• Sex and Age-Group Differences in Strength, Jump, Speed, Flexibility, and Endurance Performances of Swedish Elite Gymnasts Competing in TeamGym 

    Höög, Stefan; Andersson, Erik P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-13)
    <i>Purpose</i>: To analyze sex and age group differences in strength, jump, speed, flexibility, and endurance performances of TeamGym athletes.<br><br> <i>Methods</i>: A total of 91 Swedish elite gymnasts (junior female, <i>n</i> = 26, age = 15.4 y; senior female, <i>n</i> = 23, age = 20.0 y; junior male, <i>n</i> = 19, age = 15.6 y; senior male, <i>n</i> = 23, age = 20.6 y) participated in three ...
  • Detection of phenotype-specific therapeutic vulnerabilities in breast cells using a CRISPR loss-of-function screen 

    Barkovskaya, Anna; Goodwin, Craig; Seip, Kotryna; Hilmarsdòttir, Bylgja; Pettersen, Solveig; Stalnecker, Clint; Engebraaten, Olav; Briem, Eirikur; Der, Channing J; Moestue, Siver Andreas; Guðjónsson, Þórarinn; Mælandsmo, Gunhild Mari; Prasmickaite, Lina (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-24)
    Cellular phenotype plasticity between the epithelial and mesenchymal states has been linked to metastasis and heterogeneous responses to cancer therapy, and remains a challenge for the treatment of triple-negative breast cancer (TNBC). Here, we used isogenic human breast epithelial cell lines, D492 and D492M, representing the epithelial and mesenchymal phenotypes, respectively. We employed a CRISPR-Cas9 ...
  • Identifying the drivers of multidrug-resistant Klebsiella pneumoniae at a European level 

    Kachalov, Viacheslav N.; Nguyen, Huyen; Balakrishna, Suraj; Salazar-Vizcaya, Luisa; Sommerstein, Rami; Kuster, Stefan P.; Hauser, Anthony; Abel-Zur Wiesch Genannt Hülsho, Pia Karoline; Klein, E; Kouyos, Roger D. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-29)
    Beta-lactam- and in particular carbapenem-resistant Enterobacteriaceae represent a major public health threat. Despite strong variation of resistance across geographical settings, there is limited understanding of the underlying drivers. To assess these drivers, we developed a transmission model of cephalosporin- and carbapenem-resistant <i>Klebsiella pneumoniae</i>. The model is parameterized using ...
  • Transcranial Direct Current Stimulation above the Medial Prefrontal Cortex Facilitates Decision-Making following Periods of Low Outcome Controllability 

    Csifcsak, Gabor; Bjørkøy, Jorunn; Kuyateh, Sarjo; Reithe, Haakon; Mittner, Matthias (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-25)
    Recent studies suggest that choice behavior in reinforcement learning tasks is shaped by the level of outcome controllability. In particular, Pavlovian bias (PB) seems to be enhanced under low levels of control, manifesting in approach tendencies toward rewards and response inhibition when facing potential losses. The medial prefrontal cortex (mPFC) has been implicated both in evaluating outcome ...
  • Bilinguals are better than monolinguals in detecting manipulative discourse 

    Leivada, Evelina; Mitrofanova, Natalia; Westergaard, Marit (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-07)
    One of the most contentious topics in cognitive science concerns the impact of bilingualism on cognitive functions and neural resources. Research on executive functions has shown that bilinguals often perform better than monolinguals in tasks that require monitoring and inhibiting automatic responses. The robustness of this effect is a matter of an ongoing debate, with both sides approaching bilingual ...

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