• Drug resistance and the functional role of microRNAs in neuroblastoma 

    Bhavsar, Swapnil Parashram (Doctoral thesis; Doktorgradsavhandling, 2019-06-13)
    Neuroblastoma is the most common solid tumor in infants. Most of the children diagnosed above one year of age, shows metastatic disease and poor prognosis. Chemotherapy is one of the principle mode of treatment. However, resistance to drug represent a major clinical obstacle for the effective treatment of cancer. MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression, ...
  • Bruk av kosttilskudd blant pasienter over 70 år ved Nordlandssykehuset i Bodø 

    Ramstad, Elise Sørensen (Master thesis; Mastergradsoppgave, 2019-05-14)
    Bruk av kosttilskudd er vanlig i den generelle befolkningen. Kosttilskudd er ikke underlagt de samme lover og reguleringer som legemidler, og det er kjent at kosttilskudd kan gi bivirkninger og interagere med legemidler. Eldre mennesker er en spesielt utsatt gruppe for bivirkninger og interaksjoner. Formålet med studien er å kartlegge bruk av kosttilskudd blant pasienter over 70 år, undersøke om ...
  • Isolation and Characterisation of Halogenated and Bioactive Compounds from Thalassospira sp. and Alteromonas sp. 

    Ali, Nadia Ghazi (Master thesis; Mastergradsoppgave, 2019-05-15)
    Bacterial natural products have contributed with a large part of the bioactive compounds that lead to drugs, and the biggest portion of the marketed antibiotics are bacterial products or their derivatives. Marine bacteria are not yet investigated to the same extend as their terrestrial counterparts. Therefore, they are considered a promising source for novel bioactive metabolites for drug development, ...
  • Differential invariants of Lie pseudogroups 

    Schneider, Eivind (Doctoral thesis; Doktorgradsavhandling, 2019-05-10)
    We compute differential invariants for several Lie pseudogroups, and use them for solving the equivalence and classification problem for a variety of mathematical structures appearing in geometry and mathematical physics. We demonstrate utility of the algebra of rational scalar differential invariants for solving these two problems, also in cases where the structures are given as solutions to a ...
  • Modulation of dendritic cells phenotype and functions by irradiated and non-irradiated lung cancer fibroblasts. An in vitro study. 

    Tornaas, Stian (Master thesis; Mastergradsoppgave, 2019-05-15)
    Stromal cells in the tumor microenvironment (TME) interacts with cancer cells and affect their behavior in diverse manners. In this study, we investigated in vitro the mechanisms by which non-irradiated and irradiated cancer-associated fibroblasts (CAFs) isolated from patients with non-small cell lung carcinoma (NSCLC) affected the phenotype and function of monocyte-derived dendritic cells (Mo-DCs) ...

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