divergences may, in addition to the severity of different models, also be linked to the methods used for cardiac functional assessment. In the present study, we examined the functional changes using conventional transthoracic ...
    • Ixodes ricinus and Borrelia prevalence at the Arctic Circle in Norway 

      Hvidsten, Dag; Stuen, Snorre; Jenkins, Andrew; Dienus, Olaf; Olsen, Renate Slind; Kristiansen, Bjørn-Erik; Mehl, Reidar Arne; Matussek, Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2013-11-18)
      The distribution limit of Ixodes ricinus ticks in northwestern Europe (Brønnøy, Norway, 1◦ south of the Arctic Circle), has been known since the 1930s. To reconfirm this finding and extend studies in the areas adjacent to the Arctic Circle (66◦33 N), ticks were collected from dogs and cats in 8 districts in northern Norway from 64◦56 N to 68◦48 N. We detected 549 I. ricinus, 244 (44%) of them ...
    • Iyengar Yoga for Distressed Women: A 3-Armed Randomized Controlled Trial 

      Michalsen, Andreas; Jeitler, Michael; Brunnhuber, Stefan; Lüdtke, Rainer; Büssing, Arndt; Musial, Frauke; Dobos, Gustav; Kessler, Christian (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Distress is an increasing public health problem. We aimed to investigate the effects of an Iyengar yoga program on perceived stress and psychological outcomes in distressed women and evaluated a potential dose-effect relationship. Seventy-two female distressed subjects were included into a 3-armed randomized controlled trial and allocated to yoga group 1 (n = 24) with twelve 90 min sessions over 3 ...