Recent additions

  • Atg8 family proteins, LIR/AIM motifs and other interaction modes 

    Rogov, Vladimir V.; Nezis, Ioannis P.; Tsapras, P; Zhang, Hong; Dagdas, Yasin; Noda, Nobuo N; Nakatogawa, Hitoshi; Wirth, Martina; Mouilleron, Stephane; McEwan, David G.; Behrends, Christian; Deretic, Vojo P.; Elazar, Zvulun; Tooze, Sharon A.; Dikic, Ivan; Lamark, Trond; Johansen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-19)
    The Atg8 family of ubiquitin-like proteins play pivotal roles in autophagy and other processes involving vesicle fusion and transport where the lysosome/vacuole is the end station. Nuclear roles of Atg8 proteins are also emerging. Here, we review the structural and functional features of Atg8 family proteins and their protein-protein interaction modes in model organisms such as yeast, Arabidopsis, ...
  • LC3B is a cofactor for LMX1B-mediated transcription of autophagy genes in dopaminergic neurons 

    Kournoutis, Athanasios; Johansen, Terje (Journal article; Tidsskriftartikkel, 2023-04-10)
    It is becoming increasingly clear that the Atg8 family of autophagy proteins have roles not only in the cytoplasm, but also in the cell nucleus. In this issue, Jimenez-Moreno et al. (2023. J. Cell Biol. <a href=https://doi.org/10.1083/jcb.201910133>https://doi.org/10.1083/jcb.201910133</a>) report that nuclear LC3B binds to the LIM homeodomain transcription factor LMX1B and acts as a cofactor for ...
  • Jordmødres bruk av fødestillinger i forløsning av barnet og sammenhengen med egen preferanse, kvinners brukermedvirkning og rammefaktorer relatert til klinisk praksis - en tverrsnittstudie 

    Westre, Susanne Bakken; Andersen, Karina (Mastergradsoppgave; Master thesis, 2021-03-18)
    Abstrakt Tittel: Jordmødres bruk av fødestillinger i forløsning av barnet og sammenhengen med egen preferanse, kvinners brukermedvirkning og rammefaktorer relatert til klinisk praksis. Hensikt: Hensikten med studien er gjennom å kartlegge selvrapporterte fødestillinger jordmor har brukt siste året, å undersøke hvilke faktorer som påvirker bruk av fødestilling.   Metode: Tverrsnittstudi ...
  • HIV Infected African Children: Gut microbiota in relation to chronic lung disease and long-term antibiotic treatment 

    Flygel, Trym Thune (Doctoral thesis; Doktorgradsavhandling, 2024-04-19)
    More than half of the population with HIV in the world live in sub-Saharan Africa. HIV-associated chronic lung disease is the most prevalent comorbidity among children and adolescents with HIV in this region. The pathogenesis is multifactorial and thought to be a result of chronic immune activation and repeated lung injury. CD4+ T-cells are the main target for HIV infection. As the majority of CD4+ ...
  • Jordmødres erfaringer i møte med innvandrerkvinner i fødsel som ikke behersker det norske språk. 

    Abdulle, Amran Ahmed; Borrego, Natalia Rebeca Indset (Mastergradsoppgave; Master thesis, 2022-03-15)
    Hensikt: Å utforske norske jordmødres erfaringer i møte med innvandrerkvinner i fødsel som ikke behersker det norske språk. Metode: Kvalitativ metode med åtte individuelle intervju. I dette studiet ble det brukt en hermeneutisk tilnærming og data ble analysert etter livsverden hermeneutikk. Funn: Funnene presenteres gjennom fem temaer: språkbarrierer kan gi disharmoni og hindre deltakelse, ...
  • Cystatin C-Based Equation to Estimate GFR without the Inclusion of Race and Sex 

    Pottel, Hans; Björk, Jonas; Rule, Andrew D.; Ebert, Natalie; Eriksen, Bjørn Odvar; Dubourg, Laurence; Vidal-Petiot, Emmanuelle; Grubb, Anders; Hansson, Magnus; Lamb, Edmund J.; Littmann, Karin; Mariat, Christophe; Melsom, Toralf; Schaeffner, Elke; Sundin, Per-Ola; Åkesson, Anna; Larsson, Anders; Cavalier, Etienne; Bukabau, Justine B.; Sumaili, Ernest K.; Yayo, Eric; Monnet, Dagui; Flamant, Martin; Nyman, Ulf; Delanaye, Pierre (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-26)
    BACKGROUND - The accuracy of estimation of kidney function with the use of routine metabolic tests, such as measurement of the serum creatinine level, has been controversial. The European Kidney Function Consortium (EKFC) developed a creatinine-based equation (EKFC eGFRcr) to estimate the glomerular filtration rate (GFR) with a rescaled serum creatinine level (i.e., the serum creatinine level is ...
  • Transcranial direct current stimulation for chronic headaches, a randomized, controlled trial 

    Hervik, Jill Angela; Vika, Karl Solbue; Stub, Trine (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-27)
    Background and objectives: Chronic headaches are a frequent cause of pain and disability. The purpose of this randomized trial was to examine whether transcranial direct current stimulation (tDCS) applied to the primary motor cortex, reduces pain and increases daily function in individuals suffering from primary chronic headache.<p> <p>Materials and methods: A prospective, randomized, controlled ...
  • Mental Health, Work, Welfare and Vocational Rehabilitation. A Comprehensive Study of Young Adults in the Norwegian Welfare State 

    Wittlund, Sina Marion (Doctoral thesis; Doktorgradsavhandling, 2024-04-11)
    <p><i>Background:</i> Despite Norway's high living standards and robust welfare system, a paradox exists concerning its young working-age adults - low unemployment but high and increasing uptake of health-related welfare benefits, mainly due to mental health problems. My study investigates the relationship between Norway's welfare system, young adults' reliance on health-related benefits, social ...
  • Associations Between Self-Rated Health and Mortality in the Norwegian Women and Cancer (NOWAC) Study 

    Killie, Ida Løken; Braaten, Tonje Bjørndal; Lorem, Geir Fagerjord; Borch, Kristin Benjaminsen (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-20)
    Purpose: We investigated the association between self-rated health (SRH) and cancer incidence and SRH and all-cause mortality among Norwegian women.<p> <p>Population and Methods: We used data from 110,104 women in the Norwegian Women and Cancer (NOWAC) cohort aged 41– 70 years at baseline. We used flexible parametric survival analysis with restricted cubic splines to calculate hazard ratios (HRs) ...
  • "Det handler jo om hvordan en spør" : en kvalitativ metasyntese om fysioterapeuters tverrsektorielle samhandling 

    Frogum, Marit; Vik, Erlend; Forslund, Lina Karin Hellen Gulle; Eliassen, Marianne (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-20)
    Bakgrunn: Helsetjenestens organisering med en inndeling i spesialist- og kommunehelsetjeneste krever i stor grad samhandling på tvers av sektorene. Fysioterapeuters praktiske tilnærming til faget kan skape utfordringer for samhandling på tvers av organisatoriske grenser med ulike kontekstuelle og kulturelle rammer. Hensikten med denne studien er å undersøke fysioterapeuters intraprofesjonelle ...
  • A Systems Epidemiology Approach to Breast Cancer and Parity. The Norwegian Women and Cancer (NOWAC) Study 

    Krum-Hansen, Sanda (Doctoral thesis; Doktorgradsavhandling, 2024-04-04)
    The incidence and prevalence of breast cancer (BC) are increasing worldwide. The reasons for this trend are partly unknown. BC has several well documented modifiable and non-modifiable risk factors. The only known, natural protective factors are breastfeeding and parity. The current paradigm is that the protective effect of parity is mediated by permanent genomic changes in a woman’s breast tissue ...
  • Most common health problems in general practice among adolescents, and young adults’ survivors of lymphoma: a register-based cohort study in Norway 

    Upreti, Ramesh; Mmbaga, Elia; Haugnes, Hege Sagstuen; Kiserud, Cecilie E.; Kollerud, Ruby del Risco (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-28)
    Background - The aim was to investigate the distribution of health problems in general practice (GP) among adolescent and young adult (AYA) survivors of lymphoma and to compare problem rates with the general population.<p> <p>Methods - All GP consultations between 2006 and 2020 were identified from the national GP claims register. Diseases and complaints presented 3–10 years after the cancer ...
  • Characteristics of urban neighbourhood environments and cognitive age in mid-age and older adults 

    Soloveva, Maria V.; Poudel, Govinda; Barnett, Anthony; Shaw, Jonathan E.; Martino, Erika; Knibbs, Luke D.; Anstey, Kaarin J.; Cerin, Ester (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-12)
    In this cross-sectional study, we examined the extent to which features of the neighbourhood natural, built, and socio-economic environments were related to cognitive age in adults (N = 3418, Mage = 61 years) in Australia. Machine learning estimated an individual's cognitive age from assessments of processing speed, verbal memory, premorbid intelligence. A ’cognitive age gap’ was calculated by ...
  • Dietary intake of total, heme and non-heme iron and the risk of colorectal cancer in a European prospective cohort study 

    Aglago, Elom K.; Cross, Amanda J.; Riboli, Elio; Fedirko, Veronika; Hughes, David J.; Fournier, Agnes; Jakszyn, Paula; Freisling, Heinz; Gunter, Marc J.; Dahm, Christina C.; Overvad, Kim; Tjønneland, Anne; Kyrø, Cecilie; Boutron-Ruault, Marie-Christine; Rothwell, Joseph A.; Severi, Gianluca; Katzke, Verena; Srour, Bernard; Schulze, Matthias B.; Wittenbecher, Clemens; Palli, Domenico; Sieri, Sabina; Pasanisi, Fabrizio; Tumino, Rosario; Ricceri, Fulvio; Bueno-de-Mesquita, Bas; Derksen, Jeroen W. G.; Skeie, Guri; Jensen, Torill; Lukic, Marko; Sánchez, Maria-Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Barricarte, Aurelio; Ericson, Ulrika; van Guelpen, Bethany; Papier, Keren; Knuppel, Anika; Casagrande, Corinne; Huybrechts, Inge; Heath, Alicia K.; Tsilidis, Konstantinos K.; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-09)
    Background - Iron is an essential micronutrient with differing intake patterns and metabolism between men and women. Epidemiologic evidence on the association of dietary iron and its heme and non-heme components with colorectal cancer (CRC) development is inconclusive.<p> <p>Methods - We examined baseline dietary questionnaire-assessed intakes of total, heme, and non-heme iron and CRC risk in the ...
  • Novel biomarkers in hypertension 

    Brobak, Karl Marius (Doctoral thesis; Doktorgradsavhandling, 2024-04-11)
    <p><i>Introduction</i> Hypertension and kidney damage are reciprocally related. Current blood and urine tests cannot reliably detect early kidney damage from hypertension, hindering timely prevention. A biomarker that captures kidney damage due to hypertension at an early stage might improve risk stratification and treatment. The primary objective of this project was to investigate how biomarkers ...
  • Er en-avlednings elektrokardiografi assosiert med hjerteinfarkt hos yngre og middelaldrende kvinner og menn? En prospektiv kohortstudie, Tromsøundersøkelsen 1986/87. 

    Aalstad, Brita (Master thesis; Mastergradsoppgave, 2021-03-02)
    Sammendrag Introduksjon Bakgrunnen for oppgaven er at det finnes lite forskning på assosiasjon av hjerteinfarkt ved elektrokardiografi hos kvinner. Formålet er derfor å studere sammenhengen mellom EKG avledning I og hjerteinfarkt hos hjertefriske yngre og middelaldrende kvinner og menn. Material og metode Datamaterialet til denne prospektive kohortstudien er hentet fra den tredje Tromsøundersøkelsen ...
  • Eventyret i kommersiell hundekjøring: En kvalitativ studie av hundekjøringsguidens kompetansekrav og -utvikling 

    Wied, Anja Åse (Master thesis; Mastergradsoppgave, 2023-12-15)
    Dette prosjekt undersøker hvilke kompetansekrav som settes til hundekjøringsguiden og hvordan denne kompetanse kan utvikles. Hundekjøringsguidens rolle er et uberørt forskningsfelt og prosjektet er første forskning på temaet. En forståelse for hundekjøringsguidens rolle kan bidra til en inkludering av hundekjøring i en profesjonaliseringsprosess av naturbasert reiseliv. Prosjektet undersøker guidens ...
  • Utøvelse og utvikling av radiografifaget i Norge. En kvalitativ studie 

    Egestad, Helen; Hofvind, Solveig Sand-Hanssen; Fjellaksel, Richard (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-18)
    Innledning - Økt arbeidstempo og mer krevende arbeidsoppgaver gjør at radiografer har behov for å videreutvikle kunnskaper og ferdigheter. Hensikten med studien var å undersøke hvordan norske radiografer opplever arbeidshverdagen og hvilke muligheter de har for å opprettholde og øke egen fagutvikling. <p> <p>Materiale og metode - Vi gjennomførte semistrukturerte intervjuer av ti radiografer fra ...
  • A Global Meta-Analysis of Depression, Anxiety, and Stress Before and During COVID-19 

    Daniali, Hojjat; Martinussen, Monica; Flaten, Magne Arve (Journal article; Tidsskriftartikkel; Peer reviewed, 2023)
    Objective: This meta-analysis compared negative emotions (NEs) as depression, anxiety, and stress, from before the pandemic to during the pandemic. <p> <p>Method: A total of 59 studies (19 before, 37 during-pandemic, and 3 that included both) using the Depression, Anxiety and Stress Scale (DASS) were included. A random effects model estimated the means of NEs before and during the pandemic. ...
  • Prophylactic Oropharyngeal Surfactant for Preterm Newborns at Birth: A Randomized Clinical Trial 

    Murphy, Madeleine C.; Miletin, Jan; Klingenberg, Claus Andreas; Guthe, Hans Jørgen Timm; Rigo, Vincent; Plavka, Richard; Bohlin, Kajsa; Barroso Pereira, Almerinda; Juren, Tomáš; Alih, Ekele; Galligan, Marie; O'Donnell, Colm P. F. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-11)
    Importance - Preterm newborns at risk of respiratory distress syndrome are supported with continuous positive airway pressure (CPAP). Many newborns worsen despite CPAP and are intubated for surfactant administration, an effective therapy for treatment of respiratory distress syndrome. Endotracheal intubation is associated with adverse effects. Pharyngeal administration of surfactant to preterm animals ...

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