• Gut microbiota-dependent trimethylamine N-oxide associates with inflammation in common variable immunodeficiency 

    Macpherson, Magnhild Eide; Hov, Johannes Espolin Roksund; Ueland, Thor; Dahl, Tuva Børresdatter; Kummen, Martin; Otterdal, Kari; Holm, Kristian; Berge, Rolf Kristian; Mollnes, Tom Eirik; Trøseid, Marius; Halvorsen, Bente; Aukrust, Pål; Fevang, Børre; Jørgensen, Silje Fjellgård (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-16)
    A substantial proportion of patients with common variable immunodeficiency (CVID) have inflammatory and autoimmune complications of unknown etiology. We have previously shown that systemic inflammation in CVID correlates with their gut microbial dysbiosis. The gut microbiota dependent metabolite trimethylamine N-oxide (TMAO) has been linked to several metabolic and inflammatory disorders, but has ...
  • Simulating crude oil exposure, uptake and effects in North Atlantic Calanus finmarchicus populations 

    Broch, Ole Jacob; Nepstad, Raymond; Ellingsen, Ingrid H.; Bast, Radovan; Skeie, Morten; Carroll, JoLynn (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-08)
    A simulation model framework (SYMBIOSES) that includes a 3-dimensional ocean physics and biology model and a model for transport and fate of oil was used to investigate the potential for bioaccumulation and lethal/sublethal effects of oil components in the copepod <i>Calanus finmarchicus</i> in the Lofoten-Vesterålen archipelago of Norway. The oil model is coupled with the biology model by way of a ...
  • Learning communities and co-creative tourism practices in NGDO projects 

    Bertella, Giovanna; Rinaldi, Maria Donata (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-16)
    In this study, we considered tourism collaboration for sustainable development as a co-creative practice of learning about tourism in order to achieve benefits for local communities. We focused on projects run by non-governmental development organisations (NGDOs) and the challenges relating to their long-term impact. These challenges concern the projects’ potential to facilitate the emergence and/or ...
  • Perfluoroalkyl acids potentiate glutamate excitotoxicity in rat cerebellar granule neurons 

    Berntsen, Hanne Friis; Moldes-Anaya, Angel; Bjørklund, Cesilie Granum; Ragazzi, Lorenzo; Haug, Trude M; Strandabø, Rønnaug; Verhaegen, Steven; Paulsen, Ragnhild Elisabeth; Ropstad, Erik; Tasker, Andrew (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-04)
    Perfluoroalkyl acids (PFAAs) are persistent man-made chemicals, ubiquitous in nature and present in human samples. Although restrictions are being introduced, they are still used in industrial processes as well as in consumer products. PFAAs cross the blood-brain-barrier and have been observed to induce adverse neurobehavioural effects in humans and animals as well as adverse effects in neuronal in ...
  • Performance differences between nations exploiting a common natural resource: The Icelandic–Norwegian mackerel case 

    Bertheussen, Bernt Arne; Dreyer, Bent; Dreyer, Sofie; Evenseth, Susann (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-25)
    The same type of industries, located in different nations, may perform differently in global markets. This comparative case study of the Icelandic and Norwegian mackerel industries explores whether national resources, capabilities, and institutional environments can help elucidate performance differences in exporting a common natural resource. To gain insight into the phenomenon, the present study ...

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