Recent additions

  • Systematisk oversikt over sykestueforskning med vekt på kvalitet, økonomi og pasientforløp 

    Nilsen, Karoline Damsgård (Master thesis; Mastergradsoppgave, 2017-09-17)
    Introduksjon: Samhandlingsreformen og den nye helse- og omsorgstjenesteloven påla alle kommuner å opprette øyeblikkelig hjelp døgntilbud fra 1.1.2016. Intermediærenheter som sykestuer har de siste tiårene fått økende fokus både i Norge og i utlandet. Målet med denne oppgaven er å lage en systematisk oversikt over forskningslitteratur som omhandler sykestuer med vekt på kvalitet, økonomi og ...
  • The use of commercial ELISA kits in measuring CA6 concentration of saliva 

    Machlik, Edit; Woll, Emilie Elise (Mastergradsoppgave; Master thesis, 2021-05-20)
    Introduction: Carbonic anhydrase 6 (CA6) is the only secreted member of the carbonic anhydrase enzyme family. This enzyme catalyzes the reversible hydration of carbon dioxide: CO2 + H2O ⇔ H+ + HCO3-. The dehydration reaction contributes to net acidification in several tissues and biological fluids. Salivary CA6 attaches to the enamel and predisposes to caries probably by acidifying the dental biofilm ...
  • Selecting stimulation intensity in repetitive transcranial magnetic stimulation studies: A systematic review between 1991 and 2020 

    Turi, Zsolt; Lenz, Maximilian; Paulus, Walter; Mittner, Matthias; Vlachos, Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-22)
    Repetitive transcranial magnetic stimulation (rTMS) is an increasingly used, non-invasive brain stimulation technique in neuroscience research and clinical practice with a broad spectrum of suggested applications. Among other parameters, the choice of stimulus intensity and intracranial electric field strength substantially impacts rTMS outcome. This review provides a systematic overview of the ...
  • Advanced methods in reproductive medicine: Application of optical nanoscopy, artificial intelligence-assisted quantitative phase microscopy and mitochondrial DNA copy numbers to assess human sperm cells 

    Popova, Daria (Doctoral thesis; Doktorgradsavhandling, 2021-10-22)
    Declined fertility rate and population is a matter of serious concern, especially in the developed nations. Assisted Reproductive Technologies (ART), including in vitro fertilization (IVF), have provided great hope for infertility treatment and maintaining population growth and social structure. With the help of ART, more than 8 million babies have already been born so far. Despite the worldwide ...
  • Oral health and use of dental services in different stages of adulthood in Norway: a cross sectional study 

    Hadler-Olsen, Elin Synnøve; Jönsson, Birgitta (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-13)
    <i>Background</i> - Socioeconomic status and oral health care habits may change throughout adult life. This calls for age-stratified analyses of oral health in the adult population to uncover differences that could be of importance for organizing adequate oral health care services. The aim of the present study was to describe self-reported oral health in different age groups in a general adult ...
  • Validating Acute Myocardial Infarction Diagnoses in National Health Registers for Use as Endpoint in Research: The Tromsø Study 

    Varmdal, Torunn; Mathiesen, Ellisiv B.; Wilsgaard, Tom; Njølstad, Inger; Nyrnes, Audhild; Grimsgaard, Sameline; Bønaa, Kaare Harald; Mannsverk, Jan; Løchen, Maja-Lisa (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-03)
    <i>Purpose</i>: To assess whether acute myocardial infarction (MI) diagnoses in national health registers are sufficiently correct and complete to replace manual collection of endpoint data for a population-based, epidemiological study.<br><br> <i>Patients and Methods</i>: Using the Tromsø Study Cardiovascular Disease Register for 2013– 2014 as gold standard, we calculated correctness (defined ...
  • Symptoms and signs of colorectal cancer, with differences between proximal and distal colon cancer: a prospective cohort study of diagnostic accuracy in primary care 

    Holtedahl, Knut; Borgquist, Lars; Donker, Gé A.; Buntinx, Frank; Weller, David; Campbell, Christine; Månsson, Jörgen; Hammersley, Victoria; Braaten, Tonje; Parajuli, Ranjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-08)
    <i>Background</i> - In an abdominal symptom study in primary care in six European countries, 511 cases of cancer were recorded prospectively among 61,802 patients 16 years and older in Norway, Denmark, Sweden, Netherlands, Belgium and Scotland. Colorectal cancer is one of the main types of cancer associated with abdominal symptoms; hence, an in-depth subgroup analysis of the 94 colorectal cancers ...
  • Risk of cervical intraepithelial neoplasia grade 3 or higher (CIN3+) among women with HPV-test in 1990–1992, a 30-year follow-up study 

    Riibe, Marit Østlyngen; Sørbye, Sveinung Wergeland; Simonsen, Gunnar Skov; Sundsfjord, Arnfinn; Ekgren, Josef; Maltau, Jan Martin (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-22)
    <i>Background/objective</i> - Having a 30-year follow-up of a cohort of women tested for HPV is a unique opportunity to further study long-term risk of CIN3+. The study objective was to compare HPV status at baseline with the risk of CIN3+ in the follow-up period of 30 years.<br><br> <i>Methods</i> - All women (n = 642) referred to the HPV outpatient clinic at the University Hospital of North ...
  • Ginseng for Erectile Dysfunction: A Cochrane Systematic Review 

    Lee, Hye Won; Lee, Myeong Soo; Kim, Tae-Hun; Alræk, Terje; Zaslawski, Chris; Kim, Jong Wook; Moon, Du Geon (Journal article; Tidsskriftartikkel; Peer reviewed, 2021)
    The objectives of this study were to assess the effects of ginseng on erectile dysfunction. We searched multiple electronic databases from their inceptions to 30 January 2021 without restrictions by language. We included randomized or quasirandomized controlled trials that evaluated the use of any type of ginseng as a treatment for erectile dysfunction compared to placebo or conventional treatment. ...
  • Development of 8f-labeled radiotracers for pet imaging of the adenosine a2a receptor: Synthesis, radiolabeling and preliminary biological evaluation 

    Lai, Thu Hang; Schröder, Susann; Toussaint, Magali; Dukić-Stefanović, Sladjana; Kranz, Mathias; Ludwig, Friedrich-Alexander; Fischer, Steffen; Steinbach, Jörg; Deuther-Conrad, Winnie; Brust, Peter; Moldovan, Rareş-Petru (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-25)
    The adenosine A<sub>2A</sub> receptor (A<sub>2A</sub>R) represents a potential therapeutic target for neurodegenerative diseases. Aiming at the development of a positron emission tomography (PET) radiotracer to monitor changes of receptor density and/or occupancy during the A<sub>2A</sub>R-tailored therapy, we designed a library of fluorinated analogs based on a recently published lead compound ...
  • Validity and responsiveness of EQ-5D-5L and SF-6D in patients with health complaints attributed to their amalgam fillings: a prospective cohort study of patients undergoing amalgam removal 

    Lamu, Admassu N.; Björkman, Lars; Hamre, Harald Johan; Alræk, Terje; Musial, Frauke; Robberstad, Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-17)
    <i>Background</i> - Evidence of health utility changes in patients who suffer from longstanding health complaints attributed to dental amalgam fillings are limited. The change in health utility outcomes enables calculating quality-adjusted life-year (QALY) and facilitates the comparison with other health conditions. The purpose of this study was to estimate the validity and responsiveness of the ...
  • Multiscale and Multimodal Optical Imaging of the Ultrastructure of Human Liver Biopsies 

    Kong, Cihang; Bobe, Stefanie; Pilger, Christian; Lachetta, Mario; Øie, Cristina Ionica; Kirschnick, Nils; Mönkemöller, Viola; Hübner, Wolfgang; Förster, Christine; Schuttpelz, Mark; Kiefer, Friedemann; Huser, Thomas; Schulte am Esch, Jan (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-17)
    The liver as the largest organ in the human body is composed of a complex macroscopic and microscopic architecture that supports its indispensable function to maintain physiological homeostasis. Optical imaging of the human liver is particularly challenging because of the need to cover length scales across 7 orders of magnitude (from the centimeter scale to the nanometer scale) in order to fully ...
  • Agenda navigation in consultations covering multiple topics. A qualitative case study from general practice 

    Guassora, Ann Dorrit; Johansen, May-Lill; Malterud, Kirsti (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-26)
    Objective - To explore how agenda navigation may be accomplished underway in consultations covering multiple topics, we identified and analyzed one GP’s communicative strategies.<p> <p>Design, setting, and subjects - A qualitative observational case study with linguistic microanalysis of an exemplary consultation between a female patient with diabetes and her male GP. We used speech act theory ...
  • The prognostic effect of KRAS mutations in non-small cell lung carcinoma revisited: A norwegian multicentre study 

    Wahl, Sissel Gyrid Freim; Hong, Yan Dai; Emdal, Elisabeth Fritzke; Berg, Thomas; Halvorsen, Tarje Onsøien; Ottestad, Anine Larsen; Lund-Iversen, Marius; Brustugun, Odd; Førde, Dagny; Paulsen, Erna-Elise; Donnem, Tom; Andersen, Sigve; Grønberg, Bjørn Henning; Richardsen, Elin (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-26)
    Background: due to emerging therapeutics targeting KRAS G12C and previous reports with conflicting results regarding the prognostic impact of KRAS and KRAS G12C in non-small cell lung cancer (NSCLC), we aimed to investigate the frequency of KRAS mutations and their associations with clinical characteristics and outcome. Since mutation subtypes have different preferences for downstream pathways, we ...
  • Dental caries in children and adolescents with juvenile idiopathic arthritis and controls: a multilevel analysis 

    Gil, Elisabeth G.; Åstrøm, Anne-Kristine N; Lie, Stein Atle; Rygg, Marite; Fischer, Johannes; Rosén, Annika; Bletsa, Athanasia; Luukko, Keijo; Shi, Xie-Qi; Halbig, Josefine; Frid, Paula; Cetrelli, Lena Elisabet; Tylleskär, Karin; Rosendahl, Karen; Skeie, Marit Slåttelid (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-25)
    Background - Optimal utilization of dental caries data is crucial in epidemiological research of individuals with juvenile idiopathic arthritis (JIA). The aims were to: explore whether caries is more prevalent among children and adolescents with JIA compared to controls; examine presence of caries according to JIA group, socio-behavioral and intraoral characteristics, and the extent to which ...
  • Exploring Klebsiella pneumoniae in Healthy Poultry Reveals High Genetic Diversity, Good Biofilm-Forming Abilities and Higher Prevalence in Turkeys Than Broilers 

    Franklin-Alming, Fiona; Kaspersen, Håkon; Hetland, Marit A. K.; Bakksjø, Ragna-Johanne; Nesse, Live L.; Leangapichart, Thongpan; Löhr, Iren Høyland; Telke, Amar; Sunde, Marianne (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-07)
    Klebsiella pneumoniae is a well-studied human pathogen for which antimicrobial resistant and hypervirulent clones have emerged globally. K. pneumoniae is also present in a variety of environmental niches, but currently there is a lack of knowledge on the occurrence and characteristics of K. pneumoniae from non-human sources. Certain environmental niches, e.g., animals, may be associated with high ...
  • Reciprocal transactivation of Merkel cell polyomavirus and high-risk human papillomavirus promoter activities and increased expression of their oncoproteins 

    Rasheed, Kashif; Sveinbjørnsson, Baldur; Moens, Ugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-03)
    <i>Background</i> - Approximately 15% of human cancers are attributed to viruses. Numerous studies have shown that high-risk human polyomaviruses (HR-HPV) and Merkel cell polyomavirus (MCPyV) are two human tumor viruses associated with anogenetal and oropharyngeal cancers, and with Merkel cell carcinoma, respectively. MCPyV has been found in HR-HPV positive anogenetal and oropharyngeal tumors, ...
  • Identifying Resilience Factors of Distress and Paranoia During the COVID-19 Outbreak in Five Countries 

    Mækelæ, Martin Jensen; Reggev, Niv; Defelipe, Renata P.; Dutra, Natalia; Tamayo, Ricardo; Klevjer, Kristoffer; Pfuhl, Gerit (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-10)
    The ongoing COVID-19 pandemic outbreak has affected all countries with more than 100 million confirmed cases and over 2.1 million casualties by the end of January 2021 worldwide. A prolonged pandemic can harm global levels of optimism, regularity, and sense of meaning and belonging, yielding adverse effects on individuals' mental health as represented by worry, paranoia, and distress. Here we studied ...
  • Parent reports of children's emotional and behavioral problems in a low- and middleincome country (LMIC): An epidemiological study of Nepali schoolchildren 

    Ma, Jasmine; Mahat, Pashupati; Brøndbo, Per Håkan; Handegård, Bjørn H.; Kvernmo, Siv; Javo, Anne Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-03)
    <i>Background</i> - As epidemiological data on child mental health in low- and middle-income countries are limited, a large-scale survey was undertaken to estimate the prevalence and amount of child emotional and behavioral problems (EBP) in Nepal as reported by the parents.<br><br> <i>Methods</i> - 3820 schoolchildren aged 6–18 years were selected from 16 districts of the three geographical ...
  • Religion and Health in Arctic Norway–the association of religious and spiritual factors with suicidal behaviour in a mixed Sámi and Norwegian adult population - The SAMINOR 2 Questionnaire Survey 

    Kiærbech, Henrik; Silviken, Anne; Lorem, Geir F; Kristiansen, Roald E; Spein, Anna Rita (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-12)
    Given the higher suicide rates among the adult population in the northernmost part of Norway and some unfavourable psychosocial outcomes associated with the Laestadian revival movement in this region, it is reasonable to investigate the relationship between religiosity/spirituality and suicidal behaviour in this context. This study used cross-sectional data from the population-based SAMINOR 2 ...

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