Recent additions

  • “Falling off the wagon”: older adults’ experiences of living with frailty in rural arctic communities 

    Bjerkmo, Lena; Helgesen, Ann Karin; Larsen, Toril Agnete; Blix, Bodil H. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-12)
    Most populations around the world are ageing. The proportion of older adults in the population is larger and is growing more rapidly in rural communities than in urban areas. Longevity increases the risk of frailty. Our aim was to explore how single-living frail older adults experience living with frailty in everyday life in rural Arctic areas. Over eight months, we conducted a series of three ...
  • Prediction of thyroid nodule histopathology by expert ultrasound evaluation 

    Håskjold, Olav Inge; Foshaug, Henrik Stenestø; Iversen, Therese Benedikte; Kjøren, Helga Charlotte; Brun, Vegard Heimly (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-17)
    <i>Objective</i> - The basis of thyroid nodule diagnostics is ultrasound-guided fine needle biopsy with cytological evaluation (FNC) if ultrasound appearance is not clearly benign. The aim of this study was to investigate the predictive potential of dedicated, expert high-resolution ultrasound, to see if histopathological entities of thyroid nodules can be diagnosed without invasive FNC biopsies.< ...
  • Changes in maternal risk factors and their association with changes in cesarean sections in Norway between 1999 and 2016: A descriptive population-based registry study 

    Skjeldestad, Finn Egil; Møllersen, Kajsa; Eik Anda, Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-03)
    Background - Increases in the proportion of the population with increased likelihood of cesarean section (CS) have been postulated as a driving force behind the rise in CS rates worldwide. The aim of the study was to assess if changes in selected maternal risk factors for CS are associated with changes in CS births from 1999 to 2016 in Norway.<p> <p>Methods and findings - This national ...
  • Adverse events reporting by obstetric units in Norway as part of their quality assurance and patient safety work: an analysis of practice 

    Johansen, Lars Thomas; Braut, Geir Sverre; Acharya, Ganesh; Andresen, Jan Fredrik; Øian, Pål (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-08)
    Background - The Norwegian Board of Health Supervision aims to contribute to the improvement of quality and patient safety in the healthcare services. Planned audits were performed to investigate how 12 selected Norwegian obstetric units reported and analyzed adverse events as the part of their quality assurance and patient safety work.<p> Methods - Serious adverse events coded as birth asphyxia, ...
  • Nitric oxide, oxidative stress and streptococcus mutans and lactobacillus bacterial loads in saliva during the different stages of pregnancy: A longitudinal study 

    Wagle, Madhu; Basnet, Purusotam; Vårtun, Åse; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-03)
    Hormonal changes associated with pregnancy promote oral bacterial growth, which may affect salivary nitric oxide (NO) levels, oxidative stress (OS), and antioxidant capacity (AC). We hypothesized that caries-related bacterial load, NO level, and OS in the saliva change with advancing gestation. The aim of this study was to investigate longitudinal changes in salivary NO, OS, and AC during pregnancy ...
  • Severe acute respiratory syndrome coronavirus 2 prevalence in 1170 asymptomatic Norwegian conscripts 

    Borud, Einar Kristian; Nakstad, Espen Rostrup; Håberg, Siri Eldevik; Lind, Andreas; Fadum, Elin Anita; Taxt, Arne Michael; Steens, Anneke; Gjein, Gaute Eriksen; Sunde, Magne Wiken; Iversen, Petter; Svanevik, Marius; Ahmad, Babar Mushtaq; Waldow, Thomas; Norheim, Arne Johan (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-15)
    <i>Background</i> - Accurate estimates of SARS-CoV-2 infection in different population groups are important for the health authorities. In Norway, public infection control measures have successfully curbed the pandemic. However, military training and service are incompatible with these measures; therefore extended infection control measures were implemented in the Norwegian Armed Forces. We aimed ...
  • Hippocampus-Avoidance Whole-Brain Radiation Therapy Is Efficient in the Long-Term Preservation of Hippocampal Volume 

    Popp, Ilinca; Rau, Alexander; Kellner, Elias; Reisert, Marco; Fennell, Jamina; Rothe, Thomas; Nieder, Carsten; Urbach, Horst; Egger, Karl; Grosu, Anca L.; Kaller, Christoph P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-19)
    Background and Purpose: With improved life expectancy, preventing neurocognitive decline after cerebral radiotherapy is gaining more importance. Hippocampal damage has been considered the main culprit for cognitive deficits following conventional whole-brain radiation therapy (WBRT). Here, we aimed to determine to which extent hippocampus-avoidance WBRT (HA-WBRT) can prevent hippocampal atrophy ...
  • A two-lab direct replication attempt of Southgate, Senju and Csibra (2007) 

    Kampis, D.; Kármán, P.; Csibra, G.; Southgate, V.; Hernik, M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-25)
    The study by Southgate et al. (2007 Psychol. Sci.18, 587–592. (doi:10.1111/j.1467-9280.2007.01944.x)) has been widely cited as evidence for false-belief attribution in young children. Recent replication attempts of this paradigm have yielded mixed results: several studies did not replicate the original findings, raising doubts about the suitability of the paradigm to assess non-verbal action prediction ...
  • Healthcare professionals' knowledge of modifiable stroke risk factors: A cross-sectional questionnaire survey in greater Gaborone, Botswana 

    Ookeditse, Ookeditse; Motswakadikgwa, Thusego R.; Ookeditse, Kebadiretse K.; Masilo, Gosiame; Bogatsu, Yaone; Lekobe, Baleufi Calstro; Mosepele, Mosepele; Schirmer, Henrik; Johnsen, Stein Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-27)
    Background - Stroke remains the second leading cause of deaths and disability globally, with highest mortality in Africa (low- and middle-income countries). It is crucial for healthcare professionals to have sufficient stroke risk factors' knowledge in order to reduce the stroke burden. <p> <p>Aims - We investigated healthcare professionals' knowledge of modifiable stroke risk factors, and ...
  • High expression of miR-17-5p in tumor epithelium is a predictor for poor prognosis for prostate cancer patients 

    Støen, Maria Jenvin; Andersen, Sigve; Rakaee, Mehrdad; Pedersen, Mona Irene; Ingebriktsen, Lise Martine; Bremnes, Roy M.; Dønnem, Tom; Lombardi, Ana Paola; Kilvær, Thomas Karsten; Rasmussen Busund, Lill-Tove; Richardsen, Elin (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-05)
    MicroRNAs (miRs) are small non-coding RNA molecules, which are involved in the development of various malignancies, including prostate cancer (PCa). miR-17-5p is considered the most prominent member of the miR-17-92 cluster, with an essential regulatory function of fundamental cellular processes. In many malignancies, up-regulation of miR-17-5p is associated with worse outcome. In PCa, miR-17-5p has ...
  • Combined Lifestyle Behaviors and the Incidence of Common Cancer Types in the Norwegian Women and Cancer Study (NOWAC) 

    Chen, Sairah Lai Fa; Braaten, Tonje Bjørndal; Borch, Kristin Benjaminsen; Ferrari, Pietro; Sandanger, Torkjel M; Nøst, Therese Haugdahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-16)
    <i>Introduction</i>: Only a small number of studies have examined the impact of combined lifestyle behaviors on cancer incidence, and never in a Norwegian population.<br><br> <i>Purpose</i>: To examine linear and nonlinear associations of combined lifestyle factors, assessed through a healthy lifestyle index (HLI), with the incidence of postmenopausal breast, colorectal, lung, postmenopausal ...
  • Treatment of cardiovascular dysfunction with PDE5-inhibitors - temperature dependent effects on transport and metabolism of cAMP and cGMP 

    Selli, Anders Lund; Kuzmiszyn, Adrina Kalasho; Smaglyukova, Natalia; Kondratiev, Timofei V.; Fuskevåg, Ole Martin; Lyså, Roy Andre; Ravna, Aina Westrheim; Tveita, Torkjel; Sager, Georg; Dietrichs, Erik Sveberg (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-30)
    <i>Introduction</i>: Cardiovascular dysfunction is a potentially lethal complication of hypothermia. Due to a knowledge gap, pharmacological interventions are not recommended at core temperatures below 30°C. Yet, further cooling is induced in surgical procedures and survival of accidental hypothermia is reported after rewarming from below 15°C, advocating a need for evidence-based treatment guidelines. ...
  • Role of Virus-Induced Host Cell Epigenetic Changes in Cancer 

    Pietropaolo, Valeria; Prezioso, Carla; Moens, Ugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-03)
    The tumor viruses human T-lymphotropic virus 1 (HTLV-1), hepatitis C virus (HCV), Merkel cell polyomavirus (MCPyV), high-risk human papillomaviruses (HR-HPVs), Epstein-Barr virus (EBV), Kaposi’s sarcoma-associated herpes virus (KSHV) and hepatitis B virus (HBV) account for approximately 15% of all human cancers. Although the oncoproteins of these tumor viruses display no sequence similarity to one ...
  • Antenatal breastmilk expression for women with diabetes in pregnancy - a feasibility study 

    Johnsen, Maren; Klingenberg, Claus; Brand, Meta; Revhaug, Arthur; Andreassen, Gunnbjørg (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-23)
    <i>Background</i> - Mothers with diabetes are less likely to achieve successful breastfeeding. Antenatal breastmilk expression (ABE) may facilitate earlier breastfeeding, but feasibility of introducing ABE and its acceptance among Scandinavian women have previously not been investigated.<br><br> <i>Methods</i> - This observational trial was conducted between the 1 January 2019 and the 12 March ...
  • Community Violence Exposure and School Functioning in Youth: Cross-Country and Gender Perspectives 

    Koposov, Roman A; Isaksson, Johan; Vermeiren, Robert; Schwab-Stone, Mary; Stickley, Andrew; Ruchkin, Vladislav (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-27)
    <i>Background</i>: Many children and adolescents experience violent events which can be associated with negative consequences for their development, mental health, school, and social functioning. However, findings between settings and on the role of gender have been inconsistent. This study aimed to investigate cross-country and gender differences in the relationship between community violence ...
  • Myelomatose i Nord-Norge 2005-2015 

    Lauvås, Kenneth (Master thesis; Mastergradsoppgave, 2017-09-20)
    Bakgrunn: Myelomatose er den tredje vanligste hematologiske kreftsykdommen med en insidensrate på 6,5 per 100,000. Sykdommen kjennetegnes av akkumulering av plasmaceller i beinmargen, og utvikler seg alltid gjennom forstadiet MGUS. Symptomene er lite spesifikke og diagnostikken er omfattende. Myelomatose meldes til kreftregisteret, men kreftregisteret publiserer ikke overlevelsesdata for landet som ...
  • Dioxin-like activity in blood from women with breast cancer and their age-matched controls 

    Nedrebø, Lise Custers (Master thesis; Mastergradsoppgave, 2017-09-20)
    Breast cancer is the most common cancer in women today, and although many risk factors are known, these cannot fully explain the vast increase in breast cancer incidences the last decades. Persistent organic pollutants have been indicated as potential carcinogenic compounds and it is therefore interesting to see if they can be a factor in the development of the disease. Here, we assessed the ...
  • When is remission remission? Elucidating the remission state in Ulcerative Colitis: a multimodal exploration 

    Arkteg, Christian Børde (Doctoral thesis; Doktorgradsavhandling, 2021-10-22)
    Ulcerative Colitis (UC) is a chronic, inflammatory disease of the colon that has a relapsing-remitting characteristic. The disease management consists of prolonging periods of remission and reducing relapse frequency. There is currently no universally accepted definition of remission in UC. There are different methods of establishing if a patient is in remission, but the lack of definition and ...
  • Systematisk oversikt over sykestueforskning med vekt på kvalitet, økonomi og pasientforløp 

    Nilsen, Karoline Damsgård (Master thesis; Mastergradsoppgave, 2017-09-17)
    Introduksjon: Samhandlingsreformen og den nye helse- og omsorgstjenesteloven påla alle kommuner å opprette øyeblikkelig hjelp døgntilbud fra 1.1.2016. Intermediærenheter som sykestuer har de siste tiårene fått økende fokus både i Norge og i utlandet. Målet med denne oppgaven er å lage en systematisk oversikt over forskningslitteratur som omhandler sykestuer med vekt på kvalitet, økonomi og ...
  • The use of commercial ELISA kits in measuring CA6 concentration of saliva 

    Machlik, Edit; Woll, Emilie Elise (Mastergradsoppgave; Master thesis, 2021-05-20)
    Introduction: Carbonic anhydrase 6 (CA6) is the only secreted member of the carbonic anhydrase enzyme family. This enzyme catalyzes the reversible hydration of carbon dioxide: CO2 + H2O ⇔ H+ + HCO3-. The dehydration reaction contributes to net acidification in several tissues and biological fluids. Salivary CA6 attaches to the enamel and predisposes to caries probably by acidifying the dental biofilm ...

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