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  Visible light-mediated alkyl radical additions to alkenyl and alkynyl silanes 

  Baussière, Floriane (Doctoral thesis; Doktorgradsavhandling, 2024-11-15)

  <p>Radicals are reactive species that possess a unique reactivity, which enables them to form unusual bonds unreachable by ionic chemistry. In the last twenty years, radical chemistry has benefited from a renewed interest due to the emergence of methods that can initiate radical reactions under mild conditions. Among those, visible light-mediated radical chemistry has become established as a powerful ...
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  Frailty and health-related life quality in long-term follow up of intensive care patients above 65 years old: Protocol for a Norwegian prospective, observational multicenter study 

  Kroken, Bjørn Anders; Bergum, Daniel; Berg, K.S.; Espinasse, Marina; Fossum, Ole Kristian; Garratt, Andrew; Klepstad, Pål; Kvåle, Reidar; Strand, Bjørn Heine; Flaatten, Hans Kristian; K Frisvold, Shirin (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-10-01)

  Background - Frailty is strongly correlated with mortality in intensive care unit patients, yet routine screening among intensive care patients is rarely performed.<p> <p>The aim of this study is to assess frailty and health-related quality of life (HRQoL) in patients before intensive care admission and to compare this with outcomes after 3 and 12-months. The Clinical Frailty Scale and EQ-5D-5L ...
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  Aquaporin-4 deletion leads to reduced infarct volume and increased peri-infarct astrocyte reactivity in a mouse model of cortical stroke 

  Skauli, Nadia; Zohoorian Izadpanah, Negar; Banitalebi, Shervin; Geiseler, Samuel Jakob; Salameh, Maher; Shreyas, Rao; Morland, Cecilie; Ottersen, Ole Petter; Amiry-Moghaddam, Mahmood (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-24)

  Aquaporin-4 (AQP4) is the main water channel in brain and is enriched in perivascular astrocyte processes abutting brain microvessels. There is a rich literature on the role of AQP4 in experimental stroke. While its role in oedema formation following middle cerebral artery occlusion (MCAO) has been studied extensively, its specific impact on infarct volume remains unclear. This study investigated ...
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  Modeling Radiologists’ Assessments to Explore Pairing Strategies for Optimized Double Reading of Screening Mammograms 

  Gommers, Jessie J. J.; Abbey, Craig K.; Strand, Fredrik; Taylor-Phillips, Sian; Jenkinson, David J.; Larsen, Marthe; Hofvind, Solveig Sand-Hanssen; Broeders, Mireille J. M.; Sechopoulos, Ioannis (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-07-30)

  Purpose - To develop a model that simulates radiologist assessments and use it to explore whether pairing readers based on their individual performance characteristics could optimize screening performance.<p> <p>Methods - Logistic regression models were designed and used to model individual radiologist assessments. For model evaluation, model-predicted individual performance metrics and paired ...
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  The Reindeer Circadian Clock Is Rhythmic and Temperature-compensated But Shows Evidence of Weak Coupling Between the Secondary and Core Molecular Clock Loops 

  Appenroth, Daniel; Ravuri, Chandra Sekhar; Torppa, Sara K.; Wood, Shona Hiedi; Hazlerigg, David Grey; West, Alexander Christopher (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-10-06)

  Circadian rhythms synchronize the internal physiology of animals allowing them to anticipate daily changes in their environment. Arctic habitats may diminish the selective advantages of circadian rhythmicity by relaxing daily rhythmic environmental constraints, presenting a valuable opportunity to study the evolution of circadian rhythms. In reindeer, circadian control of locomotor activity and ...

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