Recent additions

  • Risk of cervical intraepithelial neoplasia grade 3 or higher (CIN3+) among women with HPV-test in 1990–1992, a 30-year follow-up study 

    Riibe, Marit Østlyngen; Sørbye, Sveinung Wergeland; Simonsen, Gunnar Skov; Sundsfjord, Arnfinn; Ekgren, Josef; Maltau, Jan Martin (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-22)
    <i>Background/objective</i> - Having a 30-year follow-up of a cohort of women tested for HPV is a unique opportunity to further study long-term risk of CIN3+. The study objective was to compare HPV status at baseline with the risk of CIN3+ in the follow-up period of 30 years.<br><br> <i>Methods</i> - All women (n = 642) referred to the HPV outpatient clinic at the University Hospital of North ...
  • Ginseng for Erectile Dysfunction: A Cochrane Systematic Review 

    Lee, Hye Won; Lee, Myeong Soo; Kim, Tae-Hun; Alræk, Terje; Zaslawski, Chris; Kim, Jong Wook; Moon, Du Geon (Journal article; Tidsskriftartikkel; Peer reviewed, 2021)
    The objectives of this study were to assess the effects of ginseng on erectile dysfunction. We searched multiple electronic databases from their inceptions to 30 January 2021 without restrictions by language. We included randomized or quasirandomized controlled trials that evaluated the use of any type of ginseng as a treatment for erectile dysfunction compared to placebo or conventional treatment. ...
  • Development of 8f-labeled radiotracers for pet imaging of the adenosine a2a receptor: Synthesis, radiolabeling and preliminary biological evaluation 

    Lai, Thu Hang; Schröder, Susann; Toussaint, Magali; Dukić-Stefanović, Sladjana; Kranz, Mathias; Ludwig, Friedrich-Alexander; Fischer, Steffen; Steinbach, Jörg; Deuther-Conrad, Winnie; Brust, Peter; Moldovan, Rareş-Petru (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-25)
    The adenosine A<sub>2A</sub> receptor (A<sub>2A</sub>R) represents a potential therapeutic target for neurodegenerative diseases. Aiming at the development of a positron emission tomography (PET) radiotracer to monitor changes of receptor density and/or occupancy during the A<sub>2A</sub>R-tailored therapy, we designed a library of fluorinated analogs based on a recently published lead compound ...
  • Validity and responsiveness of EQ-5D-5L and SF-6D in patients with health complaints attributed to their amalgam fillings: a prospective cohort study of patients undergoing amalgam removal 

    Lamu, Admassu N.; Björkman, Lars; Hamre, Harald Johan; Alræk, Terje; Musial, Frauke; Robberstad, Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-17)
    <i>Background</i> - Evidence of health utility changes in patients who suffer from longstanding health complaints attributed to dental amalgam fillings are limited. The change in health utility outcomes enables calculating quality-adjusted life-year (QALY) and facilitates the comparison with other health conditions. The purpose of this study was to estimate the validity and responsiveness of the ...
  • Agenda navigation in consultations covering multiple topics. A qualitative case study from general practice 

    Guassora, Ann Dorrit; Johansen, May-Lill; Malterud, Kirsti (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-26)
    Objective - To explore how agenda navigation may be accomplished underway in consultations covering multiple topics, we identified and analyzed one GP’s communicative strategies.<p> <p>Design, setting, and subjects - A qualitative observational case study with linguistic microanalysis of an exemplary consultation between a female patient with diabetes and her male GP. We used speech act theory ...
  • The prognostic effect of KRAS mutations in non-small cell lung carcinoma revisited: A norwegian multicentre study 

    Wahl, Sissel Gyrid Freim; Hong, Yan Dai; Emdal, Elisabeth Fritzke; Berg, Thomas; Halvorsen, Tarje Onsøien; Ottestad, Anine Larsen; Lund-Iversen, Marius; Brustugun, Odd; Førde, Dagny; Paulsen, Erna-Elise; Donnem, Tom; Andersen, Sigve; Grønberg, Bjørn Henning; Richardsen, Elin (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-26)
    Background: due to emerging therapeutics targeting KRAS G12C and previous reports with conflicting results regarding the prognostic impact of KRAS and KRAS G12C in non-small cell lung cancer (NSCLC), we aimed to investigate the frequency of KRAS mutations and their associations with clinical characteristics and outcome. Since mutation subtypes have different preferences for downstream pathways, we ...
  • Dental caries in children and adolescents with juvenile idiopathic arthritis and controls: a multilevel analysis 

    Gil, Elisabeth G.; Åstrøm, Anne-Kristine N; Lie, Stein Atle; Rygg, Marite; Fischer, Johannes; Rosén, Annika; Bletsa, Athanasia; Luukko, Keijo; Shi, Xie-Qi; Halbig, Josefine; Frid, Paula; Cetrelli, Lena Elisabet; Tylleskär, Karin; Rosendahl, Karen; Skeie, Marit Slåttelid (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-25)
    Background - Optimal utilization of dental caries data is crucial in epidemiological research of individuals with juvenile idiopathic arthritis (JIA). The aims were to: explore whether caries is more prevalent among children and adolescents with JIA compared to controls; examine presence of caries according to JIA group, socio-behavioral and intraoral characteristics, and the extent to which ...
  • Exploring Klebsiella pneumoniae in Healthy Poultry Reveals High Genetic Diversity, Good Biofilm-Forming Abilities and Higher Prevalence in Turkeys Than Broilers 

    Franklin-Alming, Fiona; Kaspersen, Håkon; Hetland, Marit A. K.; Bakksjø, Ragna-Johanne; Nesse, Live L.; Leangapichart, Thongpan; Löhr, Iren Høyland; Telke, Amar; Sunde, Marianne (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-07)
    Klebsiella pneumoniae is a well-studied human pathogen for which antimicrobial resistant and hypervirulent clones have emerged globally. K. pneumoniae is also present in a variety of environmental niches, but currently there is a lack of knowledge on the occurrence and characteristics of K. pneumoniae from non-human sources. Certain environmental niches, e.g., animals, may be associated with high ...
  • Reciprocal transactivation of Merkel cell polyomavirus and high-risk human papillomavirus promoter activities and increased expression of their oncoproteins 

    Rasheed, Kashif; Sveinbjørnsson, Baldur; Moens, Ugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-03)
    <i>Background</i> - Approximately 15% of human cancers are attributed to viruses. Numerous studies have shown that high-risk human polyomaviruses (HR-HPV) and Merkel cell polyomavirus (MCPyV) are two human tumor viruses associated with anogenetal and oropharyngeal cancers, and with Merkel cell carcinoma, respectively. MCPyV has been found in HR-HPV positive anogenetal and oropharyngeal tumors, ...
  • Identifying Resilience Factors of Distress and Paranoia During the COVID-19 Outbreak in Five Countries 

    Mækelæ, Martin Jensen; Reggev, Niv; Defelipe, Renata P.; Dutra, Natalia; Tamayo, Ricardo; Klevjer, Kristoffer; Pfuhl, Gerit (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-10)
    The ongoing COVID-19 pandemic outbreak has affected all countries with more than 100 million confirmed cases and over 2.1 million casualties by the end of January 2021 worldwide. A prolonged pandemic can harm global levels of optimism, regularity, and sense of meaning and belonging, yielding adverse effects on individuals' mental health as represented by worry, paranoia, and distress. Here we studied ...
  • Parent reports of children's emotional and behavioral problems in a low- and middleincome country (LMIC): An epidemiological study of Nepali schoolchildren 

    Ma, Jasmine; Mahat, Pashupati; Brøndbo, Per Håkan; Handegård, Bjørn H.; Kvernmo, Siv; Javo, Anne Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-03)
    <i>Background</i> - As epidemiological data on child mental health in low- and middle-income countries are limited, a large-scale survey was undertaken to estimate the prevalence and amount of child emotional and behavioral problems (EBP) in Nepal as reported by the parents.<br><br> <i>Methods</i> - 3820 schoolchildren aged 6–18 years were selected from 16 districts of the three geographical ...
  • Religion and Health in Arctic Norway–the association of religious and spiritual factors with suicidal behaviour in a mixed Sámi and Norwegian adult population - The SAMINOR 2 Questionnaire Survey 

    Kiærbech, Henrik; Silviken, Anne; Lorem, Geir F; Kristiansen, Roald E; Spein, Anna Rita (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-12)
    Given the higher suicide rates among the adult population in the northernmost part of Norway and some unfavourable psychosocial outcomes associated with the Laestadian revival movement in this region, it is reasonable to investigate the relationship between religiosity/spirituality and suicidal behaviour in this context. This study used cross-sectional data from the population-based SAMINOR 2 ...
  • Access to, use, knowledge, and preferences for information technology and technical equipment among people with chronic obstructive pulmonary disease (COPD) in Sweden. A cross-sectional survey study 

    Sönnerfors, Pernilla; Roaldsen, Kirsti Skavberg; Ståhle, Agneta; Wadell, Karin; Halvarsson, Alexandra (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-10)
    <i>Background</i> - The use of information technology can make pulmonary rehabilitation interventions in people with chronic obstructive pulmonary disease (COPD) more flexible and thereby has the potential to reach a larger proportion of the population. However, the success of using information technology in pulmonary rehabilitation is dependent on the end-user’s competence in information technology ...
  • Rewarming From Hypothermic Cardiac Arrest Applying Extracorporeal Life Support: A Systematic Review and Meta-Analysis 

    Bjertnæs, Lars J.; Hindberg, Kristian; Næsheim, Torvind; Suborov, Evgeny V.; Reierth, Eirik; Kirov, Mikhail Y.; Lebedinskii, Konstantin M.; Tveita, Torkjel (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-13)
    <i>Introduction</i>: This systematic review and meta-analysis aims at comparing outcomes of rewarming after accidental hypothermic cardiac arrest (HCA) with cardiopulmonary bypass (CPB) or/and extracorporeal membrane oxygenation (ECMO).<br><br> <i>Material and Methods</i>: Literature searches were limited to references with an abstract in English, French or German. Additionally, we searched ...
  • Metabolic syndrome, obesity and ethnicity—The SAMINOR Study 

    Michalsen, Vilde Lehne (Doctoral thesis; Doktorgradsavhandling, 2021-10-13)
    Clustering of certain cardiometabolic risk factors is known as metabolic syndrome (MetS). MetS is associated with an unhealthy lifestyle and the prevalence is increasing alongside the obesity epidemic, making it an important public health issue. Both MetS and obesity are common in the adult population in rural Northern Norway, which comprises an ethnically mixed population. MetS is defined using ...
  • Lifestyle changes among people with type 2 diabetes are associated with participation in online groups and time since diagnosis 

    Hansen, Anne Helen; Wangberg, Silje C.; Årsand, Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-12)
    <i>Background</i> - For people with Type 2 diabetes (T2D), lifestyle changes may be the most effective intervention. Online groups for people with diabetes holds a great potential to support such changes. However, little is known about the association between participation in online groups and lifestyle changes based on internet information in people with T2D. The aim of this study was to investigate ...
  • Association of High-Density Lipoprotein Cholesterol With GFR Decline in a General Nondiabetic Population 

    Melsom, Toralf; Norvik, Jon Viljar; Enoksen, Inger Therese; Stefansson, Vidar Tor Nyborg; Rismo, Renathe; Jenssen, Trond; Solbu, Marit Dahl; Eriksen, Bjørn Odvar (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-18)
    <i>Introduction</i> - Although lower high-density lipoprotein cholesterol (HDL-C) levels are considered a risk factor for cardiovascular disease (CVD), experimental evidence suggest that aging, inflammation, and oxidative stress may remodel HDL-C, leading to dysfunctional HDL-C. Population studies on HDL-C and loss of the glomerular filtration rate (GFR) reported inconsistent results, but they used ...
  • Validation of Selected Head and Neck Cancer Prognostic Markers from the Pathology Atlas in an Oral Tongue Cancer Cohort 

    Wirsing, Anna Maria; Bjerkli, Inger-Heidi; Steigen, Sonja Eriksson; Rikardsen, Oddveig G; Norvoll Magnussen, Synnøve; Hegge, Beate; Seppola, Marit; Uhlin-Hansen, Lars; Hadler-Olsen, Elin Synnøve (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-14)
    The Pathology Atlas is an open-access database that reports the prognostic value of protein-coding transcripts in 17 cancers, including head and neck cancer. However, cancers of the various head and neck anatomical sites are specific biological entities. Thus, the aim of the present study was to validate promising prognostic markers for head and neck cancer reported in the Pathology Atlas in oral ...
  • Burden, antibiotic resistance, and clonality of shigella spp. Implicated in community-acquired acute diarrhoea in Lilongwe, Malawi 

    Phiri, Abel F.N.D.; Abia, Akebe Luther King; Amoako, Daniel Gyamfi; Mkakosya, Rajab; Sundsfjord, Arnfinn; Essack, Sabiha; Simonsen, Gunnar Skov (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-28)
    Although numerous studies have investigated diarrhoea aetiology in many sub-Saharan African countries, recent data on <i>Shigella</i> species’ involvement in community-acquired acute diarrhoea (CA-AD) in Malawi are scarce. This study investigated the incidence, antibiotic susceptibility profile, genotypic characteristics, and clonal relationships of <i>Shigella flexneri</i> among 243 patients ...
  • Frafall i organisert fotball gjennom en sesong preget av COVID-19 i samfunnet – Et trenerperspektiv 

    Blomstrand, Tommy Hauge (Master thesis; Mastergradsoppgave, 2021-05-26)
    Sammendrag Introduksjon: I begynnelsen av 2020 ble samfunnet i Norge rammet av COVID-19. Dette medførte begrensninger for idretten i landet, som samfunnet generelt. Dette har medført begrenset mulighet for organisert fotball. Norges fotballforbund har rapportert om frafall på 8% i barne- og ungdomsfotballen og det fryktes større frafall i seniorfotballen. Videre tar den teoretiske rammen i denne ...

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