Recent additions

  • The Harstad injury prevention study : hospital-based injury recording and community-based intervention 

    Ytterstad, Børge (Doctoral thesis; Doktorgradsavhandling, 1995)
    Accidental injury is the leading cause of death in Norway under the age of 50. A 19 % reduction of age standardized accident mortality was observed from 1956 to 1983. In spite of this, next to Finland, Norway has the highest accident mortality rate among the Nordic countries (1) . To reduce accidental injury it is important to gain knowledge about all injuries, not only the fatal ones. The ...
  • Fibroblast growth factor 2 conjugated with monomethyl auristatin E inhibits tumor growth in a mouse model 

    Krzyscik, Mateusz Adam; Zakrzewska, Malgorzata; Sørensen, Vigdis; Øy, Geir Frode; Bruheim, Skjalg; Haugsten, Ellen Margrethe; Mælandsmo, Gunhild Mari; Wiedlocha, Antoni; Otlewski, Jacek (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-20)
    Worldwide, cancer is the second leading cause of death. Regardless of the continuous progress in medicine, we still do not have a fully effective anti-cancer therapy. Therefore, the search for new targeted anti-cancer drugs is still an unmet need. Here, we present novel protein–drug conjugates that inhibit tumor growth in a mouse model of human breast cancer. We developed conjugates based on fibroblast ...
  • Patterns and predictors of drug use : a pharmacoepidemiologic study, linking the analgesic drug prescription to a population health survey in Tromsø, Norway 

    Eggen, Anne Elise (Doctoral thesis; Doktorgradsavhandling, 1994)
    The purpose of the study may be summarized as follows: - What is the frequency of drug use in the population, frequency of analgesic drug use in general and particularly the use of controlled analgesics? - How will morbidity, demographic pattern and lifestyle characteristics influence this drug use, and which factors explain the observed differences in drug use?
  • The healthy faith : pregnancy outcome, risk of disease, cancer morbidity and mortality in Norwegian Seventh-Day Adventists 

    Fønnebø, Vinjar (Doctoral thesis; Doktorgradsavhandling, 1992)
    The aim of the present study was to examine the association between being a Seventh-Day Adventist and risk factors for disease, pregnancy outcome, cancer incidence, site-specific mortality and total mortality in an unselected Seventh-Day Adventist population.
  • Nifedipine disturbs fetal cardiac function during hypoxemia in a chronic sheep model at near term gestation 

    Alanne, Leena; Bhide, Amarnath Govind; Lantto, Juulia; Huhta, Heikki; Kokki, Merja; Haapsamo, Mervi; Acharya, Ganesh; Rasanen, Juha (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11)
    Background: Nifedipine is a widely used drug in pregnancies complicated by maternal hypertensive disorders that can be associated with placental insufficiency and fetal hypoxemia. The evidence regarding fetal myocardial responses to nifedipine in hypoxemia is limited.<p> <p>Objective: We hypothesized that nifedipine would not impair fetal sheep cardiac function under hypoxemic environment. In ...
  • Quality of life among women with symptomatic, screen-detected, and interval breast cancer, and for women without breast cancer: a retrospective cross-sectional study from Norway 

    Moshina, Nataliia; Falk, Ragnhild Sørum; Botteri, Edoardo; Larsen, Marthe; Akslen, Lars Andreas; Cairns, John Alexander; Hofvind, Solveig (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-26)
    Purpose - Breast cancers detected at screening need less aggressive treatment compared to breast cancers detected due to symptoms. The evidence on the quality of life associated with screen-detected versus symptomatic breast cancer is sparse. This study aimed to compare quality of life among Norwegian women with symptomatic, screen-detected and interval breast cancer, and women without breast cancer ...
  • Our climatic environment and pain. Exposure to cold environment at work and the weather in daily life 

    Farbu, Erlend Hoftun (Doctoral thesis; Doktorgradsavhandling, 2021-12-20)
    Chronic pain is a major health challenge, and musculoskeletal pain is among the main contributors to years lived with disability worldwide. Earlier research found an association between cold exposure at work and musculoskeletal pain. However, the literature is scarce, especially regarding chronic pain. It is a common belief that weather affects pain experience, but the literature on this topic is ...
  • Inhibition of ABCC5-mediated cGMP transport by progesterone, testosterone and their analogues 

    Odland, Sondre Ulstein; Ravna, Aina Westrheim; Smaglyukova, Natalia; Dietrichs, Erik Sveberg; Sager, Georg (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-13)
    The biodynamics and biokinetics of sex hormones are complex. In addition to the classical steroid receptors (nuclear receptors), these hormones act through several non-genomic mechanisms. Modulation of ABC-transporters by progesterone represents a non-genomic mechanism. In the present study, we employed inside out vesicles from human erythrocytes to characterize high affinity cGMP transport by ABCC5 ...
  • Blodtrykksovervåking og blodtrykksmåling 

    Kvamme, Jan-Ivar; Nesje, Bernt; Forsdahl, Anders (Others; Andre, 1983)
    Som ledd i en bedre blodtrykksbehandling, har vi utarbeidet vedlagte skjema for blodtrykksovervåkning. Hensikten med skjemaet er at en skal få en bedre oversikt over anamnese, utredninger og kontroller. Et vesentlig punkt i blodtrykksovervåkningen er også en standardisering av målemetodene. Vi har derfor gitt anbefalinger om standardisering og omtalt en del feilkilder i forbindelse med målingene.
  • Effects of antibiotics on the developing enamel in neonatal mice 

    Schmalfuss, A.J.; Sehic, Amer; Brusevold, Ingvild Johnsen (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-29)
    Purpose Identifying factors causing Molar-Incisor Hypomineralization (MIH) is an ongoing challenge. Preterm infants, routinely treated with antibiotics in cases of suspected sepsis, are more commonly afected by dental developmental defects. This study aimed to investigate the efects of gentamycin and ampicillin on the developing enamel in neonatal CD-1 mice in vivo.<p> <p>Methods Neonatal mice ...
  • Estimated lifetime risk of venous thromboembolism in men and women in a Danish nationwide cohort: impact of competing risk of death 

    Arnesen, Carl Arne Løchen; Veres, Katalin; Horváth-Puhó, Erzsébet; Hansen, John-Bjarne; Sørensen, Henrik Toft; Brækkan, Sigrid K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-08)
    Incidence of venous thromboembolism (VTE) risk varies by age and sex. Some studies have reported overall higher risk in men, especially when VTEs triggered by female reproductive factors are excluded. However, higher mortality rates in men may have led to overestimation of lifetime VTE risk in men compared with women. Therefore, we estimated the lifetime risk of VTE in men and women in a Danish, ...
  • Cardiovascular responses to dynamic and static upper-body exercise in a cold environment in coronary artery disease patients 

    Valtonen, Rasmus; Hintsala, Heidi; Kiviniemi, Antti; Kentta, Tuomas; Crandall, Craig; van Marken Lichtenbelt, Wouter; Perkiomaki, Juha; Hautala, Arto; Jaakkola, Jouni; Ikäheimo, Tiina (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-16)
    Purpose - Upper-body exercise performed in a cold environment may increase cardiovascular strain, which could be detrimental to patients with coronary artery disease (CAD). This study compared cardiovascular responses of CAD patients during graded upper-body dynamic and static exercise in cold and neutral environments.<p> <p>Methods - 20 patients with stable CAD performed 30 min of progressive ...
  • ISUOG Practice Guidelines (updated): use of Doppler velocimetry in obstetrics 

    Bhide, Amarnath; Acharya, Ganesh; Baschat, Ahmet Alexander; Bilardo, Caterina Maddalena; Brezinka, Christoph; Cafici, Daniel; Ebbing, Cathrine; Hernandez-Andrade, Edgar A.; Kalache, Karim; Kingdom, John; Kiserud, Torvid; Surendran, Sailesh Kumar; Lee, Wesley; Lees, Christoph; Leung, Kwok Yin; Malinger, Gustavo; Mari, Giancarlo; Prefumo, Federico; Sepulveda, Waldo; Trudinger, Brian (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-19)
    The International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) is a scientific organization that encourages sound clinical practice, teaching and research related to diagnostic imaging in women's healthcare. The ISUOG Clinical Standards Committee (CSC) has a remit to develop Practice Guidelines and Consensus Statements as educational recommendations that provide healthcare practitioners ...
  • IARC monographs: 40 years of evaluating carcinogenic hazards to humans 

    Pearce, Neil; Blair, Aaron; Vineis, Paolo; Ahrens, Wolfgang; Andersen, Aage; Anto, Josep M.; Armstrong, Bruce K.; Baccarelli, Andrea A.; Beland, Frederick A.; Berrington, Amy; Bertazzi, Pier Alberto; Birmbaum, Linda S.; Brownson, Ross C.; Bucher, John R.; Cantor, Kenneth P.; Cardis, Elisabeth; Cherrie, John W.; Christiani, David C.; Cocco, Pierluigi; Coggon, David; Comba, Pietro; Demers, Paul A.; Dement, John M.; Douwes, Jerouen; Eisen, Ellen A.; Engel, Lawrence S.; Fenske, Richard A.; Fleming, Lora E.; Fletcher, Tony; Fontham, Elizabeth; Forastiere, Francesco; Frentzel-Beyme, Rainer; Fritschi, Lin; Gerin, Michel; Goldberg, Marcel; Grandjean, Philippe; Grimsrud, Tom Kristian; Gustavsson, Per; Haines, Andy; Hartge, Patricia; Hansen, Johnni; Hauptmann, Michael; Heederick, Dick; Hemminki, Kari; Hemon, Denis; Hertz-Picciotto, Irva; Hoppin, Jane A.; Huff, James; Jarvholm, Bengt; Kang, Daehee; Karagas, Margaret R.; Kjærheim, Kristina; Kjuus, Helge; Kogevinas, Manolis; Kriebel, David; Kristensen, Petter; Kromhout, Hans; Laden, Francine; Lebailly, Pierre; LeMasters, Grace; Lubin, Jay H.; Lynch, Charles F.; Lynge, Elsebeth; ‘t Mannetje, Andrea; McMichael, Anthony J.; McLaughlin, John R.; Marrett, Loraine; Martuzzi, Marco; Merchant, James A.; Merler, Enzo; Merletti, Franco; Miller, Anthony; Mirer, Franklin E.; Monson, Richard; Nordby, Karl-Christian; Olshan, Andrew F.; Parent, Marie-Elise; Perera, Frederica P.; Perry, Melissa J.; Pesatori, Angela Cecilia; Pirastu, Roberta; Porta, Miquel; Pukkala, Eero; Rice, Carol; Richardson, David B.; Ritter, Leonard; Ritz, Beate; Ronckers, Cecile M.; Rushton, Lesley; Rusiecki, Jennifer A.; Rusyn, Ivan; Samet, Jonathan M.; Sandler, Dale P.; de Sanjose, Silvia; Schernhammer, Eva; Costantini, Adele Seniori; Seixas, Noah; Shy, Carl; Siemiatycki, Jack; Silverman, Debra T.; Simonato, Lorenzo; Smith, Allan H.; Smith, Martyn T.; Spinelli, John J.; Spitz, Margaret R.; Stallones, Lorann; Stayner, Leslie T.; Steenland, Kyle; Stenzel, Mark; Stewart, Bernard W.; Stewart, Patricia A.; Symanski, Elaine; Terracini, Benedetto; Tolbert, Paige E.; Vainio, Harri; Vena, John; Vermeulen, Roel; Victora, Cesar G.; Ward, Elizabeth M.; Weinberg, Clarice R.; Weisenburger, Dennis; Wesseling, Catharina; Weiderpass, Elisabete; Zahm, Shelia Hoar (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-24)
    Background: Recently, the International Agency for Research on Cancer (IARC) Programme for the Evaluation of Carcinogenic Risks to Humans has been criticized for several of its evaluations, and also for the approach used to perform these evaluations. Some critics have claimed that failures of IARC Working Groups to recognize study weaknesses and biases of Working Group members have led to inappropriate ...
  • Psychological factors and performance in women’s football: A systematic review 

    Adolfsen, Frode; Martinussen, Monica (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-05)
    The amount of research conducted on female football players, compared to male players, is sparce. Even though research on female football players has increased the past decade, there is still a lack of studies of how psychological factors affect their performance. The objective of the current systematic review was therefore to summarize existing quantitative research into the relationship between ...
  • Perceived study-induced influence on the control group in a randomized controlled trial evaluating a complex intervention to promote psychosocial well-being after stroke: a process evaluation 

    Mangset, Margrete; Kitzmüller, Gabriele; Evju, Anne Svelstad; Angel, Sanne; Aadal, Lena; Martinsen, Randi Elisabeth; Bronken, Berit Arnesveen; Bragstad, Line Kildal; Hjelle, Ellen Gabrielsen; Sveen, Unni; Kirkevold, Marit; Kvigne, Kari J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-27)
    Background A commonly applied control condition in trials evaluating complex interventions in rehabilitation research is “usual care.” The main challenge is to ensure that the control group receives genuine usual care as delivered in everyday clinical practice. The assessment interviews and dialogues with the data collectors may influence the control group participants’ reflections on their condition ...
  • Myelinated Retinal Nerve Fibre: Prevalence and its Association with Ocular and Systemic Parameters in Tromsø. 

    Kalu, Dominic Okoro (Mastergradsoppgave; Master thesis, 2020-11-30)
    Background: Myelinated retinal nerve fibres (MRNFs) are congenital anomalies of the fundus that occur in about 1% of the population. Clinically, they appear as grey or white well-separated patches with feathery borders along the retinal nerve fibre layer. MRNF has been reported to occur in association with some ocular parameters as well as stroke. However, most cases of MRNF occur in isolation and ...
  • Hvordan ivaretas samspillsveiledning til foreldre i norske nyfødtintensivenheter? 

    Landsem, Inger Pauline; Vederhus, Bente Johanne; Hagen, Inger Hilde; Wang, Catharina Elisabeth Arfwedson; Øberg, Gunn Kristin; Handegård, Bjørn Helge (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-21)
    Bakgrunn: Nasjonale retningslinjer anbefaler at foreldre til prematurt fødte barn tilbys kunnskapsbasert samspillsveiledning mens barnet er innlagt på sykehus. Forskning viser at foreldreveiledningsprogrammet «Mother-Infant Transaction Program» (MITP-m) kan fremme vedvarende god utvikling og tilpasning i familier med prematurt fødte barn.<p> <p>Hensikt: Denne studien undersøker i hvilken grad ...
  • Physical activity and cutaneous melanoma risk: A Norwegian population-based cohort study 

    Perrier, Flavie; Ghiasvand, Reza; Lergenmuller, Simon; Robsahm, Trude Eid; Green, Adele C.; Borch, Kristin Benjaminsen; Sandanger, Torkjel M; Weiderpass, Elisabete; Rueegg, Corina Silvia; Veierød, Marit Bragelien (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-20)
    Physical activity (PA) is an important factor in cancer prevention, but positive association between PA and risk of cutaneous melanoma found in recent studies may complicate this strategy. Ultraviolet radiation (UVR) exposure during outdoor PA is a plausible explanation for a positive association. We investigated the associations between PA, UVR and melanoma risk in the Norwegian Women and Cancer ...
  • "Eksistensiell omsorg" i bachelorutdanningen i sykepleie - En dokumentanalyse 

    Tornøe, Kirsten; Hillestad, Adelheid Hummelvoll; Breistig, Sigrund; Rosenvinge, Jan H; Pettersen, Gunn; Sørlie, Venke; Hegertun, Rigmor; Eriksen, Liss Trine; Bakland, Maria; Prause, Daniel (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-22)
    Bakgrunn: Sykepleiere møter pasienter der kunnskaper og ferdigheter innen eksistensiell omsorg kan utgjøre en stor forskjell i hvordan pasientene håndterer eksistensielle utfordringer. Både helse- og utdanningsmyndigheter har klare forventninger om at sykepleiere har den nødvendige kompetansen til å ivareta pasientenes eksistensielle behov. En viktig forutsetning er da at undervisningstilbudet ved ...

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