Recent additions

  • EKG-forandringer ved bruk av SSRI, ett litteraturstudium 

    Jaatun, Vebjørn Rikardsen (Master thesis; Mastergradsoppgave, 2021-05-24)
    Formålet med oppgaven var å se på effekten av ulike SSRI på QTc-intervallet i kliniske studier. SSRI er en gruppe antidepressiva som er hyppig brukt og er ansett å ha generelt svært god bivirkningsprofil sammenliknet med tidligere legemiddelgrupper. Et US FDA-advarsel fra 2011 assosierte derimot SSRI-et citalopram med forlengelse av QTc-intervallet. Dermed blir det av interesse å sammenlikne ...
  • Er korttidsresultater etter kirurgi for tykktarmskreft blitt bedre med moderne perioperative metoder? 

    Nylund, Ida (Master thesis; Mastergradsoppgave, 2021-05-31)
    Innledning: Tykktarmskreft er blant de vanligste kreftdiagnosene i Norge, og kirurgi er primærbehandlingen. Korttidsresultater etter kirurgisk behandling avhenger av mange faktorer. Siste 15 år har det tilkommet en rekke nye behandlingsmetoder og perioperative regimer til kolorektal kirurgi. Formålet med studien er å undersøke om korttidsresultater ved kirurgi for tykktarmskreft ved UNN Tromsø er ...
  • Caffeine for treating apnea in premature babies - A literary review 

    Kristiansen, Christel Brekke (Master thesis; Mastergradsoppgave, 2021-05-31)
    Premature infants with pulmonary complications is becoming a substantial health care problem. Apnea of prematurity being one of the biggest challenges that may end in death with no or wrongful treatment. Non-invasive respiratory support has been the favorable alternative, and caffeine citrate has been the drug of choice since the 1970s. The aim of this study was to explore how effective caffeine is ...
  • Medikamentell primærprofylakse mot venøs tromboembolisme hos polikliniske kreftpasienter - en systematisk oversikt og narrativ analyse 

    Larsen, Emilie Moss (Master thesis; Mastergradsoppgave, 2021-05-31)
    Bakgrunn: VTE er den hyppigst forekommende årsaken til død hos kreftpasienter etter selve kreftsykdommen. På tross av at kreftpasienter har svært høy risiko for utvikling av VTE, er ikke forebyggende behandling rutinemessig anbefalt i nåværende retningslinjer. Hensikten med denne oppgaven var å lage en oversikt over kliniske studier som har undersøkt medikamentell primærprofylaktisk behandling mot ...
  • Midterm outcomes for stemless hemiarthroplasty for glenohumeral osteoarthritis A retrospective study 

    Robertsen, Marit Katarina (Master thesis; Mastergradsoppgave, 2021-05-31)
    Osteoarthritis is the most common form of arthritis. For glenohumeral osteoarthritis the gold standard treatment for end stage disease is arthroplasty with stemmed prosthesis. The trend surrounding shoulder arthroplasty focuses on reducing stem-related complication, but mid- to long-term studies on stemless hemiarthroplasty are needed to evaluate durability. Our hypothesis was that stemless ...
  • Fremtidens leger - En ensartet eller mangfoldig og multikulturell gruppe? 

    Ellingsen, Hanna Elise (Master thesis; Mastergradsoppgave, 2021-05-30)
    Bakgrunn: I dag baserer opptak til medisinstudiet i Norge seg i stor grad på karakterer og mange tar opp fag ved dyre privatgymnas for å øke sitt karaktersnitt. Norges befolkning blir stadig mer etnisk og kulturelt mangfoldig, og det kreves stadig større kulturell kompetanse for å kunne tilby gode helsetjenester til hele befolkningen. Målet med denne oppgaven er å undersøke om dagens opptaksordninger ...
  • Brukere av MiniMed 670G ved medisinsk avdeling, UNN 

    Johansen, Mats Olsen (Master thesis; Mastergradsoppgave, 2021-05-27)
    Oppgavens formål er å undersøke hvilken effekt insulinpumpen MiniMed 670G har på HbA1c, hypoglykemiske episoder og livskvalitet sammenlignet med andre former for behandling ved diabetes mellitus type 1 (DM1). Studien er en retrospektiv kontrollert kvalitetssikringsstudie av 116 pasienter diagnostisert med DM1 som behandles ved medisinsk poliklinikk ved UNN Tromsø. Intervensjonsgruppen brukte MiniMed ...
  • Carbapenem resistance determinants acquired through novel chromosomal integrations in extensively drug-resistant pseudomonas aeruginosa 

    Janice, Jessin; Agyepong, Nicholas; Owusu-Ofori, Alex; Govinden, Usha; Essack, Sabiha; Samuelsen, Ørjan; Sundsfjord, Arnfinn; Pedersen, Torunn (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-17)
    Two novel bla<sub>DIM-1</sub>- or bla<SUB>IMP-1</SUB>-containing genomic islands (GIs) were discovered by whole-genome sequence analyses in four extensively drug-resistant (XDR) <i>Pseudomonas aeruginosa</i> isolates from inpatients at a tertiary hospital in Ghana. The strains were of sequence type 234 (ST234) and formed a phylogenetic clade together with ST111, which is recognized as a global ...
  • Native American social work – Including family and community 

    Swanson, Shanley; Nygård, Reidunn Håøy; Saus, Merete (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-05)
    <i>Summary</i> - This study investigates family involvement and culturally informed social work in Native American communities. The study was conducted in Native American communities in Montana, USA. Twenty-three Native American social work professionals participated in qualitative interviews. Analyses draw on theory of historical trauma and family involvement in indigenous social. Throughout the ...
  • New clinical data on human spinal cord re-irradiation tolerance 

    Doi, Hiroshi; Tamari, Keisuke; Oh, Ryoong-Jin; Nieder, Carsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-05)
    <i>Purpose</i> - To provide additional clinical data about the re-irradiation tolerance of the spinal cord.<br><br> <i>Methods</i> - This was a retrospective bi-institutional study of patients re-irradiated to the cervical or thoracic spinal cord with minimum follow-up of 6 months. The maximum dose (Dmax) and dose to 0.1cc (D0.1cc) were determined (magnetic resonance imaging [MRI]-defined cord) ...
  • Overexpression of mir-20a-5p in tumor epithelium is an independent negative prognostic indicator in prostate cancer—a multi-institutional study 

    Stoen, Maria J.; Andersen, Sigve; Rakaee, Mehrdad; Pedersen, Mona I.; Ingebriktsen, Lise M.; Dønnem, Tom; Lombardi, Ana P. G.; Kilvaer, Thomas K.; Rasmussen Busund, Lill-Tove; Richardsen, Elin (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-14)
    <i>Objective</i>: assessing the prognostic role of miR-20a-5p, in terms of clinical outcome, in a large multi-institutional cohort study.<br><br> <i>Methods</i>: Tissue microarrays from 535 patients’ prostatectomy specimens were constructed. In situ hybridization was performed to assess the expression level of miR-20a-5p in different tissue subregions: tumor stroma (TS) and tumor epithelium (TE). ...
  • The hers and his of prosociality across 10 countries 

    Olsson, Maria; Froehlich, Laura; Dorrough, Angela R.; Martiny, Sarah E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-19)
    Is there a ‘more helpful’ gender? The present research assessed gender differences in prosocial self-perceptions, prosocial behavioural intentions, and prosocial (transfer) behaviour in same- and other-gender interactions in 10 countries (N = 1,915). The present results showed negligible differences in the degree to which women and men saw themselves as prosocial. However, larger gender differences ...
  • Conditions and strategies to meet the challenges imposed by the COVID-19-related visiting restrictions in the intensive care unit: A Scandinavian cross-sectional study 

    Jensen, Hanne Irene; Åkerman, Eva; Lind, Ranveig; Alfheim, Hanne Birgit; Frivold, Gro; Fridh, Isabell; Ågård, Anne Sophie (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-26)
    <p>Objectives: To examine conditions and strategies to meet the challenges imposed by the coronavirus disease 2019 (COVID-19)-related visiting restrictions in Scandinavian intensive care units. <p>Research methodology/design: A cross-sectional survey. <p>Setting: Adult intensive care units in Denmark, Norway and Sweden. <p>Main outcome measures: Likert scale responses and free-text comments within ...
  • Antenatal breastmilk expression for women with diabetes in pregnancy - a feasibility study 

    Johnsen, Maren; Klingenberg, Claus; Brand, Meta; Revhaug, Arthur; Andreassen, Gunnbjørg (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-23)
    <p>Background: Mothers with diabetes are less likely to achieve successful breastfeeding. Antenatal breastmilk expression (ABE) may facilitate earlier breastfeeding, but feasibility of introducing ABE and its acceptance among Scandinavian women have previously not been investigated. <p>Methods: This observational trial was conducted between the 1 January 2019 and the 12 March 2020 in Tromsø, Norway. ...
  • Stanozolol-N-glucuronide metabolites in human urine samples as suitable targets in terms of routine anti-doping analysis 

    Göschl, Lorenz; Gmeiner, Günter; Gärtner, Peter; Stadler, Georg; Enev, Valentin; Thevis, Mario; Schänzer, Wilhelm; Guddat, Sven; Forsdahl, Guro (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-05)
    The exogenous anabolic-androgenic steroid (AAS) stanozolol stays one of the most detected substances in professional sports. Its detection is a fundamental part of doping analysis, and the analysis of this steroid has been intensively investigated for a long time. This contribution to the detection of stanozolol doping describes for the first time the unambiguous proof for the existence of ...
  • Non-radiologist-performed abdominal point-of-care ultrasonography in paediatrics — a scoping review 

    van Wassenaer, Elsa A.; Daams, Joost G.; Benninga, Marc A.; Rosendahl, Karen; Koot, Bart G.P.; Stafrace, Samuel; Arthurs, Owen J.; van Rijn, Rick R. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-10)
    <i>Background</i> - Historically, US in the paediatric setting has mostly been the domain of radiologists. However, in the last decade, there has been an uptake of non-radiologist point-of-care US.<br><br> <i>Objective</i> - To gain an overview of abdominal non-radiologist point-of-care US in paediatrics.<br><br> <i>Materials and methods</i> - We conducted a scoping review regarding the uses ...
  • A prognostic model for failure and worsening after lumbar microdiscectomy: a multicenter study from the Norwegian Registry for Spine Surgery 

    Werner, David Andreas Thomas; Grotle, Margreth; Småstuen, Milada Cvancarova; Gulati, Sasha; Nygaard, Øystein Petter; Salvesen, Øyvind; Ingebrigtsen, Tor; Solberg, Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-10)
    <i>Objective</i> - To develop a prognostic model for failure and worsening 1 year after surgery for lumbar disc herniation.<br><br> <i>Methods</i> - This multicenter cohort study included 11,081 patients operated with lumbar microdiscectomy, registered at the Norwegian Registry for Spine Surgery. Follow-up was 1 year. Uni- and multivariate logistic regression analyses were used to assess potential ...
  • A combined effect of anti-HPA-1a and anti-HLA Class I in pregnancy? 

    Dahl, Jesper; Skogen, Bjørn; Kjær, Mette; Husebekk, Anne; Kjeldsen-Kragh, Jens; Tiller, Heidi (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-30)
    <i>Background</i> - Maternal anti–human leukocyte antigen (HLA) Class I is commonly detected alongside anti–human platelet antigen (HPA)-1a in fetal and neonatal alloimmune thrombocytopenia (FNAIT). Little is known regarding whether the presence of anti-HLA Class I may exert an additive effect on the risk and severity of FNAIT.<br><br> <i>Methods and Materials</i> - We reanalyzed samples originally ...
  • Estimated Glomerular Filtration Rate (eGFR) based on cystatin C was associated with increased risk of hip and proximal humerus fractures in women and decreased risk of hip fracture in men, whereas eGFR based on creatinine was not associated with fracture risk in both sexes: The Tromsø Study 

    Nordvåg, Sofie; Solbu, Marit Dahl; Melsom, Toralf; Nissen, Frida Igland; Andreasen, Camilla; Borgen, Tove Tveitan; Eriksen, Bjørn Odvar; Joakimsen, Ragnar Martin; Bjørnerem, Åshild (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-14)
    <i>Purpose</i> - Patients with end-stage kidney disease have an increased fracture risk. Whether mild to moderate reductions in kidney function is associated with increased fracture risk is uncertain. Results from previous studies may be confounded by muscle mass because of the use of creatinine-based estimates of the glomerular filtration rate (eGFRcre). We tested the hypothesis that lower eGFR ...
  • The educational gradient in intake of energy, macro- and micronutrients in the Tromsø Study 2015-2016 

    Nilsen, Linn (Master thesis; Mastergradsoppgave, 2020-05-27)
    <p>Background: Socioeconomic status is associated with inequalities in health. Unhealthy diet is a risk factor for non-communicable diseases, and socioeconomic inequalities exists also in diet. <p>Aim: To investigate the relationship between educational level and the intake of total energy, macro- and micronutrients. <p>Participants: 11,302 individuals (40-96 years) from Tromsø, Norway. <p>Methods: ...

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