Recent additions

  • Psychometric properties of the Brief Problem Monitor (BPM) in children with internalizing symptoms: examining baseline data from a national randomized controlled intervention study 

    Pedersen, Marit Løtveit; Jozefiak, Thomas; Sund, Anne Mari; Holen, Solveig; Neumer, Simon-Peter; Martinsen, Kristin D.; Rasmussen, Lene Mari P.; Patras, Joshua; Lydersen, Stian (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-27)
    Background - Prevention is essential to reduce the development of symptomology among children and adolescents into disorders, thereby improving public health and reducing costs. Therefore, easily administered screening and early assessment methods with good reliability and validity are necessary to effectively identify children’s functioning and how these develop. The Brief Problem Monitor (BPM) is ...
  • Tocilizumab increases citrullinated histone 3 in non-ST segment elevation myocardial infarction 

    Helseth, Ragnhild; Kleveland, Ola; Ueland, Thor; Wiseth, Rune; Damås, Jan Kristian; Broch, Kaspar; Michelsen, Annika Elisabet; Bendz, Bjørn; Gullestad, Lars; Aukrust, Pål; Seljeflot, Ingebjørg (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-10)
    Objective: Beyond reducing inflammation and troponin T (TnT) release, the interleukin-6 receptor antagonist tocilizumab reduces neutrophil counts in patients with non-ST segment elevation myocardial infarction (NSTEMI). It is unclear if this is related to formation of neutrophil extracellular traps (NETs), carrying inflammatory and thrombotic properties.<p> <p>Methods - In a placebo-controlled ...
  • Trends in Disability-Free Life Expectancy (DFLE) from 1995 to 2017 in the older Norwegian population by sex and education: The HUNT Study 

    Storeng, Siri Høivik; Øverland, Simon Nygaard; Skirbekk, Vegard; Hopstock, Laila Arnesdatter; Sund, Erik Reidar; Krokstad, Steinar; Strand, Bjørn Heine (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-28)
    Aim: Understanding whether increasing Life Expectancy (LE) translates to improved health and function among older adults is essential, but results are inconclusive. We aimed to estimate trends in Disability-Free Life Expectancy (DFLE) in the older Norwegian population by sex and education from 1995 to 2017.<p> <p>Method: National life table data were combined with cross-sectional data on functional ...
  • A porcine model of hemodialyzer reactions: roles of complement activation and rinsing back of extracorporeal blood 

    Pethő, Ákos; Piecha, Dorothea; Mészáros, Tamás; Urbanics, Rudolf; Moore, Christoph; Canaud, Bernard; Mollnes, Tom Eirik; Steppan, Sonja; Szénási, Gábor; Szebeni, János; Dézsi, László (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-09)
    Hemodialysis reactions (HDRs) resemble complement-activation-related pseudoallergy (CARPA) to certain i.v. drugs, for which pigs provide a sensitive model. On this basis, to better understand the mechanism of human HDRs, we subjected pigs to hemodialysis using polysulfone (FX CorDiax 40, Fresenius) or cellulose triacetate (SureFlux-15UX, Nipro) dialyzers, or Dialysis exchange-set without membranes, ...
  • Inspiratory crackles-early and late-revisited: identifying COPD by crackle characteristics 

    Melbye, Hasse; Aviles Solis, Juan Carlos; Jacome, Cristina; Pasterkamp, Hans (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-05)
    Background The significance of pulmonary crackles, by their timing during inspiration, was described by Nath and Capel in 1974, with early crackles associated with bronchial obstruction and late crackles with restrictive defects. Crackles are also described as ‘fine’ or ‘coarse’. We aimed to evaluate the usefulness of crackle characteristics in the diagnosis of chronic obstructive pulmonary disease ...
  • Salmon louse infestation levels on sea trout can be predicted from a hydrodynamic lice dispersal model 

    Bøhn, Thomas; Nilsen, Rune; Gjelland, Karl Øystein; Biuw, Martin; Primicerio, Raul; Karlsen, Ørjan; Serra Llinares, Rosa Maria (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-13)
    1. The abundance of the parasitic salmon louse has increased with the growth in aquaculture of salmonids in open net pens. This represents a threat to wild salmonid populations as well as a key limiting factor for salmon farming. The Norwegian ‘traffic light’ management system for salmon farming aims to increase aquaculture production while securing sustainable wild salmonid populations. However, ...
  • Zinc-Chelating Compounds as Inhibitors of Human and Bacterial Zinc Metalloproteases 

    Rahman, Fatema; Wushur, Imin; Malla, Nabin; Åstrand, Ove Alexander Høgmoen; Rongved, Pål; Winberg, Jan-Olof; Sylte, Ingebrigt (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-22)
    Inhibition of bacterial virulence is believed to be a new treatment option for bacterial infections. In the present study, we tested dipicolylamine (DPA), tripicolylamine (TPA), tris pyridine ethylene diamine (TPED), pyridine and thiophene derivatives as putative inhibitors of the bacterial virulence factors thermolysin (TLN), pseudolysin (PLN) and aureolysin (ALN) and the human zinc metalloproteases, ...
  • Dysleksi: Tidlige risikomarkører for dysleksi 

    Riise, Sølvi Grønning (Master thesis; Mastergradsoppgave, 2021-12-15)
    The purpose of this master's thesis was to investigate whether or not students who were identified with poor literacy skills at 3rd grade, displayed poor literacy skills at the start of 1st grade and in 2nd grade. The theoretical framework for the master's thesis is the prevailing etiological model for dyslexia, namely the Multiple Deficit Model (MDM). It suggests that dyslexia (and other developmental ...
  • Management of patients with metastatic renal cell cancer and bone metastases 

    Nieder, Carsten; Dalhaug, Astrid; Pawinski, Adam (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-28)
    Background/Aim: Previous research has suggested that patients with metastatic renal cell cancer (mRCC) and bone metastases have a poorer prognosis compared to their counterparts with no skeletal involvement. Therefore, we analyzed the management and outcomes of such patients in our center. Patients and Methods: We performed a retrospective study of 35 consecutive patients who received systemic ...
  • On the Use of Time Series Kernel and Dimensionality Reduction to Identify the Acquisition of Antimicrobial Multidrug Resistance in the Intensive Care Unit 

    Escudero-Arnanz, Oscar; Rodríguez-Álvarez, Joaquín; Mikalsen, Karl Øyvind; Jenssen, Robert; Soguero-Ruiz, Cristina (Conference object; Konferansebidrag, 2021)
    The acquisition of Antimicrobial Multidrug Resistance (AMR) in patients admitted to the Intensive Care Units (ICU) is a major global concern. This study analyses data in the form of multivariate time series (MTS) from 3476 patients recorded at the ICU of University Hospital of Fuenlabrada (Madrid) from 2004 to 2020. 18% of the patients acquired AMR during their stay in the ICU. The goal of ...
  • Trends in initiation of hormonal contraceptive methods among teenagers born between 1989 and 1997 in Norway and the United States 

    Ahrens, Katherrine; Skjeldestad, Finn Egil (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-28)
    Objective - To assess initiation of hormonal contraception among women aged 15-19 in the US and Norway by birth cohort.<p> <p>Study design - We used population-based survey (US) and administrative (Norway) data to estimate the cumulative probability of age at first use of hormonal contraception for female residents born between 1989 and 1997 in 3-year birth cohorts. Differences between countries ...
  • Acupuncture used as a method of peripheral nerve stimulation in chronic prostatitis: A case study 

    Hervik, Jill Angela; Stub, Trine (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-10)
    Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is defined as chronic pelvic pain lasting for at least 3 months, often associated with lower urinary tract symptoms and/or sexual dysfunction [1]. Prostatitis is a common condition, with 35–50% of men affected by symptoms suggesting prostatitis during their lifetime. It is associated with negative psychological effects and substantial health ...
  • ERK3 regulates TDP2-mediated DNA damage response and chemoresistance in lung cancer cells 

    Bian, Ka; Muppani, Naveen Reddy; Elkhadragy, Lobna; Wang, Wei; Zhang, Cheng; Chen, Tenghui; Jung, Sungyun; Seternes, Ole Morten; Long, Weiwen (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12-19)
    Posttranslational modifications (PTMs), such as phosphorylation and ubiquitination, play critical regulatory roles in the assembly of DNA damage response proteins on the DNA damage site and their activities in DNA damage repair. Tyrosyl DNA phosphodiesterase 2 (TDP2) repairs Topoisomerase 2 (Top2)-linked DNA damage, thereby protecting cancer cells against Top2 inhibitors-induced growth inhibition ...
  • Hemostatic factors, inflammatory markers, and risk of incident venous thromboembolism: The Multi-Ethnic Study of Atherosclerosis 

    Evensen, Line Holtet; Folsom, Aaron R.; Pankow, James S.; Hansen, John-Bjarne; Allison, Matthew; Cushman, Mary; Lutsey, Pamela L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-27)
    Background - Several hemostatic factors and inflammatory markers are associated with the risk of incident venous thromboembolism (VTE), however, most existing data are from case-control studies in Caucasian populations.<p> <p>Objectives - We aimed to prospectively confirm previous findings and explore less studied biomarkers in relation to VTE risk in a multi-racial/multi-ethnic cohort.<p> <p>Methods ...
  • Prognostic Impact of Resection Margin Status in Distal Pancreatectomy for Ductal Adenocarcinoma 

    Sahakyan, Mushegh A.; Verbeke, Caroline S.; Tholfsen, Tore; Ignjatovic, Dejan; Kleive, Dyre; Buanes, Trond; Lassen, Kristoffer; Røsok, Bård I.; Labori, Knut Jørgen; Edwin, Bjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-22)
    Background. Resection margin status is considered one of the few surgeon-controlled parameters affecting prognosis in pancreatic ductal adenocarcinoma (PDAC). While studies mostly focus on resection margins in pancreatoduodenectomy, little is known about their role in distal pancreatectomy (DP). This study aimed to investigate resection margins in DP for PDAC.<p> <p>Methods. Patients who ...
  • Chronic iron deficiency and anaemia were highly prevalent in a population-based longitudinal study among adolescent girls 

    Stabell, Niklas; Averina, Maria; Flægstad, Trond (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-01)
    <b>Aim:</b> The combination of iron deficiency and anaemia is a major health problem, and adolescents are an at- risk group. The main aim of this study was to explore the mag-nitude of these conditions among adolescents aged 15–19 and identify possible as-sociated risk factors. <br><b>Methods:</b> This population- based longitudinal study of adolescents in North Norway was conducted in 2010–2011, ...
  • Mitigating the environmental impact of NSAIDs - physiotherapy as a contribution to one health and the SDGs 

    Banerjee, Srishti; Maric (PhD), Filip (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-27)
    Non-steroidal anti-inflammatory drugs (NSAIDs) continue to be amongst the most frequently used pharmaceutical treatments for mild to moderate musculoskeletal pain globally. In this short communication, we continue to expand the growing field of environmental physiotherapy by tracing NSAIDs journey through aquatic ecosystems, and the potential of physiotherapy to mitigate these negative environmental ...
  • Surgery for Degenerative Cervical Myelopathy: A Nationwide Registry-Based Observational Study With Patient-Reported Outcomes 

    Gulati, Sasha; Vangen-Lønne, Vetle; Nygaard, Øystein Petter; Gulati, Agnete Malm; Hammer, Tommy; Johansen, Tonje Okkenhaug; Peul, Wilco C.; Salvesen, Øyvind; Solberg, Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-29)
    Background: Indications and optimal timing for surgical treatment of degenerative cervical myelopathy (DCM) remain unclear, and data from daily clinical practice are warranted.<p> <p>Objective: To investigate clinical outcomes following decompressive surgery for DCM. Methods: Data were obtained from the Norwegian Registry for Spine Surgery. The primary outcome was change in the neck disability index ...
  • Comparative Genomics Reveals Factors Associated with Phenotypic Expression of Wolbachia 

    Baião, GC; Janice, Jessin; Galinou, M; Klasson, Lisa (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-18)
    Wolbachia is a widespread, vertically transmitted bacterial endosymbiont known for manipulating arthropod reproduction. Its most common form of reproductive manipulation is cytoplasmic incompatibility (CI), observed when a modification in the male sperm leads to embryonic lethality unless a compatible rescue factor is present in the female egg. CI attracts scientific attention due to its implications ...
  • Multifunctional Nanofibrous Dressing with Antimicrobial and Anti-Inflammatory Properties Prepared by Needle-Free Electrospinning 

    Schulte Werning, Laura; Murugaiah, Anjanah; Singh, Bhupender; Johannessen, Mona; Engstad, Rolf Einar; Skalko-Basnet, Natasa; Holsæter, Ann Mari (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-21)
    An active wound dressing should address the main goals in wound treatment, which are improved wound healing and reduced infection rates. We developed novel multifunctional nanofibrous wound dressings with three active ingredients: chloramphenicol (CAM), beta-glucan (βG) and chitosan (CHI), of which βG and CHI are active nanofiber-forming biopolymers isolated from the cell walls of Saccharomyces ...

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