Blar i tittel Artikler, rapporter og annet (medisinsk biologi)

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    • A Phylogenetic Study of SPBP and RAI1: Evolutionary Conservation of Chromatin Binding Modules 

      Darvekar, Sagar; Rekdal, Cecilie; Johansen, Terje; Sjøttem, Eva (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Our genome is assembled into and array of highly dynamic nucleosome structures allowing spatial and temporal access to DNA. The nucleosomes are subject to a wide array of post-translational modifications, altering the DNAhistone interaction and serving as docking sites for proteins exhibiting effector or “reader” modules. The nuclear proteins SPBP and RAI1 are composed of several putative “reader” ...

    • Physical activity and bone : the importance of the various mechanical stimuli for bone mineral density : a review 

      Morseth, Bente; Emaus, Nina; Jørgensen, Lone (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Numerous studies have reported benefits of regular physical activity on bone mineral density (BMD). The effects of physical activity on BMD are primarily linked to the mechanisms of mechanical loading, but the understanding of the precise mechanism behind the association is incomplete. The aim of this paper was to review the main findings concerning sources and types of mechanical stimuli in relation ...

    • Physical activity and cardiovascular risk factors in a 40- to 42-year-old rural Norwegian population from 1975–2010: repeated cross-sectional surveys 

      Solbraa, Ane; Holme, Ingar Morten K; Graff-Iversen, Sidsel; Resaland, Geir Kåre; Aadland, Eivind; Anderssen, Sigmund Alfred (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
      Background: Geographical differences in cardiovascular diseases (CVD) have been observed among Norwegian counties. Better long-term health status and higher physical activity (PA) levels have been documented in the county of Sogn & Fjordane compared with other counties. However, recent trends in CVD risk factors have not been documented. The aim of this study was to investigate the secular trends ...

    • Physical activity and mortality among Norwegian women : the Norwegian Women and Cancer Study 

      Borch, Kristin Benjaminsen; Braaten, Tonje; Lund, Eiliv; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Physical activity (PA) and its relationship with all-cause mortality suggest a strong and consistent inverse association. This study prospectively investigated the association between PA level and mortality among participants of the Norwegian Women and Cancer (NOWAC) Study. A total of 66,136 NOWAC participants were followed-up until December 31st 2008. PA level and possible confounding factors ...

    • Physical activity and the risk of postmenopausal breast cancer - The Norwegian Women and Cancer Study 

      Borch, Kristin Benjaminsen; Lund, Eiliv; Braaten, Tonje; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Physicians' messages in problematic sickness certification : a narrative analysis of case reports 

      Engblom, Monika; Alexanderson, Kristina; Rudebeck, Carl Edvard (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Many physicians find sickness certification tasks problematic. There is some knowledge about situations that are experienced as problematic, whereas less is understood about how physicians respond to the problems they face. One way to acquire such knowledge is to consider “reflection-in-action”, aspects of which are expressed in the physician’s interpretation of the patient’s story. The aim of this ...

    • Plasma Fatty Acid Ratios Affect Blood Gene Expression Profiles - A Cross-Sectional Study of the Norwegian Women and Cancer Post-Genome Cohort 

      Olsen, Karina Standahl; Fenton, Christopher Graham; Frøyland, Livar; Waaseth, Marit; Paulssen, Ruth H; Lund, Eiliv (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      High blood concentrations of n-6 fatty acids (FAs) relative to n-3 FAs may lead to a “physiological switch” towards permanent low-grade inflammation, potentially influencing the onset of cardiovascular and inflammatory diseases, as well as cancer. To explore the potential effects of FA ratios prior to disease onset, we measured blood gene expression profiles and plasma FA ratios (linoleic ...

    • Plasma levels of apolipoprotein-E in residents of the European North of Russia 

      Kaneva, Anastasiya M.; Bojko, Evgeny; Potolitsyna, Natalya N.; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Apolipoprotein-E (apoE) is one of the metabolically active apoproteins and plays an important role in lipid metabolism. However, there are no data on levels of apoE in residents of the North in spite of the fact that specific features of lipid metabolism in the northerners are described. The present work was designed to study plasma levels of apoE in residents of the European North ...

    • Plasma methionine, choline, betaine, and dimethylglycine in relation to colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

      Nitter, Mathilde Hjelle; Norgård, Benedicte Wentzel; De Vogel, Stefan; Eussen, Simone; Meyer, Klaus; Ulvik, Arve; Ueland, Per Magne; Nygård, Ottar; Vollset, Stein Emil; Bjørge, Tone; Tjønneland, Anne; Hansen, Louise; Boutron-Ruault, Marie-Christine; Racine, Antoine; Cottet, Vanessa; Kaaks, Rudolf; Kühn, Tilman; Trichopoulou, Antonia; Bamia, Christina; Naska, Androniki; Grioni, Sara; Palli, Domenico; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Bueno-de-Mesquita, H. Bas; Van Kranen, Henk J.; Peeters, Petra H. M.; Weiderpass, Elisabete; Dorronsoro, Miren; Jakszyn, Paula; Sánchez, María-José; Argüelles, Marcial Vicente; Huerta, José-Maria; Barricarte, Aurelio; Johansson, Matthias; Ljuslinder, Ingrid; Khaw, Kay Tee; Wareham, Nicholas J.; Freisling, Heinz; Duarte-Salles, Talita; Stepien, Magdalena; Gunter, Mark J.; Riboli, Élio B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Plasma microRNAs as biomarkers of pancreatic cancer risk in a prospective cohort study 

      Duell, Eric J.; Lujan-Barroso, Leila; Sala, Núria; Deitz McElyea, Samantha; Overvad, Kim; Tjønneland, Anne; Olsen, Anja; Weiderpass, Elisabete; Busund, Lill-Tove; Moi, Line; Muller, David; Aune, Dagfinn; Naccarati, Alessio; Panico, Salavatore; Tagliabue, Giovanna; Tumino, Rosario; Palli, Domenico; Kaaks, Rudolf; Katzke, Verena A.; Boeing, Heiner; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Trichopoulou, Antonia; Lagiou, Pagona; Kotanidou, Anastasia; Travis, Ruth C.; Wareham, Nick; Khaw, Kay-Tee; Quirõs, Jose Ramõn; Rodríguez-Barranco, Miguel; Dorronsoro, Miren; Chirlaque, María Dolores; Ardanaz, Eva; Severi, Gianluca; Boutron-Ruault, Marie-Christine; Rebours, Vinciane; Brennan, Paul; Gunter, Marc; Scelo, Ghislaine; Cote, Greg; Sherman, Stuart; Korc, Murray (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-12)
      Noninvasive biomarkers for early pancreatic ductal adenocarcinoma (PDAC) diagnosis and disease risk stratification are greatly needed. We conducted a nested case-control study within the Prospective Investigation into Cancer and Nutrition (EPIC) cohort to evaluate prediagnostic microRNAs (miRs) as biomarkers of subsequent PDAC risk. A panel of eight miRs (miR-10a, -10b, -21-3p, -21-5p, -30c, -106b, ...

    • Plasma profile of microRNA after supplementation with high doses of vitamin D3 for 12 months 

      Jorde, Rolf; Svartberg, Johan; Joakimsen, Ragnar Martin; Coucheron, Dag-Hugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2012-05-17)
      Background: Recently a large number of short non-coding-RNAs (microRNAs, (miRNA)) have been identified. These miRNAs act as post-transcriptional regulators where they generally have an inhibitory function. miRNAs are present in all human cells, and they are also detected in serum or plasma. The miRNAs have a broad range of actions, and their biogenesis must therefore be under tight control. One ...

    • Platelet alloimmunization is associated with low grade chronic histiocytic intervillositis - A new link to a rare placental lesion? 

      Nedberg, Nora Hersoug; Turowski, Gitta Erika; Guz, Katarzyna; Przytuła, Ewa; Uhrynowska, Małgorzata; Roald, Borghild; Husebekk, Anne; Sitras, Vasilis; Nystad, Mona; Dębska, Marzena; Brojer, Ewa; Tiller, Heidi (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-23)
      <i>Introduction</i> - Maternal alloimmunization against human platelet antigen (HPA)-1a has been implied to mediate both reduced birth weight and chronic placental inflammation. Fetal growth restriction is associated with different types of chronic inflammation in the placenta, mainly chronic histiocytic intervillositis and chronic villitis. The aim of this prospective study was to do a systematic ...

    • Political Manipulation in Human Rights Violations: A Case of Honor Killings in Balochistan, Pakistan 

      Khalil, Noor Akbar; Sheikh, Mashhood Ahmed (Journal article; Tidsskriftartikkel, 2010)

    • Polyphyletic origin of the genus Physarum (Physarales, Myxomycetes) revealed by nuclear rDNA mini-chromosomal analysis and group I intron synapomorphy 

      Nandipati, Satish C R; Haugli, Kari B.; Coucheron, Dag-Hugo; Haskins, Edward F.; Johansen, Steinar (Journal article; Tidsskriftartikkel; Peer reviewed, 2012-08-31)
      Physarales represents the largest taxonomic order among the plasmodial slime molds (myxomycetes). Physarales is of particular interest since the two best-studied myxomycete species, Physarum polycephalum and Didymium iridis, belong to this order and are currently subjected to whole genome and transcriptome analyses. Here we report molecular phylogeny based on ribosomal DNA (rDNA) sequences that ...

    • The population structure of vancomycin-resistant and -susceptible Enterococcus faecium in a low-prevalence antimicrobial resistance setting is highly influenced by circulating global hospital-associated clones 

      al Rubaye, Mushtaq Talib Shawi; Janice, Jessin; Bjørnholt, Jørgen; Kacelnik, Oliver; Haldorsen, Bjørg C; Nygaard, Randi Monsen; Hegstad, Joachim; Sundsfjord, Arnfinn Ståle; Hegstad, Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-19)
      Between 2010 and 2015 the incidence of vancomycin-resistant Enterococcus faecium (VREfm) in Norway increased dramatically. Hence, we selected (1) a random subset of vancomycin-resistant enterococci (VRE) from the Norwegian Surveillance System for Communicable Diseases (2010–15; n=239) and (2) Norwegian vancomycin-susceptible E. faecium (VSEfm) bacteraemia isolates from the national surveillance ...

    • A population-based study on health and living conditions in areas with mixed Sami and Norwegian settlements - The SAMINOR 2 questionnaire study 

      Brustad, Magritt; Hansen, Ketil Lenert; Broderstad, Ann Ragnhild; Hansen, Solrunn; Melhus, Marita (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Post-test adverse psychological effects and coping mechanisms amongst HIV self-tested individuals living in couples in urban Blantyre, Malawi 

      Kumwenda, Moses Kelly; Corbett, Elizabeth Lucy; Choko, Augustine Talumba; Chikovore, Jeremiah; Kaswaswa, Kruger; Mwapasa, Mphatso; Sambakunsi, Rodrick; Gutteberg, Tore Jarl; Gordon, Stephen; Munthali, Alister; Desmond, Nicola (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-12)
      <i>Introduction</i> - Mandatory face-to-face counselling is necessary during HIV testing but difficult to implement within the context of HIV self-testing. We investigated adverse psychological effects and coping mechanisms following HIV-positive and HIV-discordant test results amongst self-tested individuals living in couples in urban Blantyre, Malawi.<p> <p><i>Methods</i> - Qualitative data ...

    • Practical health co-operation-the impact of a referral template on quality of care and health care co-operation: study protocol for a cluster randomized controlled trial 

      Wåhlberg, Henrik; Valle, Per Christian; Malm, Siri; Broderstad, Ann Ragnhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: The referral letter plays a key role both in the communication between primary and secondary care, and in the quality of the health care process. Many studies have attempted to evaluate and improve the quality of these referral letters, but few have assessed the impact of their quality on the health care delivered to each patient. Methods: A cluster randomized trial, with the general ...

    • Praksisstudienes omfang og organisering i bioingeniørutdanningen 

      Furuseth, May-Tove; Kvissel, Anne Katrine; Berg, Vivian; Kjøbli, Eli; Volden, Vivi; Solli, Ann Iren; Granerud, Beathe Kiland; Lie-Jensen, Anette Christensen; Nygård, Irene; Alm, Bente; Ersvær, Elisabeth; Sjøholt, Gry (Journal article; Tidsskriftartikkel; Peer reviewed, 2022)
      Siden 2005 har omfang og innhold i bioingeniørutdanningen vært definert av en nasjonal rammeplan for å sikre likeverdig sluttkompetanse for alle kandidater. Fra 2019 ble en ny forskrift om nasjonale retningslinjer fastsatt. Både tidligere rammeplan og nye retningslinjer har regulert læringsutbyttene og omfang av praksis i utdanningen. I denne studien kartlegges omfang og organisering av praksisstudiene ...

    • Pre- and post-diagnostic blood profiles of chlorinated persistent organic pollutants and metabolic markers in type 2 diabetes mellitus cases and controls; a pilot study 

      Berg, Vivian; Charles, Dolley; Bergdahl, Ingvar A.; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Tornevi, Andreas; Huber, Sandra; Fuskevåg, Ole Martin; Rylander, Charlotta (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-09)
      Objective - Several risk factors for type 2 diabetes mellitus (T2DM) are also associated with blood concentrations of persistent organic pollutants (POPs), and factors related to the disease may affect POP concentrations, and subsequent associations between POPs and T2DM. The purpose of this pilot study was to investigate the change in concentrations of lipids, hormones and POPs pre- and post-diagnosis ...