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Risiko for fatale og ikke-fatale skader hos voksne i Norge - en retrospektiv registerstudie på populasjonsnivå av traumer i Norge
(Master thesis; Mastergradsoppgave, 2020-07-19)Formål Det er tidligere vist høyere risiko for død i rurale områder i Norge (2, 3). Paradoksalt er det funnet lavere prevalens av alvorlige, ikke-fatale skader ruralt (3). Vi undersøkte om den økte risikoen for død og lavere prevalens av ikke-fatale skader også gjelder for perioden 2002- 2016, når man bruker Statistisk Sentralitetsbyrås (SSB) sentralitetsindeks som mål for ruralitet. Materiale ... -
Self-reported medication use among coronary heart disease patients showed high validity compared with dispensing data
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-24)<i>Objective</i> - To validate self-reported use of medications for secondary prevention of coronary heart disease (CHD) in a population-based health study by comparing self-report with pharmacy dispensing data, and explore different methods for defining medication use in prescription databases.<br><br> <i>Study design and setting</i> - Self-reported medication use among participants with CHD ... -
Persistent level of mental distress in PTSD patients is not reflected in cytokine levels 1 year after the treatment
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-27)<i>Objective</i>: Cross-sectional data show that post-traumatic stress disorder (PTSD) patients often have increased levels of circulating inflammatory markers. There is, however, still a paucity of longitudinal studies with long follow-up times on levels of cytokines in such patients. The current study assesses patients with and without PTSD diagnosis 1 year after discharge from inpatient ... -
Kunnskapsoppsummering og klassifisering av tiltaket Mitt valg! Ungdomsskole-versjonen (1. utg)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-09)<i>BAKGRUNN</i> - MITT VALG er en norsk tilpasset versjon av det universelt forebyggende undervisningsprogrammet Lions Quest som er utviklet i USA. MITT VALG er beskrevet som et livsmestringsprogram med fokus på sosial og emosjonell læring, psykisk helse, kritisk tenkning og faglig utvikling. Denne oppsummeringen tar for seg opplæringsprogrammet MITT VALG for ungdomskolen. MITT VALG eies av Stiftelsen ... -
Working for the Best or Bracing for the Worst? Approach and Avoidance Motivation in Planning
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-11)Even though planning is generally helpful in goal pursuit, people do not always choose to plan. The inclination to plan might depend on whether we focus on what we seek to approach or what we seek to avoid. In two pre-registered experiments, we tested the relative effect of approach versus avoidance motivation on willingness to plan (total <i>N</i>=1349). With outcome framing as the experimental ... -
Blood Pressure Treatment in Kidney Transplant Recipients - Can We Improve?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-25)<i>Background</i> - Hypertension in kidney transplant (KTx) recipients is common, affecting both patient and graft survival. Annual data from the Norwegian Renal Registry reveal that <50% of adult (>18 y) KTx recipients reach target blood pressure (BP) ≤130/80 mm Hg. The aim of this study was to identify the determinants of failure to achieve BP control.<br><br> <i>Methods</i> - In conjunction ... -
Nephronectin as a matrix effector in cancer
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-25)The extracellular matrix protein nephronectin plays an important regulatory role during embryonic development, controlling renal organogenesis through integrin α8β1 association. Nephronectin has three main domains: five N-terminal epidermal growth factor-like domains, a linker region harbouring two integrin-binding motifs (RGD and LFEIFEIER), and a C-terminal MAM domain. In this review, we look into ... -
Prevalence, diversity and transferability of the Tn916-Tn1545 family ICE in oral streptococci
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-15)<i>Background</i>: The Tn<i>916</i>-Tn<i>1545</i> family of Integrative Conjugative Elements (ICE) are mobile genetic elements (MGEs) that play a role in the spread of antibiotic resistance genes. The Tn<i>916</i> harbors the tetracycline resistance gene <i>tet</i>(M) and it has been reported in various bacterial species. The increase in the levels of tetracycline resistance among oral streptococci ... -
Patient experiences of waiting times in standardised cancer patient pathways in Norway – a qualitative interview study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-05)Objective - Standardised cancer patient pathways (CPP) are implemented within cancer care with an aim to ensure standardised waiting times for diagnosis and treatment. This article investigates how patients in Norway experience waiting times within a CPP.<p> <p>Methods - Qualitative semi-structured interviews with 19 patients who had been through CPP for breast cancer, prostate cancer or malignant ... -
How common is substandard obstetric care in adverse events of birth asphyxia, shoulder dystocia and postpartum hemorrhage? Findings from an external inspection of Norwegian maternity units
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-15)Introduction - The Norwegian Board of Health Supervision inspects healthcare institutions to ensure safety and quality of health and welfare services. A planned inspection of 12 maternity units aimed to investigate the practice of obstetric care in the case of birth asphyxia, shoulder dystocia and severe postpartum hemorrhage.<p> <p>Material and methods - The inspection was carried out at two ... -
Distracting stimuli evoke ventral tegmental area responses in rats during ongoing saccharin consumption
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-11)Disruptions in attention, salience and increased distractibility are implicated in multiple psychiatric conditions. The ventral tegmental area (VTA) is a potential site for converging information about external stimuli and internal states to be integrated and guide adaptive behaviours. Given the dual role of dopamine signals in both driving ongoing behaviours (e.g., feeding) and monitoring salient ... -
Time trends of perfluoroalkyl substances in blood in 30-year old Norwegian men and women in the period 1986–2007
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-11)Biomonitoring studies are helpful tools and can increase our knowledge on time trends in human blood concentrations of PFASs: how they relate to emission trends and the potential prenatal exposure for future generations. In this study, serum was sampled in cross-sections of men and women who were 30 years old in each of the years 1986, 1994, 2001, and 2007 in Northern Norway and analyzed for 23 ... -
Måleegenskaper ved den norske versjonen av Kartlegging av traumatiske erfaringer (KATES-Barn)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-19)Beskrivelse. Kartlegging av traumeerfaringer og symptomer (KATES Barn) er et screeninginstrument for barn i alderen 7–17 år som gir foreløpig informasjon om mulig posttraumatisk stress. KATES Barn kommer i to deler; del 1 fanger opp traumatiske hendelser, og del 2 måler symptomer på posttraumatisk stress. Del 2 er delt opp i fire symptomkategorier tilpasset de diagnostiske endringene av traumediagnosen ... -
HPyV6 and HPyV7 in urine from immunocompromised patients
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-22)Background - Human polyomavirus 6 (HPyV6) and HPyV7 are two of the novel polyomaviruses that were originally detected in non-diseased skin. Serological studies have shown that these viruses are ubiquitous in the healthy adult population with seroprevalence up to 88% for HPyV6 and 72% for HPyV7. Both viruses are associated with pruritic skin eruption in immunocompromised patients, but a role with ... -
DNA Damage Response
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-19) -
The Educational Gradient in Intake of Energy and Macronutrients in the General Adult and Elderly Population: The Tromsø Study 2015–2016
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-28)Worldwide, there are socioeconomic inequalities in health and diet. We studied the relationship between education and nutrient intake in 11,302 women and men aged 40–96 years who participated in the seventh survey of the population-based Tromsø Study (2015–2016), Norway (attendance 65%). Diet was assessed using a validated food-frequency questionnaire. We examined the association between education ... -
Prevalence, diversity and transferability of the Tn916-Tn1545 family ICE in oral streptococci
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-15)<i>Background</i>: The Tn<i>916</i>-Tn<i>1545</i> family of Integrative Conjugative Elements (ICE) are mobile genetic elements (MGEs) that play a role in the spread of antibiotic resistance genes. The Tn<i>916</i> harbors the tetracycline resistance gene <i>tet</i>(M) and it has been reported in various bacterial species. The increase in the levels of tetracycline resistance among oral streptococci ... -
How physicians manage medical uncertainty: A qualitative study and conceptual taxonomy
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-01)Background - Medical uncertainty is a pervasive and important problem, but the strategies physicians use to manage it have not been systematically described.<p> <p>Objectives - To explore the uncertainty management strategies employed by physicians practicing in acute-care hospital settings and to organize these strategies within a conceptual taxonomy that can guide further efforts to understand ... -
Demografisk utvikling og potensialet for uformell omsorg i Norge
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-11)Bakgrunn: Myndighetene har forventninger om at bidrag fra pårørende og frivillige i omsorg for hjemmeboende eldre skal opprettholdes på dagens nivå eller økes i fremtiden. I artikkelen undersøker vi potensialet for uformell omsorg med utgangspunkt i den demografiske utviklingen frem mot 2040. Metode: Med utgangspunkt i folketall fra 2018 og Statistisk sentralbyrås befolkningsframskrivinger 2018–2040 ... -
Factors associated with the establishment of new occupational therapist positions in Norwegian municipalities after the Coordination reform
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-16)Community-based occupational therapy is an increasingly important domain of work for occupational therapists. In Norway, this has been emphasized by the Coordination reform (2012), which assigned municipalities increased responsibility to protect and promote the health of their inhabitants. However, even if approximately 400 positions have been established between 2012 and 2017, little is known ...
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