Recent additions

  • Ultrasound assessed carotid atherosclerosis in a general population : the Tromsø study 

    Joakimsen, Oddmund (Doctoral thesis; Doktorgradsavhandling, 2000)
    As a neurologist with a special interest in cerebrovascular diseases, and with several years of practice with ultrasound examinations of extra- and intracranial arteries, I have some times experienced patients in whom ultrasound revealed unexpected findings which surprised mc, and made me wonder about etiological relationships and clinical implications. Thus, ultrasound examinations of the carotid ...
  • How life events are perceived to link to bodily distress: A qualitative study of women with chronic pelvic pain. 

    Boge-Olsnes, Cathrine Maria; Risør, Mette Bech; Øberg, Gunn Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-28)
    Chronic pelvic pain (CPP) is highly prevalent among women and the condition is poorly understood. In addition to multiple symptoms from the pelvis, CPP patients frequently suffer bodily distress like musculoskeletal pain and negative emotional, behavioral, and sexual implications. This paper is based on a qualitative study including semi-structured interviews with eight women with CPP. Our project ...
  • Boundary work in task-shifting practices – A qualitative study of reablement teams 

    Eliassen, Marianne; Moholt, Jill-Marit (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-18)
    Background - Health services worldwide have provided incentives for establishing teams to accommodate complex health care tasks, enhance patient outcomes and organizational efficiency, and compensate for shortages of health care professionals. Parallel to and partly due to the increased focus on teamwork, task shifting has become a health policy. Task shifting involves new tasks and responsibilities, ...
  • Novel screening methods for nanoscale changes in liver cell fenestrations elicited by pharmaceuticals 

    Szafranska, Karolina (Doctoral thesis; Doktorgradsavhandling, 2022-08-19)
    This thesis focuses on liver sinusoidal endothelial cells (LSEC) and one of their characteristic features called fenestrations. LSEC line the hepatic sinusoids and filter solutes from the plasma. The bidirectional transport of solutes between the bloodstream and the interior of the liver is facilitated via transcellular nanopores called fenestrations. Fenestrations are dynamic structures with diameters ...
  • Bisphenol A replacement chemicals, BPF and BPS, induce protumorigenic changes in human mammary gland organoid morphology and proteome 

    Winkler, Juliane; Liu, Pengyuan; Phong, Kiet; Hinrichs, Johanna H.; Ataii, Nassim; Williams, Katherine; Hadler-Olsen, Elin Synnøve; Samson, Susan; Gartner, Zev J.; Fisher, Susan; Werb, Zena (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-09)
    Environmental chemicals such as bisphenol A (BPA) are thought to contribute to carcinogenesis through their endocrine-disrupting properties. Due to accumulating evidence about negative human health effects, BPA is being phased out, but in parallel, exposures to replacement chemicals such as bisphenol S (BPS) and bisphenol F (BPF) are increasing. Little is known about their biologic effects, but ...
  • Dental plaque and gingival bleeding in adolescents with juvenile idiopathic arthritis and controls: a multilevel analysis 

    Gil, Elisabeth Grut; Åstrøm, Anne-Kristine N; Lie, Stein Atle; Rygg, Marite; Fischer, Johannes; Rosén, Annika; Bletsa, Athanasia; Luukko, Keijo Aukusti; Shi, Xie-Qi; Halbig, Josefine Mareile; Frid, Paula Hanna Therese; Cetrelli, Lena Elisabet; Tylleskär, Karin; Rosendahl, Karen; Skeie, Marit Slåttelid (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-30)
    Objective - To explore whether plaque and gingival bleeding are more frequently experienced by adolescents with juvenile idiopathic arthritis (JIA) compared to matched controls without JIA; explore whether surface- and site-specific periodontal outcomes vary between the two groups; and for participants with JIA, investigate associations between disease-specific features and periodontal outcomes.<p ...
  • Occupational cold exposure is associated with neck pain, low back pain, and lumbar radiculopathy 

    Stjernbrandt, Albin; Farbu, Erlend Hoftun (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-24)
    Ambient cold exposure can pose health risks, and this study was aimed at investigating associations with musculoskeletal disorders. A postal survey was performed on 12,627 men and women, ages 18–70 years, living in northern Sweden. Statistical associations were determined using multiple logistic regression. The study sample consisted of 6,886 women (54.5%), and 5,741 men. Reporting high occupational ...
  • Targeting Internalizing Symptoms in Children: What is the Impact on School Functioning? 

    Pedersen, Marit Løtveit; Holen, Solveig; Sund, Anne Mari; Adolfsen, Frode; Løvaas, Mona Elisabeth S; Martinsen, Kristin; Neumer, Simon-Peter; Patras, Joshua; Rasmussen, Lene-Mari Potulski; Lydersen, Stian (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-13)
    Internalizing problems may be associated with poor academic performance and school absenteeism among youth. This study investigated the impact of the EMOTION: “Coping Kids” Managing Anxiety and Depression Program on academic achievement and school adaptation in children. Data were collected in a national cluster-randomized controlled trial at three time points in Norway. Children (N = 688, 8–12 ...
  • “It was an important part of my treatment”: a qualitative study of Norwegian breast Cancer patients’ experiences with mainstreamed genetic testing 

    Strømsvik, Nina; Olsson, Pernilla Marie A.; Gravdehaug, Berit; Lurås, Hilde; Schlichting, Ellen; Jørgensen, Kjersti; Wangensteen, Teresia; Vamre, Tone; Heramb, Cecilie; Mæhle, Lovise Olaug; Grindedal, Eli Marie (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-05)
    Background - In South-Eastern Norway, genetic testing for BRCA1 and BRCA2 is offered to breast cancer patients by their treating surgeon or oncologist. Genetic counselling from a geneticist or a genetic counsellor is offered only to those who test positive for a pathogenic variant or have a family history of cancer. This practice is termed “mainstreamed genetic testing”. The aim of this study was ...
  • The impact of case factors on the initial screening decision in child welfare investigations in Norway 

    Rustad, Kirsten Buck; Lauritzen, Camilla; Havnen, Karen J Skaale; Fossum, Sturla; Christiansen, Øivin; Vis, Svein Arild (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-15)
    Background - When a child welfare service agency receives a report of concern, there is an initial screening to decide whether an investigation needs to be initiated. In addition to the decision maker, case factors, external factors, and organizational factors have an impact on decision making in Child Welfare Services (CWS). Few recent studies have considered the impact of case factors on the initial ...
  • Er det forskjell i behandlingsresultat mellom pasienter som besvarer spørreskjema om utfall etter nakkekirurgi og pasienter som ikke gjør det? 

    Aune, Grethe; Karlsen, Martine Eriksen (Master thesis; Mastergradsoppgave, 2020-08-05)
    Bakgrunn og formål: Oppgaven er en valideringsstudie basert på data fra Nasjonalt kvalitetsregister for rygg- og nakkekirurgi (NKR). Validiteten til kvalitetsregistre er avhengig av tilstrekkelig høy responsrate for at konklusjonene som trekkes angående effekt av en behandling skal være korrekte. Formålet med studien er å analysere om det er forskjell i behandlingsresultat mellom pasienter som ...
  • Identifying predictive signalling networks for Vedolizumab response in ulcerative colitis. 

    Singh, A.; Fenton, Christopher Graham; Anderssen, Endre; Paulssen, Ruth H (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-11)
    Background - In ulcerative colitis (UC), the molecular mechanisms that drive disease development and patient response to therapy are not well understood. A significant proportion of patients with UC fail to respond adequately to biologic therapy. Therefore, there is an unmet need for biomarkers that can predict patients’ responsiveness to the available UC therapies as well as ascertain the most ...
  • Unintentional response priming from verbal action–effect instructions 

    Damanskyy, Yevhen; Martiny-Huenger, Torsten; Parks-Stamm, Elizabeth J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-02)
    Action–effect learning is based on a theoretical concept that actions are associated with their perceivable consequences through bidirectional associations. Past research has mostly investigated how these bidirectional associations are formed through actual behavior and perception of the consequences. The present research expands this idea by investigating how verbally formulated action–effect ...
  • Accuracy and agreement of national spine register data for 474 patients compared to corresponding electronic patient records 

    Alhaug, Ole Kristian; Kaur, Simran; Dolatowski, Filip C; Småstuen, Milada Cvancarova; Solberg, Tore; Lønne, Greger (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-06)
    Purpose - Data quality is essential for all types of research, including health registers. However, data quality is rarely reported. We aimed to assess the accuracy of data in a national spine register (NORspine) and its agreement with corresponding data in electronic patient records (EPR).<p> <p>Methods - We compared data in NORspine registry against data in (EPR) for 474 patients operated for ...
  • Explaining risk reductions in medical practice : prevention or postponement? 

    Halvorsen, Peder Andreas (Doctoral thesis; Doktorgradsavhandling, 2008)
    Diagnosis, treatment and follow up of risk conditions such as hypercholesterolemia and osteoporosis are prominent tasks of contemporary medical practice. The aim is to prevent, or at least postpone the onset of adverse health outcomes such as angina pectoris, heart attacks, strokes and fractures. Dealing with risks involves decision making under uncertainty. For patients to be able to engage ...
  • Screen-detected and interval breast cancer after concordant and discordant interpretations in a population based screening program using independent double reading 

    Martiniussen, Marit Almenning; Sagstad, Silje; Larsen, Marthe; Larsen, Anne Sofie Frøyshov; Hovda, Tone; Lee, Christoph I.; Hofvind, Solveig Sand-Hanssen (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-02)
    Objectives - To analyze rates, odds ratios (OR), and characteristics of screen-detected and interval cancers after concordant and discordant initial interpretations and consensus in a population-based screening program.<p> <p>Methods - Data were extracted from the Cancer Registry of Norway for 487,118 women who participated in BreastScreen Norway, 2006–2017, with 2 years of follow-up. All mammograms ...
  • Medication adherence among persons with coronary heart disease and associations with blood pressure and low-density-lipoprotein-cholesterol 

    Pedersen, Elisabeth; Primicerio, Raul; Halvorsen, Kjell H.; Eggen, Anne Elise; Garcia, Beate Hennie; Schirmer, Henrik; Waaseth, Marit (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-21)
    Purpose - To describe medication adherence to lipid-lowering drugs (LLDs), antihypertensive drugs, and acetylsalicylic acid (ASA) among persons with coronary heart disease (CHD) and explore its association with low-density-lipoprotein (LDL)-cholesterol, and systolic and diastolic blood pressure.<p> <p>Methods - Based on record linkage between the seventh wave of the Tromsø Study and the Norwegian ...
  • Automated segmentation of magnetic resonance bone marrow signal: a feasibility study 

    von Brandis, Elisabeth; Jenssen, Håvard Bjørke; Avenarius, Derk Frederik Matthaus; Bjørnerud, Atle; Flatø, Berit; Tomterstad, Anders; Lilleby, Vibke; Rosendahl, Karen; Sakinis, Tomas; Zadig, Pia Karin Karlsen; Müller, Lil-Sofie Ording (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-02)
    Background - Manual assessment of bone marrow signal is time-consuming and requires meticulous standardisation to secure adequate precision of findings.<p> <p>Objective - We examined the feasibility of using deep learning for automated segmentation of bone marrow signal in children and adolescents.<p> <p>Materials and methods - We selected knee images from 95 whole-body MRI examinations of ...
  • Protocol for Isolation and Culture of Mouse Hepatocytes (HCs), Kupffer Cells (KCs), and Liver Sinusoidal Endothelial Cells (LSECs) in Analyses of Hepatic Drug Distribution 

    Elvevold, Kjetil; Kyrrestad, Ingelin; Smedsrød, Bård (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-25)
    Development of the new generation of drugs (e.g., oligo- and polynucleotides administered intravascularly either as free compounds or as nano-formulations) frequently encounters major challenges such as lack of control of targeting and/or delivery. Uncontrolled or unwanted clearance by the liver is a well-known and particularly important hurdle in this respect. Hence, reliable techniques are needed ...
  • Iron status and prevalence of hereditary haemochromatosis in a multiethnic population in northern Norway : the SAMINOR study, the Sør-Varanger study, the Tromsø V study 

    Broderstad, Ann Ragnhild (Doctoral thesis; Doktorgradsavhandling, 2008)
    Iron status is influenced by several factors such as nutritional factors and blood loss. Tron deficiency is one of the most severe and important nutritional deficiencies in the world today, both in industrialised as well as developing countries [1-3]. In normal subjects the total daily loss of iron is balanced by an equivalent amount of iron absorbed from the diet. When this equilibrium is ...

View more