Recent additions

  • Evolutionary Instability of Collateral Susceptibility Networks in Ciprofloxacin-Resistant Clinical Escherichia coli Strains 

    Sørum, Vidar; Øynes, Emma Lu; Sollied Møller, Anna; Harms, Klaus; Samuelsen, Ørjan; Podnecky, Nicole L.; Johnsen, Pål Jarle (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-07)
    ABSTRACT Collateral sensitivity and resistance occur when resistance development toward one antimicrobial either potentiates or deteriorates the effect of others. Previous reports on collateral effects on susceptibility focus on newly acquired resistance determinants and propose that novel treatment guidelines informed by collateral networks may reduce the evolution, selection, and spread of ...
  • Concordance between clinical and pathology TNM-staging in lung cancer 

    Solberg, Steinar; Nilssen, Yngvar; Brustugun, Odd Terje; Haram, Per Magnus; Helland, Åslaug; Møller, Bjørn; Strand, Trond-Eirik; Wahl, Sissel Gyrid Freim; Fjellbirkeland, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-25)
    Objectives: A prerequisite for utilizing the tumour, lymph-nodes, and metastases (TNM) for the staging of lung cancer patients is a high quality of the reported data on which the staging is based. The aim of this study was to investigate the concordance between the clinical, cTNM and the pathology, pTNM staging for lung cancer, version 8 as reported to the Cancer Registry of Norway (CRN).<p> < ...
  • Antimicrobial susceptibility profiles of clinically important bacterial pathogens at the Kamuzu Central Hospital in Lilongwe, Malawi 

    Choonara, Faheema E.; Haldorsen, Bjørg; Ndhlovu, Isaac; Saulosi, Osborne; Maida, Tarsizio; Lampiao, Fanuel; Simonsen, Gunnar Skov; Essack, Sabiha Y.; Sundsfjord, Arnfinn (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-01)
    Background The aim of this prospective study was to ascertain antimicrobial resistance (AMR) in clinical bacterial pathogens from in-hospital adult patients at a tertiary hospital in Lilongwe, Malawi. Methods<p> <p>Clinical specimens (blood culture, pus, urine and cerebrospinal fluid) collected during June to December 2017 were examined for bacterial growth in standard aerobic conditions. One ...
  • Improving the Applicability of AI for Psychiatric Applications through Human-in-the-loop Methodologies 

    Chandler, Chelsea; Foltz, Peter W.; Elvevåg, Brita (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-26)
    Objectives: Machine learning (ML) and natural language processing have great potential to improve effciency and accuracy in diagnosis, treatment recommendations, predictive interventions, and scarce resource allocation within psychiatry. Researchers often conceptualize such an approach as operating in isolation without much need for human involvement, yet it remains crucial to harness human-inthe-loop ...
  • Sociodemographic factors, health indicators and lifestyle factors among participants in BreastScreen Norway 2006-2016 – a cohort profile 

    Robsahm, Trude Eid; Sagstad, Silje; Thy, Jonas Evensen; Hofvind, Solveig Sand-Hanssen (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-12)
    Purpose: To collect information on sociodemographic factors, health indicators, and lifestyle factors in women who attended the nationwide breast cancer-screening program, BreastScreen Norway, with the aim of investigating how these factors influence the risk of breast cancer, other cancer types, and cancer-related outcomes. <p>Participants: The cohort data includes self-reported responses to ...
  • Self-reported mind wandering reflects executive control and selective attention 

    Hawkins, Guy E.; Mittner, Matthias; Forstmann, Birte U.; Heathcote, Andrew (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-07)
    Mind wandering is ubiquitous in everyday life and has a pervasive and profound impact on task-related performance. A range of psychological processes have been proposed to underlie these performance-related decrements, including failures of executive control, volatile information processing, and shortcomings in selective attention to critical task-relevant stimuli. Despite progress in the development ...
  • Risk of obstetric anal sphincter injury associated with female genital mutilation/cutting and timing of deinfibulation 

    Taraldsen, Sølvi; Vangen, Siri; Øian, Pål; Sørbye, Ingvil (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-09)
    Introduction: A greater risk of obstetric anal sphincter injury has been reported among African migrants in several host countries compared with the general population. To what degree female genital mutilation/cutting affects this risk is not clear. In infibulated women, deinfibulation prevents anal sphincter injury. Whether the timing of deinfibulation affects the risk, is unknown. This study ...
  • Indigenous Sami Family Caregivers’ Experiences With Accessing and Collaborating With Municipal Health and Care Services 

    Blix, Bodil Hansen; Munkejord, Mai Camilla (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-14)
    Previous research has indicated that Indigenous Sami families in Norway use public home-based care services less often than their non-Sami peers. Based on qualitative interviews with Sami family caregivers, we explore what they experience as barriers to accessing public care services for older adults living with dementia, and how they experience collaborating with care services providers. Through a ...
  • What do I want to be? Predictors of communal occupational aspirations in early to middle childhood 

    Olsen, Marte; Olsson, Maria; Parks-Stamm, Elizabeth J.; Kvalø, Marie; Thorsteinsen, Kjærsti; Steffens, Melanie C.; Martiny, Sarah E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-07)
    Research investigating occupational aspirations in childhood is scarce. In addition, most research on occupational aspirations has focused on increasing the number of women in agentic jobs. In the present work, we investigate factors associated with communal occupational aspirations in two studies with young children (Study 1: 159 children [84 boys, 75 girls], Mage = 5.51 years, SD = 0.37; Study 2: ...
  • Mid-life alcohol consumption and survival to age 90 in men: The Tromsø Study 1979–1980 with follow-up to 2019 

    Brenn, Tormod; Løvsletten, Ola (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-25)
    Aims: The Tromsø Study 1979–1980 collected information on alcohol (beer, wine and spirits) consumption frequency and inebriation frequency, and the oldest male participants (aged 50–54 years) were followed for all-cause mortality. This study aimed to identify the impact of habitual alcohol consumption in mid-life on reaching up to 90 years of age. Results: Among the study sample of 778, a total ...
  • Guidelines on models of diabetic heart disease 

    Heather, Lisa C.; Hafstad, Anne Dragøy; Halade, Ganesh V.; Harmancey, Romain; Mellor, Kimberley M.; Mishra, Paras K.; Mulvihill, Erin E.; Nabben, Miranda; Nakamura, Michinari; Rider, Oliver J.; Ruiz, Matthieu; Wende, Adam R.; Ussher, John R. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-08)
    Diabetes is a major risk factor for cardiovascular diseases, including diabetic cardiomyopathy, atherosclerosis, myocardial infarction, and heart failure. As cardiovascular disease represents the number one cause of death in people with diabetes, there has been a major emphasis on understanding the mechanisms by which diabetes promotes cardiovascular disease, and how antidiabetic therapies impact ...
  • Metabolically Defined Body Size Phenotypes and Risk of Endometrial Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

    Kliemann, Nathalie; Ammar, Romain Ould; Biessy, Carine; Gicquiau, Audrey; Katzke, Verena; Kaaks, Rudolf; Tjønneland, Anne; Olsen, Anja; Sánchez, Maria-Jose; Crous-Bou, Marta; Pasanisi, Fabrizio; Tin, Sandar Tin; Perez-Cornago, Aurora; Aune, Dagfinn; Christakoudi, Sofia; Heath, Alicia K.; Colorado-Yohar, Sandra M.; Grioni, Sara; Skeie, Guri; Sartor, Hanna; Idahl, Annika; Rylander, Charlotta; May, Anne M.; Weiderpass, Elisabete; Freisling, Heinz; Playdon, Mary C.; Rinaldi, Sabina; Murphy, Neil; Huybrechts, Inge; Dossus, Laure; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-01)
    Background: Obesity is a risk factor for endometrial cancer but whether metabolic dysfunction is associated with endometrial cancer independent of body size is not known.<p> <p>Methods: The association of metabolically defined body size phenotypes with endometrial cancer risk was investigated in a nested case–control study (817 cases/ 817 controls) within the European Prospective Investigation ...
  • Barriers and facilitators when implementing family involvement for persons with psychotic disorders in community mental health centres - a nested qualitative study 

    Hansson, Kristiane Myckland; Romøren, Maria; Pedersen, Reidar; Weimand, Bente Margrethe; Hestmark, Lars; Norheim, Irene; Ruud, Torleif; Stølan Hymer, Inger; Heiervang, Kristin Sverdvik (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-12)
    <b><p>Background</b> The uptake of family involvement in health care services for patients with psychotic disorders is poor, despite a clear evidence base, socio-economic and moral justifications, policy, and guideline recommendations. To respond to this knowledge-practice gap, we established the cluster randomised controlled trial: Implementation of guidelines on Family Involvement for persons ...
  • Seroprevalence of antibodies against SARS-CoV-2 in the adult population during the pre-vaccination period, Norway, winter 2020/21 

    Anda, Erik Eik; Braaten, Tonje Bjørndal; Borch, Kristin Benjaminsen; Nøst, Therese Haugdahl; Chen, Sairah Lai Fa; Lukic, Marko; Lund, Eiliv; Forland, Frode; Leon, David Andrew; Askeland Winje, Brita; Kran, Anne-Marte Bakken; Kalager, Mette; Lund-Johansen, Fridtjof; Sandanger, Torkjel M (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-31)
    Background: Since March 2020, 440 million people worldwide have been diagnosed with COVID-19, but the true number of infections with SARS-CoV-2 is higher. SARS-CoV-2 antibody seroprevalence can add crucial epidemiological information about population infection dynamics. Aim: To provide a large population-based SARS-CoV-2 seroprevalence survey from Norway; we estimated SARS-CoV-2 seroprevalence before ...
  • The Norwegian PraksisNett: a nationwide practice-based research network with a novel IT infrastructure 

    Kristoffersen, Espen Saxhaug; Bjorvatn, Bjørn; Halvorsen, Peder Andreas; Nilsen, Stein; Fossum, Guro Haugen; Fors, Egil Andreas; Jørgensen, Pål; Øxnevad-Gundersen, Berit; Gjelstad, Svein; Bellika, Johan Gustav; Straand, Jørund; Rørtveit, Guri (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-13)
    Clinical research in primary care is relatively scarce. Practice-based research networks (PBRNs) are research infrastructures to overcome hurdles associated with conducting studies in primary care. In Norway, almost all 5.4 million inhabitants have access to a general practitioner (GP) through a patient-list system. This gives opportunity for a PBRN with reliable information about the general ...
  • Introducing Lightweight IT – A Way to Build Flexibility for Healthcare Organizations? 

    Severinsen, Gro-Hilde; Silsand, Line; Malm-Nicolaisen, Kristian; Pedersen, Rune; Ellingsen, Gunnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2022)
    The paper addresses socio technical relations of implementing a lightweight IT app in Norway. The focus is on how such technology will influence the possibilities for an organization connected to a large-scale heavyweight IT infrastructure to provide more rapid changes in line with healthcare worker’s needs. The research question is therefore: How can lightweight IT support rapid organizational ...
  • Scaling AI Projects for Radiology– Causes and Consequences 

    Ellingsen, Gunnar; Silsand, Line; Severinsen, Gro-Hilde; Linstad, Line Helen (Journal article; Tidsskriftartikkel; Peer reviewed, 2022)
    Artificial intelligence (AI) for radiology has the potential to handle an ever-increasing volume of imaging examinations. However, the implementation of AI for clinical practice has not lived up to expectations. We suggest that a key problem with AI projects in radiology is that high expectations associated with new and unproven AI technology tend to scale the projects in ways that challenge their ...
  • Pain, discomfort, and functional impairment after extraction of primary teeth in children with palatally displaced canines–a randomized control trial comparing extraction of the primary canine versus extraction of the primary canine and the primary first molar 

    Hadler-Olsen, Sigurd; Steinnes, Jeanett; Nermo, Hege; Sjögren, Anders; Hadler-Olsen, Elin Synnøve (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-09)
    Objective - To assess pain, discomfort, and functional impairment in children experiencing extraction of primary canine or primary canine and primary first molar as an interceptive treatment for palatally displaced permanent canines.<p> <p>Material and methods - Twenty-eight children, aged 9.5–14 years with displaced permanent maxillary canines were randomly assigned for extraction of the primary ...
  • Adverse cardiovascular events and mortality in men during testosterone treatment: an individual patient and aggregate data meta-analysis 

    Hudson, Jemma; Cruickshank, Moira; Quinton, Richard; Aucott, Lorna; Aceves-Martins, Magaly; Gillies, Katie; Bhasin, Shalender; Snyder, Peter J; Ellenberg, Susan S; Grossmann, Mathis; Travison, Thomas G; Gianatti, Emily J; van der Schouw, Yvonne T; Emmelot-Vonk, Marielle H; Giltay, Erik J; Hackett, Geoff; Ramachandran, Sudarshan; Svartberg, Johan; Hildreth, Kerry L; Groti Antonic, Kristina; Brock, Gerald B; Tenover, J Lisa; Tan, Hui Meng; Kong, Christopher Ho Chee; Tan, Wei Shen; Marks, Leonard S; Ross, Richard J; Schwartz, Robert S; Manson, Paul; Roberts, Stephen; Andersen, Marianne; Magnussen, Line Velling; Hernández, Rodolfo; Oliver, Nick; Wu, Frederick; Dhillo, Waljit S; Bhattacharya, Siladitya; Brazzelli, Miriam; Jayasena, Channa N (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-09)
    Background Testosterone is the standard treatment for male hypogonadism, but there is uncertainty about its cardiovascular safety due to inconsistent findings. We aimed to provide the most extensive individual participant dataset (IPD) of testosterone trials available, to analyse subtypes of all cardiovascular events observed during treatment, and to investigate the effect of incorporating data ...
  • Sexual Harassment and Abuse among Young Elite Athletes, Recreational Athletes, and Reference Students: A Prospective Study 

    Sølvberg, Nina; Torstveit, Monica Klungland; Rosenvinge, Jan H; Pettersen, Gunn; Sundgot-Borgen, Jorunn (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11)
    Purpose: To examine the 12-months prevalence and 12-months prospective change in reported sexual harassment and abuse (SHA)-victimization among young elite athletes, recreational athletes, and reference students in three different social settings and identify the perpetrators. Methods: In total, 919 adolescents responded to an online questionnaire in 12th grade (T1) and 13th grade (T2). The ...

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