Recent additions

  • Grain and dietary fiber intake and bladder cancer risk: a pooled analysis of prospective cohort studies 

    Yu, Evan Y W; Wesselius, Anke; Mehrkanoon, Siamak; Brinkman, Maree; van den Brandt, Piet; White, Emily; Weiderpass, Elisabete; Le Calvez-Kelm, Florence; Gunter, Marc; Huybrechts, Inge; Liedberg, Fredrik; Skeie, Guri; Tjonneland, Anne; Riboli, Elio; Giles, Graham; Milne, Roger L; Zeegers, Maurice P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-10)
    Background - Higher intakes of whole grains and dietary fiber have been associated with lower risk of insulin resistance, hyperinsulinemia, and inflammation, which are known predisposing factors for cancer.<p> <p>Objectives - Because the evidence of association with bladder cancer (BC) is limited, we aimed to assess associations with BC risk for intakes of whole grains, refined grains, and dietary ...
  • Comparing Calculated Nutrient Intakes Using Different Food Composition Databases: Results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Cohort 

    Van Puyvelde, Heleen; Perez-Cornago, Aurora; Casagrande, Corinne; Nicolas, Geneviève; Versele, Vickà; Skeie, Guri; Schulze, Matthias B.; Johansson, Ingegerd; Huerta, José María; Oliverio, Andreina; Ricceri, Fulvio; Halkjær, Jytte; Etxezarreta, Pilar Amiano; Van Herck, Koen; Weiderpass, Elisabete; Gunter, Marc J.; Huybrechts, Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-23)
    This study aimed to compare calculated nutrient intakes from two different food composition databases using data from the European prospective investigation into cancer and nutrition (EPIC) cohort. Dietary intake data of the EPIC cohort was recently matched to 150 food components from the U.S. nutrient database (USNDB). Twenty-eight of these nutrients were already included in the EPIC nutrient ...
  • Demographic variation in fit note receipt and long-term conditions in south London 

    Dorrington, Sarah; Carr, Ewan; Stevelink, Sharon A. M.; Dregan, Alexandru; Whitney, David; Durbaba, Stevo; Ashworth, Mark; Mykletun, Arnstein; Broadbent, Matthew; Madan, Ira; Hatch, Stephani; Hotopf, Matthew (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-24)
    Objectives - Introduced in the UK in 2010, the fit note was designed to address the problem of long-term sickness absence. We explored (1) associations between demographic variables and fit note receipt, ‘maybe fit’ use and long-term conditions, (2) whether individuals with long-term conditions receive more fit notes and are more likely to have the ‘maybe fit’ option selected and (3) whether long-term ...
  • 'You should see a doctor', said the robot: Reflections on a digital diagnostic device in a pandemic age 

    Haase, Christoffer Bjerre; Bearman, Margaret; Brodersen, John; Hoeyer, Klaus; Risør, Torsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-18)
    Aims: In three days at the beginning of the COVID-19 pandemic, the Copenhagen Emergency Medical Services developed a digital diagnostic device. The purpose was to assess and triage potential COVID-19 symptoms and to reduce the number of calls to public health-care helplines. The device was used almost 150,000 times in a few weeks and was described by politicians and administrators as a solution and ...
  • Consumption of Fish and Long-chain n-3 Polyunsaturated Fatty Acids Is Associated With Reduced Risk of Colorectal Cancer in a Large European Cohort 

    Aglago, Elom Kouassivi; Huybrechts, Inge; Murphy, Neil; Casagrande, Corinne; Nicolas, Geneviève; Pischon, Tobias; Fedirko, Veronika; Severi, Gianluca; Boutron-Ruault, Marie-Christine; Fournier, Agnès; Katzke, Verena Andrea; Kühn, Tilman; Olsen, Anja; Tjønneland, Anne; Dahm, Christina C.; Overvad, Kim; Lasheras, Cristina; Agudo, Antonio; Sanchez, Maria-Jose; Amiano, Pilar; Huerta, Jose Maria; Ardanaz, Eva; Perez-Cornago, Aurora; Trichopoulou, Antonia; Karakatsani, Anna; Martimianaki, Georgia; Bueno-De-Mesquita, Bas; May, Anne; Derksen, Jeroen W.G.; Hellstrand, Sophie; Ohlsson, Bodil; Wennberg, Maria; Van Guelpen, Bethany; Skeie, Guri; Brustad, Magritt; Weiderpass, Elisabete; Cross, Amanda J.; Ward, Heather; Riboli, Elio; Norat, Teresa; Chajes, Veronique; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-25)
    Background & Aims - There is an unclear association between intake of fish and long-chain n-3 polyunsaturated fatty acids (n-3 LC-PUFAs) and colorectal cancer (CRC). We examined the association between fish consumption, dietary and circulating levels of n-3 LC-PUFAs, and ratio of n-6:n-3 LC-PUFA with CRC using data from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. ...
  • Female genital self-image in women with and without female genital mutilation/cutting in Jeddah, Saudi Arabia 

    Rouzi, Abdulrahim A.; Berg, Rigmor; Alamoudi, Rana; Alzaban, Faten; Sehlo, Mohammad (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-29)
    Introduction - The consequences of female genital mutilation/cutting (FGM/C) on female genital self-image are not known.<p> <p>Aim - To assess whether women with and without FGM/C differed with regard to female genital self-image.<p> <p>Methods - A survey was administered to a group of women attending the King Abdulaziz University Hospital obstetrics and gynecology clinic from December 2016 ...
  • Combined Influence of Waist and Hip Circumference on Risk of Death in a Large Cohort of European and Australian Adults 

    Cameron, Adrian J.; Romaniuk, Helena; Orellana, Liliana; Dallongeville, Jean; Dobson, Annette J; Drygas, Wojciech; Ferrario, Marco; Ferrieres, Jean; Giampaoli, Simona; Gianfagna, Francesco; Iacoviello, Licia; Jousilahti, Pekka; Kee, Frank; Moitry, Marie; Niiranen, Teemu J; Pajak, Andrzej; Palmieri, Luigi; Palosaari, Tarja; Mannisto, Satu; Tamosiunas, Abdonas; Thorand, Barbara; Toft, Ulla; Vanuzzo, Diego; Salomaa, Veikko; Veronesi, Giovanni; Wilsgaard, Tom; Kuulasmaa, Kari; Söderberg, Stefan (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-30)
    Background - Waist circumference and hip circumference are both strongly associated with risk of death; however, their joint association has rarely been investigated.<p> <p>Methods and Results - The MONICA Risk, Genetics, Archiving, and Monograph (MORGAM) Project was conducted in 30 cohorts from 11 countries; 90 487 men and women, aged 30 to 74 years, predominantly white, with no history of ...
  • A possible effect of montelukast on neurological aging examined by the use of register data 

    Grinde, Bjørn; Schirmer, Henrik; Eggen, Anne Elise; Aigner, Ludwig; Engdahl, Bo Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-09)
    Background - The leukotriene receptor antagonist montelukast has been shown to rejuvenate aged brains in rats; however, data on humans are still scarce. Objective To investigate if montelukast may alleviate degenerative neurological changes using a register data. Setting Norwegian registry data analyses. <p> <p>Method - The present observational study was based on data from the Norwegian Prescription ...
  • Barn og unges medvirkning i barnevernet: en systematisk kartleggingsoversikt 

    Ormstad, Sari Susanna; Hestevik, Christine Hillestad; Munthe-Kaas, Heather Menzies; Blaasvær, Nora; Muller, Ashley Elizabeth; Berg, Rigmor (Research report; Forskningsrapport, 2020)
    Barn har rett til å medvirke i alle saker som vedrører dem. Barne-, ungdoms- og familiedirektoratet (Bufdir) ønsket en oversikt over forskning som har undersøkt barn og unges medvirkning i barnevernet: 1) hvordan barn og unge involveres i barnevernet, 2) barn og unges opplevelser med og preferanser for medvirkning, 3) dilemmaer knyttet til medvirkning, og 4) effektene av medvirkning.<p> <p>Metode ...
  • Serologic markers of Chlamydia trachomatis and other sexually transmitted infections and subsequent ovarian cancer risk: Results from the EPIC cohort 

    Idahl, Annika; Le Cornet, Charlotte; González Maldonado, Sandra; Waterboer, Tim; Bender, Noemi; Tjønneland, Anne; Hansen, Louise; Boutron-Ruault, Marie-Christine; Fournier, Agnès; Kvaskoff, Marina; Boeing, Heiner; Trichopoulou, Antonia; Valanou, Elissavet; Peppa, Eleni; Palli, Domenico; Agnoli, Claudia; Mattiello, Amalia; Tumino, Rosaria; Sacerdote, Carlotta; Onland-Moret, N. Charlotte; Gram, Inger Torhild; Weiderpass, Elisabete; Quirós, J. Ramón; Duell, Eric J.; Sánchez, Maria-Jose; Chirlaque, Maria-Dolores; Barricarte, Aurelio; Gil, Leire; Brändstedt, Jenny; Riesbeck, Kristian; Lundin, Eva; Khaw, Kay-Tee; Perez-Cornago, Aurora; Gunter, Marc; Dossus, Laure; Kaaks, Rudolf; Fortner, Renée T. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-03)
    A substantial proportion of epithelial ovarian cancer (EOC) arises in the fallopian tube and other epithelia of the upper genital tract; these epithelia may incur damage and neoplastic transformation after sexually transmitted infections (STI) and pelvic inflammatory disease. We investigated the hypothesis that past STI infection, particularly Chlamydia trachomatis, is associated with higher EOC ...
  • Smoking-Related Risks of Colorectal Cancer by Anatomical Subsite and Sex 

    Gram, Inger Torhild; Park, Song-Yi; Wilkens, Lynne R; Haiman, Christopher A.; Le Marchand, Loïc (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-23)
    The purpose of this study was to examine whether the increased risk of colorectal cancer due to cigarette smoking differed by anatomical subsite or sex. We analyzed data from 188,052 participants aged 45–75 years (45% men) who were enrolled in the Multiethnic Cohort Study in 1993–1996. During a mean follow-up period of 16.7 years, we identified 4,879 incident cases of invasive colorectal adenocarcinoma. ...
  • C-reactive protein-guided antibiotic prescribing for COPD exacerbations: A qualitative evaluation 

    Phillips, Rhiannon; Stanton, H.; Singh-Mehta, A.; Gillespie, David; Bates, Janine; Gal, Micaela; Thomas-Jones, Emma; Lowe, Rachel; Hood, Kerenza; Llor, Carl; Melbye, Hasse; Cals, Jochen; White, Patrick; Butler, Christopher C.; Francis, Nick (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-25)
    Background - Antibiotics are prescribed to >70% of patients presenting in primary care with an acute exacerbation of chronic obstructive pulmonary disease (AECOPD). The PACE randomised controlled trial found that a C-reactive protein point-of-care test (CRP-POCT) management strategy for AECOPD in primary care resulted in a 20% reduction in patient-reported antibiotic consumption over 4 weeks.<p> <p>Aim ...
  • Metachronous Contralateral Testicular Cancer in the Cisplatin Era: A Population-Based Cohort Study 

    Hellesnes, Ragnhild; Myklebust, Tor Åge; Bremnes, Roy M.; Karlsdottir, Åsa; Kvammen, Øivind; Negaard, Helene Francisca Stigter; Tandstad, Torgrim; Wilsgaard, Tom; Fosså, Sophie Dorothea; Haugnes, Hege Sagstuen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-23)
    PURPOSE - It is hypothesized that cisplatin-based chemotherapy (CBCT) reduces the occurrence of metachronous contralateral (second) germ cell testicular cancer (TC). However, studies including treatment details are lacking. The aim of this study was to assess the second TC risk, emphasizing the impact of previous TC treatment.<p> <p>PATIENTS AND METHODS - Based on the Cancer Registry of Norway, ...
  • Prognostic value of absolute quantification of mutated KRAS in circulating tumour DNA in lung adenocarcinoma patients prior to therapy 

    Wahl, Sissel Gyrid Freim; Hong, Yan Dai; Emdal, Elisabeth Fritzke; Ottestad, Anine Larsen; Dale, Vibeke Grotnes; Richardsen, Elin; Halvorsen, Tarje Onsøien; Grønberg, Bjørn Henning (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-27)
    Droplet digital polymerase chain reaction (ddPCR) is a highly sensitive and accurate method for quantification of nucleic acid sequences. We used absolute quantification of mutated v‐Ki‐ras2 Kirsten rat sarcoma viral oncogene homology gene (KRAS) by ddPCR to investigate the prognostic role of mutated KRAS in patients with KRAS‐mutated lung adenocarcinomas. Pre‐treatment plasma samples from 60 patients ...
  • Urinary excretion of epidermal growth factor and rapid loss of kidney function 

    Norvik, Jon Viljar; Harskamp, Laura R.; Nair, Viji; Shedden, Kerby; Solbu, Marit Dahl; Eriksen, Bjørn Odvar; Kretzler, Matthias; Gansevoort, Ron T.; Ju, Wenjun; Melsom, Toralf (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-17)
    Background - Lower urinary excretion of the kidney tubule–specific biomarker epidermal growth factor (uEGF) is associated with increased risk of renal function [glomerular filtration rate (GFR)] loss in diabetes and in patients with established chronic kidney disease (CKD). We investigated whether uEGF is associated with rapid GFR decline or incident CKD in the general population.<p> <p>Methods ...
  • Machine learning algorithms performed no better than regression models for prognostication in traumatic brain injury 

    Gravesteijn, BY; Nieboer, Daan; Ercole, Ari; Lingsma, Hester F; Nelson, David; Van Calster, Ben; Steyerberg, Ewout W; Andelic, Nada; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-19)
    <i>Objective</i> - We aimed to explore the added value of common machine learning (ML) algorithms for prediction of outcome for moderate and severe traumatic brain injury.<br><br> <i>Study Design and Setting</i> - We performed logistic regression (LR), lasso regression, and ridge regression with key baseline predictors in the IMPACT-II database (15 studies, <i>n</i> = 11,022). ML algorithms ...
  • User requirements meet large-scale EHR suites: Norwegian preparations for Epic 

    Ellingsen, Gunnar; Hertzum, Morten (Journal article; Tidsskriftartikkel; Peer reviewed, 2020)
    Electronic health records (EHRs) are becoming the norm in healthcare. Typically, these EHRs are large-scale suite systems. The up-front presence of ready-for-use EHR suites changes the role of user requirements and the conditions for deciding which requirements to include in the final contract. In this paper, we investigate how user requirements are negotiated in the ongoing preparations for the ...
  • The effect of atmospheric pressure on oxygen saturation and dyspnea: the Tromsø study 

    Dohmen, Lisa M. E.; Spigt, Mark; Melbye, Hasse (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-03)
    A drop in atmospheric pressure, as observed at high altitudes, leads to decreased oxygen saturation. The effect of regular changes in barometric pressure at sea level has never been studied in a general population. A cohort of adults aged 40 years were examined with pulse oximetry at two separate visits, and the local barometric pressure was available from the local weather station. The study aimed ...
  • Fremtider 

    Risør, Torsten; Waltorp, Karen; Juul Jensen, Uffe (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-23)
    Der mangler ikke udfordringer for sundhed, sygdom og samfund i fremtiden. Ofte nævnes demografiske ændringer – en ældre befolkning og øget migration – som væsentlige grunde til forandring: flere med kroniske sygdomme og medfølgende risiko for flere indlæggelser og polyfarmaci; øget spredning af infektionssygdomme; forekomst af genetiske sygdomme i nye befolkningsgrupper. Direkte og indirekte ...
  • Stress and perceived health among primary care visitors in two corners of Europe: Scandinavia and Greece 

    Koppner, Jenny; Chatziarzenis, Marios; Faresjö, Tomas; Theodorsson, Elvar; Thorsell, Annika; Nilsson, Staffan; Olsen, Ole; Faresjö, Åshild Olsen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-04)
    Background - The global financial crisis emerging in 2008 struck Greece especially hard, whereas Scandinavian countries were less affected. This has created a unique opportunity to study the long-term effect of community stress on populations. Increasing frequencies of mental health issues and poorer perceived health among the Greek population have been reported. The physiological marker of long-term ...

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