Recent additions

  • Tuning of Liver Sieve: The Interplay between Actin and Myosin Regulatory Light Chain Regulates Fenestration Size and Number in Murine Liver Sinusoidal Endothelial Cells 

    Zapotoczny, Barlomiej; Szafranska, Karolina; Lekka, Malgorzata; Ahluwalia, Balpreet Singh; McCourt, Peter Anthony (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-30)
    Liver sinusoidal endothelial cells (LSECs) facilitate the efficient transport of macromolecules and solutes between the blood and hepatocytes. The efficiency of this transport is realized via transcellular nanopores, called fenestrations. The mean fenestration size is 140 ± 20 nm, with the range from 50 nm to 350 nm being mostly below the limits of diffraction of visible light. The cellular ...
  • Quality of life following renal sympathetic denervation in treatment-resistant hypertensive patients: a two-year follow-up study 

    Hanssen, Tove Aminda; Subbotina, Anna; Miroslawska, Atena; Solbu, Marit Dahl; Steigen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-10)
    Objective. Hypertension is a significant health burden. In the last 10 years, renal sympathetic denervation has been tested as a potential treatment option for a select group of patients with treatmentresistant hypertension. The aim of this study was to broadly assess the quality of life in patients undergoing renal sympathetic denervation with two years’ follow-up. Materials and methods. Patients ...
  • Lifestyle factors as mediators of area-level socio-economic differentials in cardiovascular disease risk factors. The Tromsø Study 

    Tiwari, Sweta; Cerin, Ester; Wilsgaard, Tom; Løvsletten, Ola; Njølstad, Inger; Grimsgaard, Sameline; Hopstock, Laila Arnesdatter; Schirmer, Henrik; Rosengren, Annika; Kristoffersen, Kathrine; Løchen, Maja-Lisa (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-24)
    Introduction: Cardiovascular disease (CVD) is a leading cause of death and disability and living in areas with low socio-economic status (SES) is associated with increased risk of CVD. Lifestyle factors such as smoking, physical inactivity, an unhealthy diet and harmful alcohol use are main risk factors that contribute to other modifiable risk factors, such as hypertension, raised blood cholesterol, ...
  • Circulating free testosterone and risk of aggressive prostate cancer: Prospective and Mendelian randomisation analyses in international consortia 

    Watts, Eleanor L.; Perez-Cornago, Aurora; Fensom, Georgina K.; Smith-Byrne, Karl; Noor, Urwah; Andrews, Colm D.; Gunter, Marc J.; Holmes, Michael V.; Martin, Richard M.; Tsilidis, Konstantinos K.; Albanes, Demetrius; Barricarte, Aurelio; Bueno-de-Mesquita, Bas; Chen, Chu; Cohn, Barbara A.; Dimou, Niki L.; Ferrucci, Luigi; Flicker, Leon; Freedman, Neal D.; Giles, Graham G.; Giovannucci, Edward L.; Goodman, Gary E.; Haiman, Christopher A.; Hankey, Graeme J.; Huang, Jiaqi; Huang, Wen-Yi; Hurwitz, Lauren M.; Kaaks, Rudolf; Knekt, Paul; Kubo, Tatsuhiko; Langseth, Hilde; Laughlin, Gail; Le Marchand, Loic; Luostarinen, Tapio; MacInnis, Robert J.; Mäenpää, Hanna O.; Männistö, Satu; Metter, E. Jeffrey; Mikami, Kazuya; Mucci, Lorelei A.; Olsen, Anja; Ozasa, Kotaro; Palli, Domenico; Penney, Kathryn L.; Platz, Elizabeth A.; Rissanen, Harri; Sawada, Norie; Schenk, Jeannette M.; Stattin, Pär; Tamakoshi, Akiko; Thysell, Elin; Tsai, Chiaojung Jillian; Tsugane, Shoichiro; Vatten, Lars Johan; Weiderpass, Elisabete; Weinstein, Stephanie J.; Wilkens, Lynne R.; Yeap, Bu B.; Allen, Naomi E.; Key, Timothy J.; Travis, Ruth C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-17)
    Previous studies had limited power to assess the associations of testosterone with aggressive disease as a primary endpoint. Further, the association of genetically predicted testosterone with aggressive disease is not known. We investigated the associations of calculated free and measured total testosterone and sex hormone-binding globulin (SHBG) with aggressive, overall and early-onset prostate ...
  • How does indirect air-cooling influence pulp chamber temperature in different volume teeth and absence/presence of resin-based composite during light curing? 

    Mouhat, Mathieu; Stangvaltaite-Mouhat, Lina; Finnäs, Emil; Andersen, Amani; Lirhus Evertsen, Anneli; Nilsen, Bo Wold (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-24)
    <p><b> Background</b> Light-curing of materials during restorative dental procedures poses a risk for pulp tissue overheating. Therefore, the aim of this study was to investigate the effect of indirect air-cooling on pulp chamber temperatures during light-curing of varying volume teeth and absence/presence of resin-based composite (RBC) at different exposure time. <p><b> Methods</b> The ...
  • Do adolescents exposed to peer aggression at school consider themselves to be victims of bullying? The influence of sex and age 

    Vieira, Marlene A.; Handegård, Bjørn Helge; Rønning, John Andreas; Duarte, Cristine S.; Mari, Jair J.; Bordin, Isabel A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-10)
    <p><b> Introduction</b> Exposure to peer aggression (PA) and bullying victimization (BV) are both expressions of peer victimization. <p><b> Objectives</b> In four age-sex groups, (1) Can exposure to PA and BV be considered distinct experiences? (2) To what extent do adolescents exposed to PA consider themselves bullying victims? and (3) What is the effect on BV of the number of PA events ...
  • Høyt nivå av tungmetaller i krabbe 

    Averina, Maria; Monsen, Anne-Lise Bjørke; Bolann, Bjørn Johan; Brox, Jan; Eggesbø, Merete; Hokstad, Ingrid; Huber, Sandra; Ørebech, Peter Th (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-01)
    Krabber er populær sjømat, men kan inneholde til dels store mengder miljøgifter. Innholdet er mange steder i Norge så høyt at inntak av brunmaten generelt bør frarådes.
  • Laktat i fosterskalpblodprøve som markør for føtal hypoksi 

    Fosse, Gunhild Øygard; Averina, Maria (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-11)
    Evidensgrunnlaget for å ta blodprøver fra fosterskalpen er svakt. Fører prøvene til færre intervensjoner eller bedre utfall for fosteret?
  • Hvordan forbedre? 

    Joakimsen, Peder (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-13)
    Hei, det er vanskelig ut fra innlegget å se hva som faktisk skal kunne bidra til en «bredere rekrutteringsbase»
  • En mann i 40-årene med akutt forvirring 

    Karlberg, Merethe; Thoresen, Hanne; Berg, Diana Hristova; Ciopat, Oana-Gratiela; Alstadhaug, Karl Bjørnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-07)
    Rask og adekvat utredning av akutte nevropsykiatriske symptomer er avgjørende for effektiv behandling. Her beskriver vi en pasient med en karakteristisk, men relativt sjelden sykdom.
  • Pre-diagnostic DNA methylation in blood leucocytes in cutaneous melanoma; a nested case–control study within the Norwegian Women and Cancer cohort 

    Page, Christian Magnus; Nøst, Therese Haugdahl; Djordjilović, Vera; Thoresen, Magne; Frigessi, Arnoldo; Sandanger, Torkjel M; Veierød, Marit Bragelien (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-20)
    The prognosis of cutaneous melanoma depends on early detection, and good biomarkers for melanoma risk may provide a valuable tool to detect melanoma development at a pre-clinical stage. By studying the epigenetic profile in pre-diagnostic blood samples of melanoma cases and cancer free controls, we aimed to identify DNA methylation sites conferring melanoma risk. DNA methylation was measured at ...
  • Protocol of a mixed-method randomised controlled pilot study evaluating a wilderness programme for adolescent and young adult cancer survivors: the WAYA study 

    Jong, Miek; Mulder, Eric; Kristoffersen, Agnete Egilsdatter; Stub, Trine; Dahlqvist, Heléne; Viitasara, Eija; Lown, E Anne; Schats, Winnie; Jong, Mats (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-09)
    Introduction - The majority of childhood, adolescent and young adult (AYA) cancer survivors suffer from long-term and late effects such as fatigue, psychological distress or comorbid diseases. Effective health promotion strategies are needed to support the health of this vulnerable group. This protocol provides a methodological description of a study that aims to examine the feasibility and safety ...
  • Public and outpatients’ awareness of calling emergency medical services immediately by acute stroke in an upper middle-income country: a cross-sectional questionnaire study in greater Gaborone, Botswana 

    Ookeditse, Ookeditse; Ookeditse, Kebadiretse K.; Motswakadikgwa, Thusego R.; Masilo, Gosiame; Bogatsu, Yaone; Lekobe, Baleufi Calstro; Mosepele, Mosepele; Schirmer, Henrik; Johnsen, Stein Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-14)
    Objectives - In this cross-sectional study from Botswana, we investigated awareness of calling emergency medical services (EMS) and seeking immediate medical assistance by acute stroke among stroke risk outpatients and public.<p> <p>Method - Closed-ended questionnaires on awareness of calling EMS and seeking immediate medical assistance by acute stroke, were administered by research assistants ...
  • Adherence and persistence to pharmacotherapy in patients with heart failure: a nationwide cohort study, 2014–2020 

    Ødegaard, Kristina Malene; Lirhus, Sandre Svatun; Melberg, Hans Olav; Hallen, Jonas; Halvorsen, Sigrun (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-20)
    Aims - We aimed to study initiation, adherence, and long-term persistence to beta-blockers (BB), renin–angiotensin system inhibitors (RASi), and mineralocorticoid receptor antagonists (MRA) in a nationwide cohort of patients with heart failure (HF).<p> <p>Methods - Patients aged 18–80 years in Norway with a first diagnosis of HF from 2014 until 2020 that survived ≥30 days were identified from the ...
  • Transitioning patients with juvenile idiopathic arthritis to adult care: the Nordic experience 

    Mikola, Katriina; Rebane, Katariina; Arnstad, Ellen Dalen; Berntson, Lillemor; Fasth, Anders; Glerup, Mia; Herlin, Troels; Kautiainen, Hannu; Nielsen, Susan; Nordal, Ellen Berit; Peltoniemi, Suvi; Rygg, Marite; Rypdal, Veronika; Zak, Marek; Aalto, Kristiina (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-01)
    Background: With juvenile idiopathic arthritis (JIA), there are several protocols and practices used worldwide for the transition from paediatric to adult care. In this study, we examined the transferral rates and disease activity after transition, as well as the disease- and health-related outcomes. We also introduce the transition practices employed in the Nordic countries.<p> <p>Methods: The ...
  • Early surfactant and non-invasive ventilation versus intubation and surfactant: a propensity score-matched national study 

    Reigstad, Hallvard; Hufthammer, Karl Ove; Rønnestad, Arild Erland; Klingenberg, Claus Andreas; Stensvold, Hans Jørgen; Markestad, Trond Jacob (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-27)
    <p><b> Objective</b> To compare outcome after less invasive surfactant administration (LISA) and primary endotracheal intubation (non-LISA) in infants born before gestational age (GA) 28 weeks. <p><b> Setting</b> All neonatal intensive care units (NICUs) in Norway during 2012–2018. <p><b> Methods</b> Defined population-based data were prospectively entered into a national registry. We ...
  • Active commuting and work ability: A cross-sectional study of chicken meat industry workers in Thailand 

    Phanprasit, Wantanee; Chotiphan, Chotirot; Konthonbut, Pajaree; Laohaudomchok, Wisanti; Ikäheimo, Tiina; Jaakkola, Jouni J.K.; Näyhä, Simo (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-11)
    There is ample evidence regarding positive health effects of cycling or walking to work (active commuting [AC]). However, little is known about the effects of AC on work ability. Therefore, we examined 422 Thai chicken meat industry workers who assessed their current work ability (CWA) compared to their lifetime best by assigning scores ranging from 0 to 10. The CWA was compared between active ...
  • Using storytelling in undergraduate dental education: Students' experiences of emotional competence training 

    Johnsen, Jan-Are Kolset; Borit, Melania; Stangvaltaite-Mouhat, Lina (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-03)
    Aim: The aim of the study was to explore the use of storytelling as a teaching method for emotional competence interventions within undergraduate dental curriculum (dental and dental hygiene students).<p> <p>Materials and Methods: Students participated in five sessions related to emotional competence: one theoretical and four practical. During the latter, divided in small groups, students told ...
  • Lokalbehandling av utbrudd ved Hidrosadenitt 

    Lien, Ludvik Hovda (Master thesis; Mastergradsoppgave, 2020-11-13)
    <p>Bakgrunn: Hidrosadenitt (HS) er en kronisk inflammatorisk hudsykdom som kjennetegnes av et svingende forløp med hyppige residiv av smertefulle lesjoner. Tilstanden er en klinisk utfordring, spesielt da informasjon om best tilgjengelig behandling av disse utbruddene er vanskelig tilgjengelig for klinikere. Formålet med oppgaven er å undersøke dokumentasjonen bak disse behandlingsformene, også med ...
  • Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells 

    Vilaplana-Lopera, Nuria; Cuminetti, Vincent; Almaghrabi, Ruba; Papatzikas, Grigorios; Rout, Ashok Kumar; Jeeves, Mark; González, Elena; Alyahyawi, Yara; Cunningham, Alan; Erdem, Ayşegül; Schnütgen, Frank; Raghavan, Manoj; Potluri, Sandeep; Cazier, Jean-Baptiste; Schuringa, Jan Jacob; Reed, Michelle AC; Arranz, Lorena; Günther, Ulrich L; Garcia, Paloma (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-02)
    Acute myeloid leukaemia (AML) cells interact and modulate components of their surrounding microenvironment into their own benefit. Stromal cells have been shown to support AML survival and progression through various mechanisms. Nonetheless, whether AML cells could establish beneficial metabolic interactions with stromal cells is underexplored. By using a combination of human AML cell lines and AML ...

View more