Recent additions

  • Prehospital tourniquets in civilians: A systematic review 

    Eilertsen, Kenneth A.; Winberg, Morten; Jeppesen, Elisabeth; Hval, Gyri; Wisborg, Torben (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-03)
    Objectives: Terrorist attacks and civilian mass-casualty events are frequent, and some countries have implemented tourniquet use for uncontrollable extremity bleeding in civilian settings. The aim of this study was to summarize current knowledge on the use of prehospital tourniquets to assess whether their use increases the survival rate in civilian patients with life-threatening hemorrhages from ...
  • Volume blood flow-based indices of fetal brain sparing in the second half of pregnancy: A longitudinal study 

    Stefopoulou, Maria; Johnson, Jonas; Wilsgaard, Tom; Lindgren, Peter; Herling, Lotta; Kiserud, Torvid; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-07)
    <i>Introduction</i> - Cerebroplacental ratio (CPR) and umbilicocerebral ratio (UCR) are clinically used as a measure of fetal brain sparing. These are calculated as the ratios between the pulsatility indices (PIs) of middle cerebral (MCA) and umbilical (UA) arteries, and are an indirect representation of the balance between cerebral and placental perfusion. Volume blood flow (Q)‐based ratios, ie ...
  • Gastrointestinal stromal tumor (GIST) operert ved UNN Tromsø 1999-2019: forekomst, karakteristika og overlevelse 

    Olsen, Ida Zhang (Master thesis; Mastergradsoppgave, 2020-08-28)
    Bakgrunn: Gastrointestinal stromal tumor (GIST) er den vanligste mesenkymale svulsten i fordøyekseskanalen, og ble definert som en egen svulsttype rundt 1999. Tidligere trodde man at denne svulsttypen utgikk fra muskulatur eller nervevev, men man vet nå at de utgår fra såkalte pacemakerceller kalt Interstitiale Cajalske Celler (ICC). De forekommer oftest i ventrikkel og tynntarm, men svulster kan ...
  • Koppevirus egnethet som biologisk våpen 

    Johnsen, Yrian Castillejo (Master thesis; Mastergradsoppgave, 2020-08-26)
    Variola ble offisielt erklært utryddet i 1980. Viruset finnes nå kun lagret offisielt i USA og Russland. Til tross for dette er det stor frykt for at viruset kan komme på avveie og brukes som agens i biologiske våpen. Denne oppgaven utforsker koppevirusets egnethet som biologisk våpen, samt hvor reell en slik trussel faktisk er i dagens moderne samfunn.
  • Self-reported food hypersensitivity in relation to biomarkers: The Fit Futures Study 

    Dragland, Vilde (Master thesis; Mastergradsoppgave, 2020-08-19)
    Food hypersensitivity is recognized as a rather common condition, that can occur at any age. There is limited high-quality data on the burden of this condition, especially after child age. The aim of this thesis has been to explore whether levels of biomarkers in blood differ between adolescents with self-reported hypersensitivity against certain food and the control group in a general youth population. ...
  • Bruk av tvangsmidler ved Psykisk helse- og rusklinikken, UNN HF 

    Nordbotten, Åshild (Master thesis; Mastergradsoppgave, 2020-08-14)
    Pasienter innlagt i psykisk helsevern kan, på gitte juridiske vilkår, unntas det grunnleggende prinsippet om at all behandling og tiltak skal være frivillig. Dette setter strenge krav til dem som utfører helsetjenestene, og da også til kontroll av bruk av tvang. I 2016 kom det en kritisk rapport fra Sivilombudsmannen om bruk av tvang ved Psykisk Helse- og rusklinikken, UNN HF. Det ble i etterkant ...
  • ECMO eller Impella ved akutt hjertesvikt - en litteraturstudie 

    Jensen, Ane Karoline Slettbakk (Master thesis; Mastergradsoppgave, 2020-11-10)
    Innledning Formålet med denne oppgaven er å systematiseres dokumentasjonsgrunnlaget for bruk av ECMO og/eller Impella ved de tre angitte presentasjonene av akutt hjertesvikt (kardiogent sjokk, postkardiotomisjokk og hjertestans). I denne oppgaven vil foreliggende litteratur vurderes for å finne om man bedre kan selektere pasienter til det pumpesystemet som vil gi størst kliniske effekt av behandlingen. ...
  • Korttidsresultater og reseksjonsmarginer for leverreseksjoner ved UNN etter implementering av laparoskopisk teknikk. 

    Paulsen, Regine Liavik (Master thesis; Mastergradsoppgave, 2020-07-05)
    Bakgrunn: Leverreseksjoner utføres på bred indikasjon, og er en etablert behandlingsform for både maligne og benigne tilstander. Prosedyren har tradisjonelt sett vært utført med åpen teknikk, men i de senere år har også laparoskopi fått sin plass i behandlingen. Formålet med denne oppgaven er å beskrive utvikling i bruk av lapasoskopi, indikasjoner, komplikasjoner og reseksjonsmarginer for ...
  • Are the Relationships of Lean Mass and Fat Mass With Bone Microarchitecture Causal or Due to Familial Confounders? A Novel Study of Adult Female Twin Pairs 

    Bui, Minh; Zebaze, Roger; Li, Shuai; Hopper, John L.; Bjørnerem, Åshild (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-01)
    It is not known whether the relationships of lean mass (LM) and fat mass (FM) with bone microarchitecture and geometry are causal and/or are because of confounders, including familial confounders arising from genetic and environment effects shared by relatives. We tested the hypotheses that: (i) LM is associated with cortical bone traits, (ii) FM is associated with trabecular bone traits, and (iii) ...
  • Evaluating a centralised cancer support centre in the remote region of Northern Norway 

    Ervik, Bente; Andersen, Sigve; Skirbekk, Helge; Dønnem, Tom (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-20)
    Introduction: Being diagnosed with cancer and undergoing treatment is a life-changing experience, and many cancer patients find the physical, emotional and social effects of the disease to be stressful. This study explores the experiences of cancer patients and their relatives from all parts of Northern Norway visiting the centralised cancer support centre. <p> <p>Methods: In a comprehensive ...
  • Exploring the roles of TRIM27 and TRIM32 in autophagy 

    Garcia Garcia, Juncal (Doctoral thesis; Doktorgradsavhandling, 2021-05-21)
    <p>Tripartite motif family proteins (TRIMs) are a wide family of E3 ligases involved in the control of several cellular processes such as intracellular signaling, innate immunity, transcription, cell cycle regulation and carcinogenesis. In recent years, some members of this family have been found to have a role in autophagy. <p>The central theme of this thesis is the role of two TRIM proteins in ...
  • Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants 

    Rodriguez-Martinez, Andrea; Zhou, Bin; Sophiea, Marisa K.; Bentham, James; Paciorek, Christopher J.; Turilli, Maria L.C.; Andersen, Lars Bo; Anderssen, Sigmund Alfred; Ariansen, Inger Kristine Holtermann; Bjertness, Espen; Bjertness, Marius Bergsmark; Ekelund, Ulf; Graff-Iversen, Sidsel; Grøholt, Else Karin; Haugsgjerd, Teresa Risan; Bergh, Ingunn Holden; Janszky, Imre; Kolle, Elin; Krokstad, Steinar; Madar, Ahmed Ali; Sen, Abhijit; Skodje, Gry Irene; Sørgjerd, Elin Pettersen; Nilsen, Bente; Steene-Johannessen, Jostein; Tarp, Jakob; Tell, Grete S.; Torheim, Liv Elin; Wilsgaard, Tom; Carrillo-Larco, Rodrigo M.; Bennett, James E.; Di Cesare, Mariachiara; Taddei, Cristina; Bixby, Honor; Stevens, Gretchen A.; Riley, Leanne M.; Cowan, Melanie J.; Savin, Stefan; Danaei, Goodarz; Chirita-Emandi, Adela; Kengne, Andre P; Khang, Young-Ho; Laxmaiah, Avula; Malekzadeh, Reza; Miranda, Jaime; Moon, Jin Soo; Popovic, Stevo; Sørensen, Thorkild I.A.; Soric, Maroje; Starc, Gregor (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-07)
    Background - Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents.<p> <p>Methods - For this pooled analysis, we used a database of cardiometabolic ...
  • Choice of immunoassay to evaluate porcine cytokine levels 

    Ueland, Nora Lamark; Ludvigsen, Judith K.; Hellerud, Bernt C; Mollnes, Tom Eirik; Skjeflo, Espen Waage (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-06)
    <i>Background</i> - In order to adequately monitor cytokines in experimental models, currently available methods and commercially available kits should be compared.<br><br> <i>Aim</i> - To compare the plasma and tissue concentrations of IL-1β, IL-6, IL-8, IL-10, and TNF as a measure of systemic inflammation in septic pigs.<br><br> <i>Methods</i> - Cytokines were quantified from blood and tissue ...
  • The role of psychosocial factors and treatment need in dental service use and oral health among adults in Norway 

    Jönsson, Birgitta; Holde, Gro Eirin; Baker, Sarah R. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-11)
    <i>Objectives</i> - This study aimed to explore whether population characteristics were associated with the use of dental services, individual's personal oral health practices, dental caries and oral health‐related impacts using the revised Andersen's behavioural model as the theoretical framework.<br><br> <i>Methods</i> - This cross‐sectional study included participants from a Norwegian general ...
  • Hemodynamic effects of a soluble guanylate cyclase stimulator, Riociguat, and an activator, Cinaciguat, during NO-modulation in healthy pigs 

    Næsheim, Torvind; How, Ole-Jakob; Myrmel, Truls (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-14)
    Cardiovascular diseases are often characterized by dysfunctional endothelium. To compensate for the related lack of nitric oxide (NO), a class of soluble guanylate cyclase (sGC) stimulators and activators have been developed with the purpose of acting downstream of NO in the NO-sGC-cGMP cascade. These drugs have been discovered using photoaffinity labeling of sGC and high-throughput screening of a ...
  • Labour outcomes with defibulation at delivery in immigrant Somali and Sudanese women with type III female genital mutilation/cutting 

    Rouzi, Abdulrahim A.; Berg, Rigmor; Al-Wassia, Heidi; Alamoudi, Rana; Hariri, Wajeh; Sindi, Ghazi; Almansouri, Nisma; Sahly, Nora (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-24)
    INTRODUCTION There is a scarcity of studies on labour outcomes with defibulation. This study assessed the outcomes of labour with defibulation at delivery in women with type III female genital mutilation/cutting (FGM/C) compared to labour without defibulation. METHODS We identified and reviewed the records of all Somali and Sudanese women who delivered at King Abdulaziz University Hospital, ...
  • Yersinia enterocolitica: A Follow-up of the Outbreak in the Norwegian Armed Forces in 2014 

    Borud, Einar Kristian; Håberg, Siri Eldevik; Norheim, Arne Johan; Strand, Leif Åge; Fadum, Elin Anita (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-28)
    Introduction - In the spring of 2014, there was an outbreak of Yersinia enterocolitica (YE) gastroenteritis in four Norwegian military camps—the largest outbreak ever reported in Norway. YE is usually transmitted via food, and the gastrointestinal disease caused by the bacterium is considered a public health problem in several countries. Common symptoms of YE gastroenteritis are abdominal pain, ...
  • Recurrent disease after treatment for cervical intraepithelial neoplasia-The importance of a flawless definition of residual disease and length of follow-up 

    Bjørnerem, Mathilde Seeger; Sørbye, Sveinung; Skjeldestad, Finn Egil (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-09)
    Objective - To evaluate adherence to national guidelines for follow-up, and assess residual and recurrent disease after treatment for cervical intraepithelial neoplasia grade 2 or worse (CIN2+).<p> <p>Study design - In a case-series design women aged 25–69 years treated for primary CIN2+ in 2006–2011 (n = 752) were followed through August 9, 2019 for residual or recurrent disease, i.e., CIN2+ ...
  • Effects of a parent-administered exercise program in the neonatal intensive care unit: Dose does matter-a randomized controlled trial 

    Øberg, Gunn Kristin; Girolami, Gay L; Campell, Suzann K.; Ustad, Tordis; Heuch, Ivar; Jacobsen, Bjarne K.; Kaaresen, Per Ivar; Aulie, Vibeke Smith; Jørgensen, Lone (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-06)
    Background - Despite the risk of delayed motor development in infants born preterm, knowledge about interventions in the neonatal intensive care unitt (NICU) and the effects of dosing is sparse. <p> <p>Objective - The objectives of this study were to examine the effectiveness of a parent-administered exercise program in the NICU on motor outcome at 3 months corrected age (CA) and the effect of ...
  • STudy of Antithrombotic Treatment after IntraCerebral Haemorrhage: Protocol for a randomised controlled trial 

    Larsen, Kristin Tveitan; Forfang, Elisabeth; Pennlert, Johanna; Glader, Eva-Lotta; Kruuse, Christina; Wester, Per; Ihle-Hansen, Hege; Carlsson, Maria; Berge, Eivind; Al-Shahi Salman, Rustam; Wyller, Torgeir Bruun; Rønning, Ole M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-03)
    Background and aims - Many patients with prior intracerebral haemorrhage have indications for antithrombotic treatment with antiplatelet or anticoagulant drugs for prevention of ischaemic events, but it is uncertain whether such treatment is beneficial after intracerebral haemorrhage. STudy of Antithrombotic Treatment after IntraCerebral Haemorrhage will assess (i) the effects of long-term antithrombotic ...

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