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norskDet helsevitenskapelige fakultet
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Helseattest for kvinnelige langrennsløpere – trenernes erfaringer
(Master thesis; Mastergradsoppgave, 2022-05-13)I 2014 resulterte et samarbeid mellom Sunn Idrett og Olympiatoppen til innføring av en ordning med helseattest. Ordningens mål er å sette helsen til toppidrettsutøvere i norsk friidrett, orientering, langrenn og skiskyting foran prestasjon. Dersom helseattesten avdekker uheldige forhold vedrørende en utøvers helse, kan utøveren få «startnekt» i internasjonale konkurranser. Formålet med denne oppgaven ... -
Sikkerhet og beslutningstaking i profesjonsrettet friluftsliv
(Master thesis; Mastergradsoppgave, 2023-05-13)Denne masteroppgaven i idrettsvitenskap ved Universitet i Tromsø tar utgangspunkt i fagfeltet friluftsliv og temaet sikkerhet og beslutninger i profesjonsrettet friluftsliv. Studiens problemstilling undersøker betydningen av erfaring og overskudd samt strategier for ivaretakelse av overskudd for turledere på Svalbard. Problemstillingen undersøkes gjennom kvalitative forskningsintervju av 5 erfarne ... -
Dual delivery of chlorogenic acid and mimic of antimicrobial peptide – towards wound treatment
(Master thesis; Mastergradsoppgave, 2022-05-12)Chronic wounds are a major burden, causing both morbidity and mortality in patients, as well as a massive economical strain on health care systems worldwide. These wounds have a high degree of complexity and are often difficult to treat due to the many factors limiting healing, such as inflammation, biofilm formation and bacterial infections. With these typically persistent infections and a rising ... -
Chitosan-modified liposomes for delivery of membrane-active antimicrobials – exploring the role of the polymer
(Master thesis; Mastergradsoppgave, 2022-05-12)Antimicrobial resistance in skin injury infections is becoming a rising problem as more conventional antimicrobials become ineffective in resistant infections. Therefore, developing novel effective antimicrobials while promoting wound healing is urgently needed. Membrane-active antimicrobials, such as antimicrobial peptides (AMPs), display promising antimicrobial activity, and could potentially solve ... -
Hvilken innvirkning hadde restriksjonene forbindelse med Covid-19 pandemien på eldres mentale helse og sosiale relasjoner? – en litteraturstudie med systematisk tilnærming
(Master thesis; Mastergradsoppgave, 2022-05-04)<p>Bakgrunn:. Mars 2020 ble verden rammet av en epidemi, Covid-19 pandemien førte til at en rekke land stengte ned og eldre ble bedt om å holde seg innendørs og unngå kontakt med andre, for å beskytte seg mot alvorlig sykdom og død. <p>Hensikt: Hensikten med denne oppgaven var å granske og sammenstille tidligere forskning som har sett på hvordan isolasjon og ensomhet under Covid-19 pandemien har ... -
Characterization of competition between commensal A2 and clinical A1 strains of Enterococcus faecium
(Mastergradsoppgave; Master thesis, 2023-05-14)Enterococcus faecium (E. faecium) emerged from a gut commensal to one of the leading nosocomial multidrug-resistant pathogens. The species of E. faecium, has a deep phylogenetic split into commensal and clinical strains. The dominance of clinical strains during nosocomial infections is only insufficiently understood. Previous studies revealed competitive characteristics between the commensal ... -
Exploring the adenosine system by cancer-associated fibroblasts in the context of radiotherapy
(Mastergradsoppgave; Master thesis, 2023-05-14)Background of the study: Cancer-associated fibroblasts (CAFs) are a heterogeneous population of cells that are mainly found in solid malignancies and play vital roles in tumor progression and metastasis, including important immunoregulatory functions. In this study, our objective was to explore the immunosuppressive adenosine system within the CAFs isolated from non-small cell lung carcinomas (NSCLC) ... -
Using High-Resolution Mass Spectrometry to identify lipids in marine bacterial biomass
(Mastergradsoppgave; Master thesis, 2023-05-14)Background: BMFishfeed is a cooperative project since 2021 between UiT the Arctic University of Norway, NORCE Stavanger and the University of South-Eastern Norway where the goal is to develop a lipid-rich bacterial meal that can be utilized as fish feed in the aquaculture industry. Carbon-rich waste from an omega-3 production site is used as nutrition for marine bacterial cultures, which are fermented ... -
Default, time-pressured and incentivized deliberate reasoning
(Mastergradsoppgave; Master thesis, 2021-05-14)The purpose of this study was to investigate the effect time-pressure and incentives have on deliberate reasoning. A person’s tendency to engage in and enjoy processes that require reasoning, i.e., their need for cognition, and their algorithmic ability are factors that may moderate performance in reasoning tasks when they are under time-pressure or given monetary reward. Identifying how to increase ... -
Effect of ketosis on pain and quality of life in women with lipedema.
(Mastergradsoppgave; Master thesis, 2022-05-13)Background: Lipedema is an adipose tissue condition in females characterized by immobility, pain, and reduced quality of life (QoL). Recent publications indicate that ketogenic diets may induce symptom relief in women with lipedema. The aim of this study was to investigate the impact of a low-energy ketogenic diet on pain and QoL in women with lipedema, compared to a low-energy non-ketogenic ... -
Process optimization of albumin-stabilized mitotane nanoparticle preparation by dual centrifugation and first lyophilization study
(Mastergradsoppgave; Master thesis, 2022-05-13)Albumin-stabilized mitotane nanoparticles intended for intravenous application can serve as a potential formulation for the treatment of adrenocortical carcinoma. However, the particle size of a nanoparticle-based formulation is crucial for the in vivo behavior of the nanoparticles following an intravenous injection. Prior to this project, the particle size of this nanoformulation had a mean of ... -
Mapping the Well-Being of Norwegian Mothers During the COVID-19 Pandemic
(Mastergradsoppgave; Master thesis, 2022-05-12)The COVID-19 pandemic has had negative effects on people’s well-being and quality of life. In order to extend existing research, we focused on Norwegian mothers with children in elementary schools, and investigated whether the pandemic influenced their well-being, stress, and worries. Our sample consisted of 231 mothers responding in the first data collection that took place June 2020, 97 mothers ... -
Push and pull factors for migration of foreign pharmacists to Norway
(Mastergradsoppgave; Master thesis, 2022-05-12)Migration of foreign pharmacists to Norway has increased considerably in recent years. Data from the Directorate of Health shows that 1592 foreign pharmacists received authorization in Norway from 2013 to 2021 as compared to 1952 Norwegian pharmacists. There are several theories of migration, but “push and pull theory” is the most widely used approach to learn about reasons of migration. According ... -
Computational studies on the human GnRH-I and the GnRH-receptor
(Mastergradsoppgave; Master thesis, 2022-05-12)Gonadotropin-releasing hormone receptor (GnRH-R), which is a Class A G-protein coupled receptor (GPCR), has a vital role in the regulation of sex hormones. The receptor also has a prominent role in diseases, with examples being reproductive cancers and non-reproductive cancers like glioblastoma. Gonadotropin-releasing hormone (GnRH) agonists have been proven to combat cell proliferation in cancers. ... -
An investigation of BK Polyomavirus replication in tubular epithelial cells: New insights into kidney dissemination and neutralising antibodies
(Doctoral thesis; Doktorgradsavhandling, 2024-05-24)BK Polyomavirus (BKPyV) infects most humans and causes an unnoticed lifelong infection of kidney epithelial cells. In immunosuppressed kidney transplant recipients, unchecked high-level BKPyV replication causes BKPyV nephropathy, a disease leading to reduced allograft function and premature allograft loss. The aim of this thesis was to learn more about BKPyV replication and dissemination, as such ... -
The productivity gain by preventing first and subsequent hip fractures in osteoporotic patients as a result of optimal treatment
(Mastergradsoppgave; Master thesis, 2022-05-11)Background: Preventing hip fractures could prevent patient disability and premature death, and lead to substantial societal savings in terms of productivity gains. However, the Norwegian government has decided against emphasizing productivity gains in prioritization decisions for financing pharmaceutical drugs. The question, however, remains whether including productivity gains could lead to better ... -
Medicine articles on English Wikipedia: Quantifying the presence of pharmaceutical industry edits and analyzing their content.
(Mastergradsoppgave; Master thesis, 2022-05-11)Today, Wikipedia has developed into a prominent source for health queries to the vast public. Over the years, some studies have been performed to understand what the webpage can and cannot offer. However, the current literature lacks knowledge of how the pharmaceutical industry is present in Wikipedia’s medicine articles. The immediate objective of this research was to quantify the presence of ... -
Development of DNA Nanoparticles with Properties for Enhanced Biofilm Uptake
(Mastergradsoppgave; Master thesis, 2022-05-11)Microbial biofilms account for up to 80% of all bacterial infections. They are described as small structural communities of bacteria which are embedded in a self-produced extracellular (EPS) matrix. This EPS matrix poses a substantial challenge for antimicrobial treatment by hindering traversal of antimicrobial agents. Nanotechnology based drug delivery systems (DDS) offer a promising solution ... -
Jordmødres erfaringer med å følge fremgang i aktiv fødsel med andre tegn enn vaginal undersøkelse – En kvalitativ studie
(Master thesis; Mastergradsoppgave, 2024-03-11)<p>Hensikt: Å undersøke hvordan jordmødre erfarer å følge fremgang i aktiv fødsel med andre tegn enn vaginale undersøkelser. <p>Problemstilling: Hvordan erfarer jordmødre å følge fremgang i aktiv fødsel med andre tegn enn vaginal undersøkelse? <p>Metode: Kvalitativ forskningsmetode med individuelle dybdeintervju. Malteruds systematiske metode for tekstkondensering ble anvendt for analyse. ... -
Hjemmefødsel – En systematisk litteraturstudie av jordmors erfaringer
(Master thesis; Mastergradsoppgave, 2024-03-08)Bakgrunn: Bakgrunn for studien baserer seg på hjemmefødsel sett fra et jordmorfaglig perspektiv, hvor den faglige vurderingen og erfaringen med hjemmefødsler er av interesse. Hensikt: Hensikten med studien er å sammenfatte litteraturen som omhandler jordmors erfaringer med hjemmefødsler. Problemstilling: Hvilke erfaringer har jordmødre med hjemmefødsel? Metode: Systematisk litteraturstudie ...
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