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CALCOCO1 is a soluble reticulophagy receptor
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-25)The endoplasmic reticulum (ER) is the largest membrane-bound organelle in eukaryotic cells and plays critical roles in diverse processes in metabolism, signaling and intracellular organization. In response to stress stimuli such as nutrient deprivation, accumulation of misfolded proteins or exposure to chemicals, the ER increases in size through upregulated synthesis of its components to counteract ... -
Capture of a novel, antibiotic resistance encoding, mobile genetic element from Escherichia coli using a new entrapment vector
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-01)<b><p>Aims</b> Antimicrobial resistance genes (ARGs) are often associated with mobile genetic elements (MGEs), which facilitate their movement within and between bacterial populations. Detection of mobility is therefore important to understand the dynamics of MGE dissemination and their associated genes, especially in resistant clinical isolates that often have multiple ARGs associated with MGEs. ... -
Chapter 11 - Hydrogels as intrinsic antimicrobials
(Chapter; Bokkapittel, 2019-10-25)Hydrogels are currently applied as the vehicles for drugs or active substances, rather than the active contributors to therapeutic activities. With increasing challenges related to antimicrobial resistance against many antibiotics, natural origin hydrogels have become attractive as more than just vehicles. Although many natural polymers exhibit intrinsic antimicrobial properties, these properties ... -
Cryoneurolysis for cervicogenic headache - A double blinded randomized controlled study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-13)Background and aims - Cervicogenic headache (CEH) is a debilitating condition and analgesics have limited effect. Percutaneous cryoneurolysis is thus still in use although the clinical evidence is lacking. We present a randomized, controlled study to assess the clinical efficacy of cryoneurolysis compared with a corticosteroid combined with a local anaesthetic. <p> <p>Methods - In a university-based ... -
Pain tolerance after stroke: The Tromsø study
(Journal article; Tidsskriftartikkel, 2023-05-11)Background: Stroke lesions might alter pain processing and modulation by affecting the widely distributed network of brain regions involved. We aimed to compare pain tolerance in stroke survivors and stroke-free persons in the general population, with and without chronic pain.<p> <p>Methods: We included all participants of the sixth and seventh wave of the population-based Tromsø Study who had ... -
Fremmer ettervern selvstendighet eller avhengighet? (Kronikk)
(Chronicle; Kronikk, 2018)Å forstå unge med barnevernsbakgrunn som en ressurssvak gruppe med særskilte behov er en grov generalisering av en svært sammensatt gruppe. -
Young football players' dietary beliefs and practices - a qualitative study
(Master thesis; Mastergradsoppgave, 2023-06-01)The purpose of this master's thesis is to investigate the dietary habits and beliefs among young football players and to examine whether there are differences between those participating in private sports programs in Eastern Norway and those participating in public sports programs in Finnmark. Through qualitative interviews with six young football players, the study has found that young athletes ... -
Friluftslivlærere sine erfaringer med samiske perspektiver i undervisningen. En kvalitativ studie fra Knut Hamsun videregående skole
(Master thesis; Mastergradsoppgave, 2023-05-15)I denne studien undersøkes lærere i friluftslivsfag ved Knut Hamsun videregående skole sine erfaringer med samiske perspektiver i undervisningen. Studien har tatt for seg hva som fremmer og hemmer det samiske perspektivet, rammebetingelsene lærerne må forholde seg til og hva lærerne helt konkret gjør for å implementere det samiske perspektivet i undervisningen. Studiens vitenskapsteoretiske posisjon ... -
Hyppighet og alvorlighetsgrad av selvopplevde menstruasjonssymptomer og bivirkninger ved bruk av hormonell prevensjon, sett i sammenheng med fysisk aktivitet i idrett og trening blant norske håndballspillere
(Master thesis; Mastergradsoppgave, 2023-05-15)Bakgrunn: Kvinner er svært underrepresentert når det gjelder idrett og trening i vitenskapelig forskning sammenlignet med menn. En forståelse av symptomer i menstruasjonssyklusen og bivirkninger ved bruk av hormonell prevensjon (HP) kan bidra til å optimalisere prestasjon i idrett og trening blant kvinner. Hensikt: Målet med denne oppgaven var å undersøke (1) hvordan naturlig menstruerende (NM), ... -
Prevalence of menstrual cycle disturbances and hormonal contraception use in Norwegian women of differing activity levels: a part of the FENDURA project
(Master thesis; Mastergradsoppgave, 2023-05-15)<p>Background: A lack of research on female exercise physiology and sports psychology has resulted in considerable knowledge gaps regarding the optimal training methods and recommendations for the female athletic population, as current evidence is based primarily on research dominated by male participants. In order to conduct relevant and applicable research on the athletic female population, ... -
Physical Activity and Quality of Life among Substance Use Disorder Patients – An Observational Pilot study
(Master thesis; Mastergradsoppgave, 2023-05-14)<p>Introduction: Substance abuse is a global health concern that affects individuals, families, and communities worldwide. Regular and sufficient physical activity (PA) has proven to have a positive effect on key elements in substance use disorder (SUD) treatment. The aim of this study was to examine participation in PA and the association of PA with health-related physical fitness, and quality of ... -
Uncovering the influence of contextual factors on short peak periods in Women`s football
(Master thesis; Mastergradsoppgave, 2023-05-12)<p>Aim: The purpose of the present study was to investigate whether different contextual factors influence short peak periods, and further uncover its reasons for variability, in female football matches. Different rolling average (RA) time periods (10, 30 and 60 seconds) was applied. <p>Methods: With an observational study design, 59 players from four elite women’s football teams in Norway`s top ... -
Utredning og behandling av annen spesifisert urininkontinens hos kvinner under 40 år ved UNN Tromsø. En retrospektiv kvalitetsstudie
(Master thesis; Mastergradsoppgave, 2023-08-18)Urininkontinens i enhver form er en relativt vanlig tilstand blant kvinner, og forekomsten er økende og tilstanden bidrar til redusert livskvalitet. I denne oppgaven fokuserer jeg på diagnosekoden N39.4 Annen spesifisert urininkontinens som inkluderer pasienter med urgeinkontinens, overaktiv blæresyndrom og blandingsinkontinens. Hovedformålet med oppgaven er å kartlegge utredning og behandling av ... -
Penicillin for enhver pris?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-26)Barn i trassalderen og bitre penicillinblandinger fire ganger i døgnet er en vanskelig kombinasjon. Smalspektret antibiotika er gullstandarden, men må balanseres opp mot barnets ubehag og etterlevelse av behandlingen. -
Survival after cancer-related venous thrombosis: the Scandinavian Thrombosis and Cancer Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-28)Patients with cancer have an increased risk of developing venous thromboembolism (VTE), and this combination is reported to result in poorer survival compared with cancer alone. This study aimed to investigate the impact of VTE on the survival of patients with cancer in a general population. The Scandinavian Thrombosis and Cancer (STAC) cohort, a population-based cohort including 144 952 participants ... -
Treatment Preferences in Young Adults with Moderate to Severe Psoriasis: A Qualitative Study from the Nordic Countries
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-15)Introduction - The purpose of this study is to explore treatment preferences and identify patient characteristics in young bio-naive adults with moderate to severe psoriasis in the Nordic countries (Norway, Finland, Sweden, and Denmark).<p> <p>Methods - Patients were 18–45 years old and bio-naive but referred for biologic treatment of moderate to severe psoriasis. Patients were included at eight ... -
Efficacy of Aggression Replacement Training among Children from North-West Russia
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014-11)The aim of the study was to assess whether the Aggression Replacement Training (ART) programme is effective in increasing social skills and decreasing problem behaviour. The sample consisted of 232 children (mean age 10.9 yrs, SD = 2.32), their parents and teachers. The study had a quasi-experimental design with intervention and control groups. Children were recruited from six schools and four social ... -
Lung cancer risk discrimination of prediagnostic proteomics measurements compared with existing prediction tools
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-01)Background: We sought to develop a proteomics-based risk model for lung cancer and evaluate its risk-discriminatory performance in comparison with a smoking-based risk model (PLCOm2012) and a commercially available autoantibody biomarker test.<p><p>Methods: We designed a case-control study nested in 6 prospective cohorts, including 624 lung cancer participants who donated blood samples at most 3 ... -
Immunization with lytic polysaccharide monooxygenase CbpD induces protective immunity against Pseudomonas aeruginosa pneumonia
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-17)Pseudomonas aeruginosa (PA) CbpD belongs to the lytic polysaccharide monooxygenases (LPMOs), a family of enzymes that cleave chitin or related polysaccharides. Here, we demonstrate a virulence role of CbpD in PA pneumonia linked to impairment of host complement function and opsonophagocytic clearance. Following intratracheal challenge, a PA ΔCbpD mutant was more easily cleared and produced less ... -
Clustering and trajectories of key noncommunicable disease risk factors in Norway: the NCDNOR project
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-02)Noncommunicable diseases (NCDs) are a leading cause of premature death globally and have common preventable risk factors. In Norway, the NCDNOR-project aims at establishing new knowledge in the prevention of NCDs by combining information from national registries with data from populationbased health studies. In the present study, we aimed to harmonize data on key NCD risk factors from the health ...
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