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Overexpression of miR-20a-5p in Tumor Epithelium Is an Independent Negative Prognostic Indicator in Prostate Cancer — A Multi-Institutional Study
(Master thesis; Mastergradsoppgave; Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-26)<p><i>Background:</i> MicroRNAs (miRs) have critical regulatory roles in cell functions, and are involved in prostate cancer tumorigenesis. miR-20a-5p is a member of the oncogenic miR-17-92 cluster. Overexpressed miR-20a-5p has been shown to increase both cell proliferation and cell migration in cancers. The aim of our cohort study was to evaluate the prognostic role of miR-20a-5p in prostate cancer. ... -
Mobile app as a tool to collect health data: a survey on vaccination against COVID-19
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022)Objective. To evaluate the feasibility of using a mobile app to collect health-related data and the impact of this data collection method on the results obtained, using the COVID-19 vaccination attitude assessment as an example. Material and methods. A survey was conducted on attitudes towards COVID-19 vaccination using the «Know Your Heart» mobile app. A total of 1,770 Arkhangelsk region residents ... -
Regression-based norms for the FAS phonemic fluency test for ages 40–84 based on a Norwegian sample
(Mastergradsoppgave; Master thesis, 2023-01-06)The FAS phonemic fluency test is a commonly used neuropsychological test of executive function and processing speed. Although Norwegian discrete norms have been developed for the FAS test, American regression-based norms are frequently used by clinicians in Norway. However, language and cultural differences impact performance on the FAS test, and using foreign norms may not be appropriate. Moreover, ... -
Factors associated with treatment satisfaction in patients with hidradenitis suppurativa: results from the Global VOICE project
(Journal article; Tidsskriftartikkel, 2022-12-01)<p><i>Background</i> Nearly half of patients with hidradenitis suppurativa (HS) report dissatisfaction with their treatment. However, factors related to treatment satisfaction have not been explored. <p><i>Objectives</i> To measure associations between treatment satisfaction and clinical and treatment‐related characteristics among patients with HS. <p><i>Methods</i> Treatment satisfaction was ... -
Association of lipid-lowering drugs and antidiabetic drugs with age-related macular degeneration: A meta-analysis in Europeans
(Journal article; Tidsskriftartikkel, 2022-11-07)<p><i>Background/aims</i> To investigate the association of commonly used systemic medications with prevalent age-related macular degeneration (AMD) in the general population. <p><i>Methods</i> We included 38 694 adults from 14 population-based and hospital-based studies from the European Eye Epidemiology consortium. We examined associations between the use of systemic medications and any prevalent ... -
Note to first-year university students: Just do it! In the end, the fact that you study may be more important than how you study.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-20)Education is important to society, yet many students do not complete the educations they start. In the present study of 426 students at a Norwegian university, we examined the predictive value of study-related variables with regard to student status one and five years after initial enrollment (stayers versus dropouts). The logistic regression analyses indicated that older students and students who ... -
Neuroendocrinology of sexual behavior
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-08)One of the consequences of sexual behavior is reproduction. Thus, this behavior is essential for the survival of the species. However, the individual engaged in sexual behavior is rarely aware of its reproductive consequences. In fact, the human is probably the only species in which sexual acts may be performed with the explicit purpose of reproduction. Most human sexual activities as well as sex ... -
Fødselsrift – hva så? Kvinners vurdering av informasjon om fødselsrift mottatt på barselavdelingen, oppfølgingen de mottar, og betydningen av informasjonen for bekymringer, utfordringer og mestring av fødselsriften de første seks måneder etter fødsel
(Master thesis; Mastergradsoppgave, 2022-03-16)Bakgrunn: Kvinner som rammes av en fødselsrift kan ha et udekt informasjonsbehov. Mangel på informasjon kan føre til utfordringer relatert til fysisk og psykisk helse, uavhengig av hvilken grad av rift som er ervervet. Hensikt: Hensikten med studien var å kartlegge kvinners vurdering av informasjonen mottatt om sin fødselsrift på barselavdelingen, erfaringen med oppfølgingen fra helsevesenet ... -
Sharing food with infants in Hadza communities in Tanzania
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-28)By analyzing mealtime interactions of Tanzanian Hadza infants with their interactional partners, we explored how two foundational schemas, namely giving/sharing and autonomy are realized and fostered in infants. We focused on three aspects of the mealtime interactions, namely how the infants’ share was protected, whether independent eating was fostered by the infants’ interactional partners, and ... -
Stable or unstable associations between learning environment factors, study approaches and exam grades: cross-sectional analyses across two consecutive program years
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-31)Studies into the relationships between learning environment perceptions, approaches to studying, and academic outcomes have largely followed cross-sectional designs. As a result, knowledge is sparse with regards to whether, or to what degree, the established associations are consistent across years of study. This study aimed to (i) examine associations between occupational therapy students’ academic ... -
The mental health consequences on children of the war in Ukraine: A commentary
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-18)The news from Ukraine is currently full of heart-wrenching stories accompanied by graphic images of civilian casualties and massacres that are telecast world-wide on a daily basis. It is hard to fathom the magnitude of the devastation and disruption to regular lives and everyday routines that war brings with it, the witnessing of countless deaths, the associated trauma of living in perpetual fear, ... -
Plasma levels of platelet-derived microvesicles are associated with risk of future venous thromboembolism
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-18)Background - Microvesicles (MVs) are small double‐membrane encapsulated particles shed from cells. Case‐control studies have reported elevated plasma levels of platelet‐derived MVs (PDMVs) in patients with venous thromboembolism (VTE). However, it is not known whether high PDMV levels is a risk factor or a consequence of the acute VTE event.<p> <p>Objectives - To investigate the association between ... -
Joint Effect of Multiple Prothrombotic Genotypes and Mean Platelet Volume on the Risk of Incident Venous Thromboembolism
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-31)Background - A high mean platelet volume (MPV), a marker of increased platelet reactivity, is a risk factor for venous thromboembolism (VTE). Whether established prothrombotic single nucleotide polymorphisms (SNPs) further increase the VTE risk in subjects with high MPV because of biological interaction remains unknown.<p> <p>Aim - To investigate the joint effect of high MPV and prothrombotic ... -
Association between Carbonic Anhydrase VI (CA VI) gene copy number and dental caries experience
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022)The current study examined the association between the carbonic anhydrase VI (CA VI) copy number variations (CNVs) and dental caries experience in adults. In total, 202 of 35-72 years old subjects participating in the Lithuanian National Oral Health Survey (LNOHS) agreed to provide saliva samples, thus their data were included in the current study. Information about sociodemographic, environmental, ... -
Dental composites - The effects of matrix composition, suboptimal light curing and water exposure
(Doctoral thesis; Doktorgradsavhandling, 2023-03-30)In Scandinavian countries, resin-based composite materials have been used in restorative dentistry for over 30 years, replacing dental amalgams. Composite materials based on dimethacrylates provide better aesthetics and treatment options. However, according to in-vitro findings, dental composites can be affected by water, potentially reducing the longevity of dental restorations. The proper ... -
Adolescents’ Assessment of Two Mental Health–Promoting Mobile Apps: Results of Two User Surveys
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-06)To examine the impact of migration and acculturation of Turkish men who have sex with men (MSM) to Germany, using data from the European MSM Internet Survey (EMIS-2010), on measures of acculturation including circumcision status, internalized homonegativity (IH), HIV/STI knowledge, sexual orientation, outness, HIV-testing, and sexual behaviors. We compared four groups of MSM: MSM born and residing ... -
Impact of Migration and Acculturation on Turkish Men Who Have Sex with Men in Germany: Results from the 2010 European MSM Internet Survey
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-17)To examine the impact of migration and acculturation of Turkish men who have sex with men (MSM) to Germany, using data from the European MSM Internet Survey (EMIS-2010), on measures of acculturation including circumcision status, internalized homonegativity (IH), HIV/STI knowledge, sexual orientation, outness, HIV-testing, and sexual behaviors. We compared four groups of MSM: MSM born and residing ... -
Should I Stay or Should I Go? The Role of Daily Presenteeism as an Adaptive Response to Perform at Work Despite Somatic Complaints for Employee Effectiveness
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022)Our study seeks to contribute to scholarly understanding of the antecedents and consequences of the crucial, but so far overlooked within-person daily fluctuations in presenteeism. Drawing on theoretical frameworks of presenteeism, which conceptualize presenteeism as an adaptive behavior to deliver work performance despite limitations due to ill-health, we develop a within-person model of daily ... -
Prevalence of unruptured intracranial aneurysms: impact of different definitions-the Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-10)Background - Management of incidental unruptured intracranial aneurysms (UIAs) remains challenging and depends on their risk of rupture, estimated from the assumed prevalence of aneurysms and the incidence of aneurysmal subarachnoid haemorrhage. Reported prevalence varies, and consistent criteria for definition of UIAs are lacking. We aimed to study the prevalence of UIAs in a general population ... -
Blood cell DNA methylation biomarkers in preclinical malignant pleural mesothelioma: The EPIC prospective cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-28)Malignant pleural mesothelioma (MPM) is a rare and aggressive cancer mainly caused by asbestos exposure. Specific and sensitive noninvasive biomarkers may facilitate and enhance screening programs for the early detection of cancer. We investigated DNA methylation (DNAm) profiles in MPM prediagnostic blood samples in a case-control study nested in the European Prospective Investigation into Cancer ...
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