Recent additions

  • Leisure physical exercise and creatine kinase activity. The Tromsø study 

    Bekkelund, Svein Ivar (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-16)
    Creatine kinase (CK) is an enzyme catalyzing energy reaction in muscle cells and has proven to modify cardiovascular risks. The influence of skeletal muscle activity on CK concentrations is a potential study confounder but is mainly reported in connection with sport activities. This study investigated the association between leisure physical exercise and CK and estimated the effect of physical ...
  • Acquiring sub-efficient and efficient variants of novel means by integrating information from multiple social models in preschoolers 

    Altınok, Nazlı; Hernik, Mikołaj; Király, Ildikó; Gergely, György (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-08)
    Sub-efficient action routines often represent culture-specific conventional forms of actions that belong to the repertoire of cultural knowledge shared by a social group. Children readily acquire such sub-efficient routines from social demonstrations and often preserve them in their action repertoire despite encountering more efficient alternatives. This suggests that they can treat sub-efficient ...
  • Management strategies for children with COVID-19: ESPR practical recommendations 

    Raissaki, Maria; Shelmerdine, Susan; Damasio, Beatrice; Toso, Seema; Kvist, Ola; Lovrenski, Jovan; Hirsch, Franz Wolfgang; Görkem, Süreyya Burcu; Paterson, Anne; Arthurs, Owen J.; Rossi, Andrea; van Schuppen, Joost; Petit, Philippe; Argyropoulou, Maria I.; Offiah, Amaka C.; Rosendahl, Karen; Caro-Domínguez, Pablo (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-03)
    During the outbreak of the COVID-19 pandemic, guidelines have been issued by international, national and local authorities to address management and the need for preparedness. Children with COVID-19 differ from adults in that they are less often and less severely affected. Additional precautions required in the management of children address their increased radiosensitivity, need for accompanying ...
  • BK polyomavirus evades innate immune sensing by disrupting the mitochondrial network and promotes mitophagy 

    Manzetti, Julia; Weissbach, Fabian H.; Graf, Fabrice E.; Unterstab, Gunhild; Wernli, Marion; Hopfer, Helmut; Drachenberg, Cinthia B.; Rinaldo, Christine Hanssen; Hirsch, Hans H. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-10)
    Immune escape contributes to viral persistence, yet little is known about human polyomaviruses. BK-polyomavirus (BKPyV) asymptomatically infects 90% of humans but causes premature allograft failure in kidney transplant patients. Despite virus-specific T cells and neutralizing antibodies, BKPyV persists in kidneys and evades immune control as evidenced by urinary shedding in immunocompetent individuals. ...
  • Healthy lifestyle and the risk of lymphoma in the European Prospective Investigation into Cancer and Nutrition study 

    Naudin, Sabine; Margalef, Marta Solans; Saberi Hosnijeh, Fatemeh; Nieters, Alexandra; Kyrø, Cecilie; Tjønneland, Anne; Dahm, Christina C.; Overvad, Kim; Mahamat-Saleh, Yahya; Besson, Caroline; Boutron-Ruault, Marie-Christine; Kühn, Tilman; Canzian, Federico; Schulze, Matthias B.; Peppa, Eleni; Karakatsani, Anna; Trichopoulou, Antonia; Sieri, Sabina; Masala, Giovana; Panico, Salvatore; Tumino, Rosario; Ricceri, Fulvio; Chen, Sairah Lai Fa; Barroso, Leila L.; Huerta, José María; Sánchez, Maria-Jose; Ardanaz, Eva; Menéndez, Virginia; Exezarreta, Pilar Amiano; Spaeth, Florentin; Jerkeman, Mats; Jirstom, Karin; Schmidt, Julie A.; Aune, Dagfinn; Weiderpass, Elisabete; Riboli, Elio; Vermeulen, Roel; Casabonne, Delphine; Gunter, Marc; Brennan, Paul; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-16)
    Limited evidence exists on the role of modifiable lifestyle factors on the risk of lymphoma. In this work, the associations between adherence to healthy lifestyles and risks of Hodgkin lymphoma (HL) and non‐Hodgkin lymphoma (NHL) were evaluated in a large‐scale European prospective cohort. Within the European Prospective Investigation into Cancer and Nutrition (EPIC), 2,999 incident lymphoma cases ...
  • Electronic cigarettes and health with special focus on cardiovascular effects: position paper of the European Association of Preventive Cardiology (EAPC) 

    Kavousi, Maryam; Pisinger, Charlotta; Barthelemy, Jean-Claude; Smedt, Delphine De; Koskinas, Konstantinos; Marques-Vidal, Pedro; Panagiotakos, Demosthenes; Prescott, Eva Bossano; Tiberi, Monica; Vassiliou, Vassilios S; Løchen, Maja-Lisa (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-17)
    Background - Tobacco use is the single largest preventable risk factor for premature death of non-communicable diseases and the second leading cause of cardiovascular disease. In response to the harmful effects of tobacco smoking, the use of electronic cigarettes (e-cigarettes) has emerged and gained significant popularity over the past 15 years. E-cigarettes are promoted as safe alternatives for ...
  • 'You should see a doctor', said the robot: Reflections on a digital diagnostic device in a pandemic age 

    Haase, Christoffer Bjerre; Bearman, Margaret; Brodersen, John; Hoeyer, Klaus; Risør, Torsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-18)
    Aims: In three days at the beginning of the COVID-19 pandemic, the Copenhagen Emergency Medical Services developed a digital diagnostic device. The purpose was to assess and triage potential COVID-19 symptoms and to reduce the number of calls to public health-care helplines. The device was used almost 150,000 times in a few weeks and was described by politicians and administrators as a solution and ...
  • Consumption of Fish and Long-chain n-3 Polyunsaturated Fatty Acids Is Associated With Reduced Risk of Colorectal Cancer in a Large European Cohort 

    Aglago, Elom Kouassivi; Huybrechts, Inge; Murphy, Neil; Casagrande, Corinne; Nicolas, Geneviève; Pischon, Tobias; Fedirko, Veronika; Severi, Gianluca; Boutron-Ruault, Marie-Christine; Fournier, Agnès; Katzke, Verena Andrea; Kühn, Tilman; Olsen, Anja; Tjønneland, Anne; Dahm, Christina C.; Overvad, Kim; Lasheras, Cristina; Agudo, Antonio; Sanchez, Maria-Jose; Amiano, Pilar; Huerta, Jose Maria; Ardanaz, Eva; Perez-Cornago, Aurora; Trichopoulou, Antonia; Karakatsani, Anna; Martimianaki, Georgia; Bueno-De-Mesquita, Bas; May, Anne; Derksen, Jeroen W.G.; Hellstrand, Sophie; Ohlsson, Bodil; Wennberg, Maria; Van Guelpen, Bethany; Skeie, Guri; Brustad, Magritt; Weiderpass, Elisabete; Cross, Amanda J.; Ward, Heather; Riboli, Elio; Norat, Teresa; Chajes, Veronique; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-25)
    Background & Aims - There is an unclear association between intake of fish and long-chain n-3 polyunsaturated fatty acids (n-3 LC-PUFAs) and colorectal cancer (CRC). We examined the association between fish consumption, dietary and circulating levels of n-3 LC-PUFAs, and ratio of n-6:n-3 LC-PUFA with CRC using data from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. ...
  • Female genital self-image in women with and without female genital mutilation/cutting in Jeddah, Saudi Arabia 

    Rouzi, Abdulrahim A.; Berg, Rigmor; Alamoudi, Rana; Alzaban, Faten; Sehlo, Mohammad (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-29)
    Introduction - The consequences of female genital mutilation/cutting (FGM/C) on female genital self-image are not known.<p> <p>Aim - To assess whether women with and without FGM/C differed with regard to female genital self-image.<p> <p>Methods - A survey was administered to a group of women attending the King Abdulaziz University Hospital obstetrics and gynecology clinic from December 2016 ...
  • Combined Influence of Waist and Hip Circumference on Risk of Death in a Large Cohort of European and Australian Adults 

    Cameron, Adrian J.; Romaniuk, Helena; Orellana, Liliana; Dallongeville, Jean; Dobson, Annette J; Drygas, Wojciech; Ferrario, Marco; Ferrieres, Jean; Giampaoli, Simona; Gianfagna, Francesco; Iacoviello, Licia; Jousilahti, Pekka; Kee, Frank; Moitry, Marie; Niiranen, Teemu J; Pajak, Andrzej; Palmieri, Luigi; Palosaari, Tarja; Mannisto, Satu; Tamosiunas, Abdonas; Thorand, Barbara; Toft, Ulla; Vanuzzo, Diego; Salomaa, Veikko; Veronesi, Giovanni; Wilsgaard, Tom; Kuulasmaa, Kari; Söderberg, Stefan (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-30)
    Background - Waist circumference and hip circumference are both strongly associated with risk of death; however, their joint association has rarely been investigated.<p> <p>Methods and Results - The MONICA Risk, Genetics, Archiving, and Monograph (MORGAM) Project was conducted in 30 cohorts from 11 countries; 90 487 men and women, aged 30 to 74 years, predominantly white, with no history of ...
  • A possible effect of montelukast on neurological aging examined by the use of register data 

    Grinde, Bjørn; Schirmer, Henrik; Eggen, Anne Elise; Aigner, Ludwig; Engdahl, Bo Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-09)
    Background - The leukotriene receptor antagonist montelukast has been shown to rejuvenate aged brains in rats; however, data on humans are still scarce. Objective To investigate if montelukast may alleviate degenerative neurological changes using a register data. Setting Norwegian registry data analyses. <p> <p>Method - The present observational study was based on data from the Norwegian Prescription ...
  • Barn og unges medvirkning i barnevernet: en systematisk kartleggingsoversikt 

    Ormstad, Sari Susanna; Hestevik, Christine Hillestad; Munthe-Kaas, Heather Menzies; Blaasvær, Nora; Muller, Ashley Elizabeth; Berg, Rigmor (Research report; Forskningsrapport, 2020)
    Barn har rett til å medvirke i alle saker som vedrører dem. Barne-, ungdoms- og familiedirektoratet (Bufdir) ønsket en oversikt over forskning som har undersøkt barn og unges medvirkning i barnevernet: 1) hvordan barn og unge involveres i barnevernet, 2) barn og unges opplevelser med og preferanser for medvirkning, 3) dilemmaer knyttet til medvirkning, og 4) effektene av medvirkning.<p> <p>Metode ...
  • Serologic markers of Chlamydia trachomatis and other sexually transmitted infections and subsequent ovarian cancer risk: Results from the EPIC cohort 

    Idahl, Annika; Le Cornet, Charlotte; González Maldonado, Sandra; Waterboer, Tim; Bender, Noemi; Tjønneland, Anne; Hansen, Louise; Boutron-Ruault, Marie-Christine; Fournier, Agnès; Kvaskoff, Marina; Boeing, Heiner; Trichopoulou, Antonia; Valanou, Elissavet; Peppa, Eleni; Palli, Domenico; Agnoli, Claudia; Mattiello, Amalia; Tumino, Rosaria; Sacerdote, Carlotta; Onland-Moret, N. Charlotte; Gram, Inger Torhild; Weiderpass, Elisabete; Quirós, J. Ramón; Duell, Eric J.; Sánchez, Maria-Jose; Chirlaque, Maria-Dolores; Barricarte, Aurelio; Gil, Leire; Brändstedt, Jenny; Riesbeck, Kristian; Lundin, Eva; Khaw, Kay-Tee; Perez-Cornago, Aurora; Gunter, Marc; Dossus, Laure; Kaaks, Rudolf; Fortner, Renée T. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-03)
    A substantial proportion of epithelial ovarian cancer (EOC) arises in the fallopian tube and other epithelia of the upper genital tract; these epithelia may incur damage and neoplastic transformation after sexually transmitted infections (STI) and pelvic inflammatory disease. We investigated the hypothesis that past STI infection, particularly Chlamydia trachomatis, is associated with higher EOC ...
  • Smoking-Related Risks of Colorectal Cancer by Anatomical Subsite and Sex 

    Gram, Inger Torhild; Park, Song-Yi; Wilkens, Lynne R; Haiman, Christopher A.; Le Marchand, Loïc (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-23)
    The purpose of this study was to examine whether the increased risk of colorectal cancer due to cigarette smoking differed by anatomical subsite or sex. We analyzed data from 188,052 participants aged 45–75 years (45% men) who were enrolled in the Multiethnic Cohort Study in 1993–1996. During a mean follow-up period of 16.7 years, we identified 4,879 incident cases of invasive colorectal adenocarcinoma. ...
  • Grain and dietary fiber intake and bladder cancer risk: a pooled analysis of prospective cohort studies 

    Yu, Evan Y W; Wesselius, Anke; Mehrkanoon, Siamak; Brinkman, Maree; van den Brandt, Piet; White, Emily; Weiderpass, Elisabete; Le Calvez-Kelm, Florence; Gunter, Marc; Huybrechts, Inge; Liedberg, Fredrik; Skeie, Guri; Tjonneland, Anne; Riboli, Elio; Giles, Graham; Milne, Roger L; Zeegers, Maurice P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-10)
    Background - Higher intakes of whole grains and dietary fiber have been associated with lower risk of insulin resistance, hyperinsulinemia, and inflammation, which are known predisposing factors for cancer.<p> <p>Objectives - Because the evidence of association with bladder cancer (BC) is limited, we aimed to assess associations with BC risk for intakes of whole grains, refined grains, and dietary ...
  • Comparing Calculated Nutrient Intakes Using Different Food Composition Databases: Results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Cohort 

    Van Puyvelde, Heleen; Perez-Cornago, Aurora; Casagrande, Corinne; Nicolas, Geneviève; Versele, Vickà; Skeie, Guri; Schulze, Matthias B.; Johansson, Ingegerd; Huerta, José María; Oliverio, Andreina; Ricceri, Fulvio; Halkjær, Jytte; Etxezarreta, Pilar Amiano; Van Herck, Koen; Weiderpass, Elisabete; Gunter, Marc J.; Huybrechts, Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-23)
    This study aimed to compare calculated nutrient intakes from two different food composition databases using data from the European prospective investigation into cancer and nutrition (EPIC) cohort. Dietary intake data of the EPIC cohort was recently matched to 150 food components from the U.S. nutrient database (USNDB). Twenty-eight of these nutrients were already included in the EPIC nutrient ...
  • Demographic variation in fit note receipt and long-term conditions in south London 

    Dorrington, Sarah; Carr, Ewan; Stevelink, Sharon A. M.; Dregan, Alexandru; Whitney, David; Durbaba, Stevo; Ashworth, Mark; Mykletun, Arnstein; Broadbent, Matthew; Madan, Ira; Hatch, Stephani; Hotopf, Matthew (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-24)
    Objectives - Introduced in the UK in 2010, the fit note was designed to address the problem of long-term sickness absence. We explored (1) associations between demographic variables and fit note receipt, ‘maybe fit’ use and long-term conditions, (2) whether individuals with long-term conditions receive more fit notes and are more likely to have the ‘maybe fit’ option selected and (3) whether long-term ...
  • C-reactive protein-guided antibiotic prescribing for COPD exacerbations: A qualitative evaluation 

    Phillips, Rhiannon; Stanton, H.; Singh-Mehta, A.; Gillespie, David; Bates, Janine; Gal, Micaela; Thomas-Jones, Emma; Lowe, Rachel; Hood, Kerenza; Llor, Carl; Melbye, Hasse; Cals, Jochen; White, Patrick; Butler, Christopher C.; Francis, Nick (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-25)
    Background - Antibiotics are prescribed to >70% of patients presenting in primary care with an acute exacerbation of chronic obstructive pulmonary disease (AECOPD). The PACE randomised controlled trial found that a C-reactive protein point-of-care test (CRP-POCT) management strategy for AECOPD in primary care resulted in a 20% reduction in patient-reported antibiotic consumption over 4 weeks.<p> <p>Aim ...
  • Metachronous Contralateral Testicular Cancer in the Cisplatin Era: A Population-Based Cohort Study 

    Hellesnes, Ragnhild; Myklebust, Tor Åge; Bremnes, Roy M.; Karlsdottir, Åsa; Kvammen, Øivind; Negaard, Helene Francisca Stigter; Tandstad, Torgrim; Wilsgaard, Tom; Fosså, Sophie Dorothea; Haugnes, Hege Sagstuen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-23)
    PURPOSE - It is hypothesized that cisplatin-based chemotherapy (CBCT) reduces the occurrence of metachronous contralateral (second) germ cell testicular cancer (TC). However, studies including treatment details are lacking. The aim of this study was to assess the second TC risk, emphasizing the impact of previous TC treatment.<p> <p>PATIENTS AND METHODS - Based on the Cancer Registry of Norway, ...
  • Prognostic value of absolute quantification of mutated KRAS in circulating tumour DNA in lung adenocarcinoma patients prior to therapy 

    Wahl, Sissel Gyrid Freim; Hong, Yan Dai; Emdal, Elisabeth Fritzke; Ottestad, Anine Larsen; Dale, Vibeke Grotnes; Richardsen, Elin; Halvorsen, Tarje Onsøien; Grønberg, Bjørn Henning (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-27)
    Droplet digital polymerase chain reaction (ddPCR) is a highly sensitive and accurate method for quantification of nucleic acid sequences. We used absolute quantification of mutated v‐Ki‐ras2 Kirsten rat sarcoma viral oncogene homology gene (KRAS) by ddPCR to investigate the prognostic role of mutated KRAS in patients with KRAS‐mutated lung adenocarcinomas. Pre‐treatment plasma samples from 60 patients ...

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